J. Matt

[J. Matt @johnmatt]

Yee A, et. al. Phage display broadly identifies inhibitor-reactive regions in von Willebrand factor. J Thromb Haemost. 2021 Nov;19(11):2702-2709. doi: 10.1111/jth.15460. Epub 2021 Jul 28. PMID: 34255925; PMCID: PMC8530901.
#ASH2023

[J. Matt @johnmatt]

https://t.co/a4R17zTWTw

[J. Matt @johnmatt]

July 4, 2019
N Engl J Med 2019; 381:89-91
DOI: 10.1056/NEJMcibr1903249
#ASH2023

[J. Matt @johnmatt]

tPA is expressed all over the mouse brain. Fascinating plenary talk by Dr. Robert Medcalf at #ISTH2022

[J. Matt @johnmatt]

Plasminogen predates tPA by 70 million years! Fascinating plenary by Dr. Robert Medcalf at #ISTH2022

[J. Matt @johnmatt]

Important to remember that some TTP patients will NOT have schistocytes on their initial blood smear. Data from the UK TTP registry presented by Andrew Doyle at #ISTH2022

[J. Matt @johnmatt]

Very cool talk by Tim Postmus from KU Leuven about introducing N-glycans on the surface of the spacer domain of ADAMTS13 to avoid pathogenic autoantibodies the vast majority of iTTP! #ISTH2022

[J. Matt @johnmatt]

The Austrian experience with PLEX-free treatment of TTP in 20 patients with Caplacizumab+Rituxan+steroids presented by Paul Knöbl. #ISTH2022
-median 3 days to platelet count normalization
-2/20 patients required plasma exchange
-1 subdural hematoma on day 21 of Caplacizumab

[Blood Journals Portfolio @BloodPortfolio]

How I manage autoimmune cytopenias in patients with lymphoid cancer https://t.co/DCvhldlUWD

[Ahmed Ghoneem, MD MSc @a_h_ghoneem]

LV thrombi (LVT)

👉Are associated with systolic dysfunction.
👉Can occur in both ischemic & non-ischemic cardiomyopathy.
👉Carry a significant risk of systemic thromboembolism.

Management is mainly anticoagulation, but would you choose WARFARIN or a DOAC?? A #tweetorial 🧵

[Michael Makris @ProfMakris]

Having lived through Hurricane Katrina as a #Hemophilia doctor, Cindy Leissinger explained the essentials advice she would give to prepare for another such eventuality. #EAHAD2022

[Al-Ola A Abdallah MD (USMIRC) @Abdallah81MD]

Daratumumab interferes with blood bank testing by binding to CD38 on RBCs causing panagglutination on the Indirect Antiglobulin Test (IAT). The time to resolution of positive IAT after discontinuation in some studies is 5 months #mmsm #MYELOMA #MedEd #medtwitter #USMRC

[HTRSFellows @HTRSFellows]

Fascinating tweetorial on how alcohol (even independent of liver disease) causes macrocytosis!

#hemetwitter

[Michael Makris @ProfMakris]

Letter in tomorrow's @NEJM shows that it is safe for individuals who have had VITT to receive a second #COVID19 vaccine. The data are largely with the use of the Pfizer vaccine, although interestingly some patients received a second AZ vaccine. https://t.co/uPKSRCTnSr

[Michael Makris @ProfMakris]

If you are looking for a review article for an update on the management of Immune Thrombocytopenia (ITP), this is excellent and very practical. The PDF is free. https://t.co/XgsjEvGkuN

[flora peyvandi @flora_peyvandi]

How I treat dysfibrinogenemia | Blood | American Society of Hematology https://t.co/PV8M8Cz3rk

[Laura Haynes @LMHaynesPhD]

Y'all, our latest paper is out and as a first for me I don't think I mention "thrombin" once!

https://t.co/gwSSqJ9z0i

[Pat McGann, MD @PTMcGann]

#SickleCellAwarenessMonth

Labs NEVER override symptoms

Yes, we will get a CBC

Most times it will be “at baseline”

This 1000% does NOT mean that sickling is not occurring

Don’t EVER use labs to explain away any symptom, especially pain

Believe the patient and treat symptoms

[Ariela Marshall MD @AMarshallMD]

Interested in #hematology and #pregnancy? Great electronic conference coming soon, CME credit offered!
https://t.co/ywp5xA7rII

#MedTwitter #MedEd @ASH_hematology @isth @MaryCushmanMD @PennMedicine @MiddeldorpS @connors_md @DrMMurphy

[Karima Khamisa @DrKhamisa]

Think of this when you see lots of schistocytes but normal platelet count