Tranexamic acid (TXA) useful only in anticoagulated patients: OR 0.17 for bleeding complications. P0731 study, 932 patients, 30 centres. Game changer for high-risk enucleation. Should probably be standard protocol. "Efficacy of tranexamic acid in reducing intraoperative bleeding during TURP: systematic review and meta-analysis of RCTs." 2026.→ PMID: 41695713 → https://t.co/H4qpfhbRUl but "Efficacy of tranexamic acid in reducing intraoperative bleeding during TURP: systematic review and meta-analysis of RCTs." 2026.
→ PMID: 41695713 → https://t.co/H4qpfhbRUl
Radical prostatectomy vs radiotherapy in high-risk #ProstateCancer: Emulated randomized comparison with individual patient data from two phase III randomized trials.
- A new emulated RCT analysis finds that radiotherapy + long-term ADT results in lower distant metastasis rates vs. radical prostatectomy in high-risk #ProstateCancer.
- ~80% of surgery patients required additional treatment. More data needed on intensified multimodal approaches.
Presented by @Soum_Roy_RadOnc@RushCancer. #GU25 written coverage by @zklaassen_md@GACancerCenter > https://t.co/PaL8Rfvd5G @ASCO
External validation of nomograms for predicting lymph node invasion (LNI) in prostate cancer patients with negative PSMA PET-CT. What did we find? The Briganti 2023 nomogram is the most accurate! 📊✅
🔍 Why does it matter?
Extended pelvic lymph node dissection (ePLND) is the gold standard for staging but comes with risks. With PSMA PET-CT revolutionizing imaging, we need better predictive tools to avoid unnecessary procedures.
📌 Key Findings:
•Among 282 patients, 13% had LNI despite negative PSMA PET-CT.
•The Briganti 2023 nomogram outperformed others (C-index: 77% vs. MSKCC 64%, Briganti 2017 69%, Amsterdam-Brisbane-Sydney 64%).
•Using a 5% risk cutoff would spare 47% of ePLND procedures while missing only 3.8% of LNI cases! 🚫🔬
⚖️ Clinical Impact:
•Improves decision-making: More precise risk stratification means fewer unnecessary surgeries.
•Saves patients from complications: ePLND has side effects; avoiding it when possible is crucial.
•Guides personalized treatment: Selecting the right patients for ePLND enhances care quality.
👨⚕️ Takeaway: The Briganti 2023 nomogram should be the go-to tool for predicting LNI in prostate cancer patients with negative PSMA PET-CT! 📈
🔗 Read the full study here: https://t.co/VrfJ25sjFX
#ProstateCancer #Urology #PSMAPET #LymphNodeDissection #Nomogram
Subestudio POISE 3: El uso del ácido tranexámico en #Cirugía general, un bolo al inicio y otro al final, disminuye significativamente el riesgo de #sangrado perioperatorio, sin aumentar la incidencia de eventos tromboembólicos. @JAMA_current 2025 #Cirujanos
Cancer Statistics 2025 are out! #prostatecancer incidence still on the rise, mortality basically flat. Get screened so you can get treatment _when needed_. #pcsm
https://t.co/CS7SKz6Tuc
Spotlight: EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer—2024 Update. Part I: Screening, Diagnosis, and Local Treatment with Curative Intent by @philcornford et al
Full article here: https://t.co/fhb75q5xQL
#eauguidelines#ProstateCancer#PCa #eauguidelines2024update #Spotlightarticle #eururol #urosome #MedTwitter
Many urologists struggle to understand laser physics relevant to enucleation. Watch this fantastic talk https://t.co/ngg44Kq2rX by Associate Professor @eug20miglia on endourological lasers in tissue applications. He simplifies laser physics and goes straight to the point. It's a must-see talk for every urologist who uses lasers for the treatment of urological conditions.
Nice summary of where we are with the DRE. Academic urologists--do you still ask your team to include with their H&P?
Is Era of the Digital Rectal Examination (DRE) for Prostate ... : JU Open Plus https://t.co/NOstAfUuXh
Comparing the Performance of Digital Rectal Examination and Prostate-specific Antigen as a Screening Test for Prostate Cancer: A Systematic Review and Meta-analysis by Akihiro Matsukawa et al
https://t.co/xcIgyxDRtZ
#UroSoMe#MedTwitter#EUO#PCa#ProstateCancer
Many patients with prostate cancer detected by systematic biopsy have clinically insignificant disease. A screening strategy based on prostate-specific antigen & MRI could decrease detection of insignificant cancer. Learn more in a new Quick Take video: https://t.co/MOUhxpSvLC
Spotlight: A Detailed Evaluation of the Effect of Prostate-specific Antigen–based Screening on Morbidity and Mortality of Prostate Cancer: 21-year Follow-up Results of the Rotterdam Section of the European Randomised Study of Screening for Prostate Cancer by @IvodeVos , Annick Meertens et al
Watch all our Spotlights here: https://t.co/T4jVPWYuUT
#Spotlight #UroSoMe #MedTwitter
PCa–specific and All-cause Mortality After Robot-assisted Radical Prostatectomy: 20 Years’ Report from the European Association of Urology Robotic Urology Section Scientific Working Group by @UFalagario, @sophieknipper et al
https://t.co/H25cqq757a
#UroSoMe#MedTwitter#EUO
🇪🇸 | HISTÓRICO
Médico español extirpa un tumor renal a un paciente en China desde 8.000 km de distancia usando un robot. ¡Primera cirugía transcontinental del mundo de este tipo!
Evolution of robotic urology in Germany:
🖥️ 150,432 robot-assisted vs 733,416 open surgeries
📉less ICU admissions, transfusions, and length of hospital stay
📊increasing uptake across all procedures
@LMU_Muenchen@pyrgidis@gb_schulz
https://t.co/imXpvHp3l2