This has quietly been a miracle month in medicine.
In the last 5 weeks we’ve got news on:
- retatrutide, the triple agonist GLP-1 from Lilly, basically melting fat and body-wide inflammation at record levels
- RevMed’s new pancreatic cancer drug showing unprecedented abilities to extend life
- small trial of a one-and-done PCSK9 gene editing therapy for slashing LDL cholesterol
- Mayo’s AI-assisted radiology showing vastly improved cancer detection
- this new therapy for metastatic solid tumors
This stuff is at varying levels of evidence. Retatrutide is ~100% on its way, other stuff needs more clinical trial data. But put it together and we’re maybe on the verge of majorly reducing the mortality of heart disease and cancer, the two leading causes of death in America.
Just published @NatureMedicine and presented @ASCO
Advanced, refractory solid cancers treated with a bispecific T cell engager (BiTE, Figure), Phase 1 trial, with or without Keytruda, in 61 patients. Some very favorable responses with "manageable safety profile"
https://t.co/MkzQXY1psA
US nonprofit hospitals spent $7.8 billion on management consultants from 2009 to 2023, but contracts were not associated with meaningful changes in finance, operations, or quality of care. 🧵
https://t.co/QQswMYxrG8
The Philadelphia Eagles drafted a 21 year old Nigerian who has never played football but stands 6’5”, 306 lbs with 6% body fat, a 39” vertical, a 10’10” broad jump that is 14 inches longer than any other defensive tackle at the HBCU combine, and a 4.63 40 yard dash
@TheCavsJack ✍️🔥🔥 First pic is a man ready to destroy everything in his path 😤 second pic is a man wondering why he’s still doing this at 41 😭 that is NOT the same look 💀
“Africa is a paradox which illustrates and highlights neo- colonialism. Her earth is rich, yet the products that come from above and below the soil continue to enrich, not Africans predominantly, but groups and individuals who operate to Africa's impoverishment.”
~ Kwame Nkrumah
BREAKING: Étienne Davignon, 93 year old coloniser and former EU supremo, has been charged with complicity in the murder of Patrice Lumumba. This is genuinely huge news. Great news.
"Every day for the thief, one day for the owner" - African proverb.
As a politician you can have your foot on the neck of Nigerians and they will look up with genuine admiration and say, wow boss, nice shoes. Nigerian politicians are the luckiest in the world.
Francis Ngannou fired back at critics claiming he ruined his legacy after the UFC:
“You can’t go to the store and pay with legacy. This is bullsh*t promotions feed fighters, that they’re fighting for legacy. Good for you. Keep the legacy, give me my pay.” 😳
(via @fighthype)