Jon Beagan

Exploring the epigenome as a computational biologist at Precede Bio. Former LSRF Postdoc Fellow of the Colon-Ramos lab (Yale), PhD from the Cremins lab (UPenn).

[Dana-Farber’s Breast Oncology Center @DFCI_BreastOnc]

Congratulations to Stefania Morganti, MD (@StefiMorganti) and Tess A. O'Meara, MD, MHS (@tess_omeara) on their @ConquerCancerFd Young Investigator Awards! #ASCO26

[Sylvan Baca MD PhD (Hiring!) @SylvanBacaLab]

Fascinating study at the intersection of #liquidbiopsy and #genetics led by Ziwei Zhang and Surya Chhetri: https://t.co/ArOo6JS8HG. They found that circulating chromatin in blood can reveal how genetic variants contribute to disease by affecting gene regulation.

[Paolo Tarantino @PTarantinoMD]

So much food for thought in @tompowles1’s lecture on ADC combos

A few key points:
- synergy is rare, but additive is often transformative
- activity of combos is tumor-specific
- the ADC target matters. The payload matters. The linker matters
- innovation in biomarkers is needed

[Colón-Ramos Lab @Colon_Ramos_lab]

📢We are looking for a Postdoctoral Associate in Neuronal Metabolism to join our team! See flyer for info:

[Jon Beagan @jonbeagan]

So cool!

[Rongxin Fang, Ph.D. @RongxinFang]

Activity-dependent enhancer RNA produces hybrid DNA:RNA R-loop structures that support three-dimensional chromatin looping between enhancer and promoter and rapid Npas4 gene induction in the brain.
https://t.co/pkWCIGSc07

[Erin Dunn, ScD, MPH @ErinDunnScD]

Do you have a passion for (epi)genetics & mental health? The Dunn Lab at @PurdueLibArts is hiring a Research Asst./Assoc. Professor to lead research projects, mentor lab members & disseminate findings. #sciencejobs #EpiJobs

Please RT & reach out for info:
https://t.co/jiU52VQKN8

[William J. Greenleaf @WJGreenleaf]

The Greenleaf and Pasca Labs are looking for graduate students and postdocs interested in perturbing transcription factors and chromatin remodelers in human brain organoid systems with an aim of quantitatively understanding drivers of normal human development. Email Will!

[Daniel Colón Ramos @dacolon]

Going to #CeNeuro2024 ? Check out this poster from the lab!
Other posters/presentations from lab:
21: Talk by Sarah Emerson on allometry of nerve ring
P137: Poster by Malcom on electrical synapses and behavior

[Dana-Farber’s Breast Oncology Center @DFCI_BreastOnc]

#ASCO24 Poster Session👉Novel epigenomic liquid biopsy assay to predict estrogen receptor status and to infer ER pathway activation in #BreastCancer. (Abstract: 1066) @StefiMorganti @hthrparsons @nlinmd @stolaney1 @jonbeagan @AparnaGorthi @corrie_painter
👉https://t.co/XQvFzXvrF6

[Evgeny Kvon @evgenykvon]

How do enhancers work over distances that sometimes exceed megabases? Excited to share our work led by @gracecbower where we uncover a unique sequence signature globally associated with long-range enhancer-promoter interactions in developing limb buds: https://t.co/n0p7BdxSdq 1/

[Daniel Colón Ramos @dacolon]

Pura es una postbac en mi laboratorio rumbo a escuela graduada en Harvard. Ella comparte su experiencia de postbac abajo. Estamos contratando para posiciones de postbac nuevamente. Si estas interesad@ en una experiencia similar, ¡solicita al laboratorio! Información abajo

[Jon Beagan @jonbeagan]

@Bahmanyarlab @FrancesEMoore2 @NSF Congrats @FrancesEMoore2 !!

[Jason Buenrostro @JD_Buenrostro]

We are recruiting postdoctoral fellows in neurobiology and development to complement our group specializing in genomic technologies, epigenetics and machine learning. projects are very well funded and we are interested in co-mentorship. Please DM if interested in hearing more!

[linda.zhou @lindazh0u]

We are very excited to share our findings on BREACHes using a human model of genome instability in fragile X syndrome with possible implications for other diseases with perturbations linked to genome instability! https://t.co/t68X7KxSUP. (1/18)

[Jesse Engreitz @jengreitz]

An encyclopedia of enhancer-gene regulatory interactions in the human genome

https://t.co/lxzN7cQTGA

Very proud—4 years in the making, huge team effort.

This is a paper where the author list cannot convey everyone's incredible contributions.

My holiday highlights below:

1/

[Dana-Farber’s Breast Oncology Center @DFCI_BreastOnc]

#SABCS23 | Poster Spotlight Session |#LiquidBiopsy determination of #HER2 status in #BreastCancer: Results from a novel epigenomic platform.
@hthrparsons @nlinmd @SylvanBacaLab @PTarantinoMD @stolaney1 @DrChoueiri
https://t.co/QRoP0xJE3z

[Daniel Colón Ramos @dacolon]

We are at #SfN2023 in DC! Want to learn about the lab? Please attend @patychanaba talk on Monday, Nov 13, 2:45pm in WCC140. Want to learn @WuTsaiYale opportunities (faculty, postdoc or grad school)? Or want to just say hi? Join me at booth 3216 this afternoon after 2:30 pm

[John Murray @jisaacmurray]

I'm happy to share a review Kelly Liu and I wrote for #WormBook in #Genetics: "Mechanisms of lineage specification in Caenorhabditis elegans." https://t.co/2Q5qPSVgRg

[Nature Medicine @NatureMedicine]

Out today for #ESMO23: In a large multi-cancer cohort, a single liquid biopsy assay enables the detection of four epigenomic modifications, allowing the monitoring of expression of potential drug targets and resistance genes @SylvanBacaLab @DrChoueiri https://t.co/NGjEj7KxdF

[Jon Beagan @jonbeagan]

Thrilled to be joining this awesome team!

[Precede Biosciences @Precede_Bio]

NEWS: Introducing our first-in-class liquid biopsy platform, revolutionizing #healthcare by unlocking new insights from just 1mL of plasma.

We are excited to make this announcement as we emerge from stealth mode! Learn more https://t.co/22UpFNF6q9 #oncology (1/2)