JasminSTowers

Scientist @altos_labs Cambridge Institute | @ReikLab Babraham Institute | JRF @DarwinCollege | PhD PenningerLab @imba_vienna

[JasminSTowers @JTaubenschmid]

Happy to see this out in @CellStemCell! 8C-like cells capture the human zygotic genome activation program in vitro. Details here 👉
https://t.co/tQSaMHMyiy

[Hallou Lab @Hallou_Lab]

Please get in touch📧if you would like to apply for a prestigious Newton Fellowship @royalsociety in my lab @KirOxford @UniofOxford! Exciting wet lab🔬🧬& computational💻projects on tissue spatial transcriptomics and mechanobiology are available!

[Jannat Ijaz @sciencejannat]

Very excited to share that our work reconstructing chromothripsis has now been published in @CellGenomics! We reconstructed chromosomes with up to 800 rearrangements on a single allele and queried epigenetic and transcriptomic consequences. Thread below!

https://t.co/LWzYFYPPPV

[Reik Lab @ReikLab]

Preprint alert 🎉🐁👩‍🔬🧬! @OanaKubinyecz used Trim Away to deplete SMARCA5 in mouse zygotes and found that in its absence major ZGA is impaired in 2-cell embryos. https://t.co/0FamCGasYf

[Rugg-Gunn Lab @RuggGunnLab]

Happy to share our latest review on "Epigenetic regulation of early human embryo development". Huge thanks to authors Amy Wilkinson @AmyWilkinson25 and Irene Zorzan @irene_zorzan, and to our colleagues and reviewers for contributing ideas and discussion.

https://t.co/My41YwSAoD

[Edward Grow, PhD @ControllingLMNT]

Amazing story on mouse Obox cluster of genes & their function in zygotic genome activation. A major missing puzzle piece!

Tandem arrays (mouse Obox cluster, Dux/DUX4, Zscan4, 🦓🐠 mir430) seem to be a ZGA commonality. https://t.co/1gp2r7lsyj
Paula Stein @xielablife @CarmenRepro

[ZZ Zhao Zhang @zz_zhaozhang]

Our new work in ⁦@Nature⁩ to explain how retrotransposons synthesize the 2nd-strand DNA by a circularization process.

Story: made some cool findings (we thought) -> actually scooped 40-yr ago by textbook knowledge -> textbook appear to be incorrect. https://t.co/7Glvf2qFEw

[Jacob Corn @jcornlab]

Cells degrade unfolded proteins. But do they also check for chemical damage? We found that a C-terminal amide is completely sufficient for degradation by an SCF/FBXO31 ligase complex! With @bode_lab @matthias_muhar @jakobfarnung. https://t.co/Wtidapo1VT 🧵

[Ariane Lismer @arianelismer]

What began as a few concept being kicked around in stimulating & memorable discussions, progressed into a comprehensive piece on paternal epigenetic inheritance. I am very excited to share @KimminsSarah and I’s Perspective out today in @NatureComms! https://t.co/0LWwAZtIIC

[JasminSTowers @JTaubenschmid]

A long time in the making – but I am very happy to see our collaborative effort with @penningerlab @IMBA_Vienna finally published in @EMBOMolMed “A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors” https://t.co/T98mFoGHra

[EMBO Mol. Medicine @EmboMolMed]

Happy Monday! 🙂
Online today: A whole-genome scan for #Artemisinin cytotoxicity reveals a novel therapy for human #BrainTumors

By J. Taubenschmid-Stowers, JM Penninger & colleagues
@IMBA_Vienna @UBC

🗞️Read #openaccess: https://t.co/775eq9C7fq

[Miguel Branco @BrancoLab]

PhD opportunity in our lab, jointly with @altos_labs. Sep 2023 start. Spread the word to all your awesome students.

[Martin Denzel @MartinD79]

Hi 👋 science twitter!

Are you into genetic screens and small molecule drug discovery? We are looking for a pharmacogenomics enthusiast!

The position will be located at @altos_labs in Cambridge UK and is part of our Institute of Medicine

Pls RT!

https://t.co/pNFCTbpvhr

[Astrid Hagelkruys @AHagelkruys]

Very happy to see our paper about the in vivo functions of the two HUSH-proteins MPP8 and MORC2 published in @ScienceAdvances: https://t.co/fctK0GbUPK
A big thank you to everyone involved and especially to my brilliant master's student @HorrerMarion!

[IMBA imbavienna.bsky.social @IMBA_Vienna]

The Austrian Academy of Sciences is hiring a Scientific Director for IMBA. Please RT.

➡️ Deadline for Applications: October 31, 2022
➡️ APPLY: https://t.co/fzOs2yu2DY

@viennabiocenter @oeaw
#director #jobs #research #hiring

[JasminSTowers @JTaubenschmid]

Join us at the Cambridge Epigenetics Club Summer Symposium 2022 on 26th July at @BabrahamUK with our fantastic keynote speakers @AnaBoskovic18 and @AnneF_S. Free registration and abstract submission here 👉 https://t.co/kYTquB8cpP ! https://t.co/4lrGMqAY2g

[CambridgeEpigenetics @EpigeneticsClub]

Cambridge Epigenetics Club Summer Symposium will be held in person July 26th @BabrahamUK - apply now to present a talk or poster in person here: https://t.co/YajfcTGcmo
Keynotes from Ana Boskovic @AnaBoskovic18 & Anne Ferguson-Smith @AnneF_S Hope to see you there!

[Reik Lab @ReikLab]

Big congratulations to @OanaKubinyecz for being awarded the #EMBOWorkshop #MZT2022 Poster Prize for her exciting new findings regarding the ‘Awakening of the Genome’. Fantastic meeting! Thanks to the amazing organisers!

[Cell Stem Cell @CellStemCell]

New Article online now CellStemCell: Amniogenesis occurs in two independent waves in primates https://t.co/CLvaRNq7vB

[Moritz Bauer @MoritzBauer_87]

Since we can now host more people at the #DutchArtificialEmbryoMeeting, we have plenty of spots available for you guys! The deadline is soon so REGISTER NOW to meet your peers and show your work!

[Cell Stem Cell @CellStemCell]

Preview in this issue of CellStemCell: Human 8-cell-like cells discovered https://t.co/c8nmx9BFpp

[JasminSTowers @JTaubenschmid]

Thank you Babraham Institute for supporting this work!

[Babraham Institute @BabrahamInst]

.@JTaubenschmid and colleagues have discovered a new type of stem cell that resembles cells in the early human embryo during the transition of ‘genomic power’ from mother to embryo

Full story ➡️ https://t.co/ZPKaX8GcPD
#epigenetics #DevelopmentalBiology @ReikLab

[JasminSTowers @JTaubenschmid]

https://t.co/yu7SN2FD10

[JasminSTowers @JTaubenschmid]

Super excited to share our latest preprint 🥳🎉🍾,
“Modelling human zygotic genome activation in 8C-like cells in vitro”! 👇

https://t.co/CjMtmOyMFy

[JasminSTowers @JTaubenschmid]

Happy to see this out in @CellStemCell! 8C-like cells capture the human zygotic genome activation program in vitro. Details here 👉
https://t.co/tQSaMHMyiy

[JasminSTowers @JTaubenschmid]

We have discovered human 8-cell-like cells that express genes, endogenous retroviruses and proteins similar to 8-cell embryos, and can be used to study the molecular principles of human embryonic genome activation in stem cells in vitro. See the 🧵 below 👇