This is classic #pinduoduo playbook in #Singapore and #Malaysia: test first, adjust on the fly, and if the returns are good, pour in resources without hesitation👉 https://t.co/k8C9dZfRmo
"The child wishes to care, but the parents are gone." This Chinese saying came to mind after reading a NTU prof's comments on #DearYou. It led me to reflect on my grandma's journey from Kinmen to wartime Singapore and why stories like hers still matter👇https://t.co/uS0jI4HsHR
For my first post, I’m sharing a letter @NVIDIA signed on why open models matter.
AI will transform every industry, power every company, and be built by every country.
Open models strengthen safety and cybersecurity, accelerate innovation and diffusion, and enable sovereignty.
The world needs both frontier closed models and frontier open models.
https://t.co/AUKzoQ5Ikb
A former engineer + Oxford MD + Imperial ML PhD just sequenced and analyzed his own genome… from his living room. 🧬🏠
Seth Howes was driven by something deeply personal: generations of autoimmune disease in his family, including a sister who nearly died waiting for a liver transplant.
Instead of relying solely on hospitals, he built a DIY genomics lab at home:
🔹 A pocket-sized MinION sequencer
🔹 AI genome models (Evo2 + AlphaGenome)
🔹 Claude as a natural-language bioinformatics copilot
The shocking part isn’t just that he sequenced DNA at home.
It’s that AI removed the expertise barrier.
What once required:
💰 $2.7B infrastructure
🏢 Elite institutions
👨🔬 Specialized teams
…can now be approached by one highly capable individual with consumer-grade tools and AI assistance.
This feels like biology’s “personal computer moment.” 💻➡️🧬
Computing escaped the lab.
Publishing escaped the newsroom.
Now biology may be escaping institutions.
The next biotech breakthrough might not start at Big Pharma — but in someone’s living room. 🚀
#AI #Biotech #Genomics #Bioinformatics #SyntheticBiology #PersonalizedMedicine #DigitalBiology #ClaudeAI #DeepMind #Innovation #FutureTech
I’ve wanted to do this for a decade.
But I never did - I refuse to give any company my DNA.
It is me.
So this week I sequenced my genome entirely at home. Literally on my kitchen table.
I never exposed my DNA sequence to the internet. Not at any point.
I used a MinION to do the sequencing (it’s smaller + weighs less than an iPhone).
I used open-source DNA models for the analysis (Evo2 and AlphaGenome) running locally on a DGX Spark and Mac Studio.
I traced mechanisms behind my family’s multigenerational autoimmune conditions that no clinician has been able to understand.
When I set out to do this I didn’t know if it would actually work. It does.
Your genome is the most private data you will ever have. You probably shouldn’t let it leave your house.
The ZIRP-era PM playbook is starting to feel dated 🏛️
• 📚PRDs
• 🎭Roadmap theater
• 🔁Alignment loops
Made sense when execution was slow and capital was cheap, now it mostly gets in the way.
AI-native PM is the shift ⚡
The job isn’t process; it’s:
• Knowing what to build
• Getting it into users’ hands fast
The moat has moved to:
• 🎯 Taste
• 🧠 Judgment
• ⚡ Speed
Winners won’t “plan better.” They’ll ship something magical by Friday.
#ProductManagement #AI #ProductStrategy #TechLeadership #Innovation #ProductThinking #AIProducts
https://t.co/h35KYrs1eO
10/ 🔋THE BATTERY SWAP PARADOX: 10-Minute Penalties Nobody's Talking About
Honor Lightning: 3 swaps | 10.6km per charge | 50:26
Industry avg: 4-5 swaps | 5-7km per charge | 1:28:00
Honor's edge: -40% fewer swaps than average. But still 3 human interventions for 21km.
If Honor could eliminate all 3 battery swaps, their time would drop from 50:26 to ~20:26. That's 36 minutes faster than any human alive.
So the real race isn't robot vs human. It's battery tech vs physics.
Who's betting on the battery breakthrough? 👇
#PhysicalAI #HumanoidRobots #AIHardware #TechChina #TechStrategy
https://t.co/hVXyitrupd
The 10 Most Insane Stats from the 2026 Beijing Yizhuang Humanoid Robot Half-Marathon
1/🤯 Robots just beat the human half-marathon world record. And it wasn't even close.
On April 19, 2026, in Beijing's E-Town district, Honor's "Lightning" robot finished a half-marathon in 50:26.
The human world record? 56:42 (Kiplimo).
Robots are now 6 minutes faster than the best human athlete alive. 🏃♂️🤖
#PhysicalAI #HumanoidRobots #AIHardware #TechChina #TechStrategy
https://t.co/jSMInjs8cY
8/ ⚠️ THE THREE BOTTLENECKS
🔋 ENERGY CRISIS:
• Robot consumption: 4-6 kWh per half-marathon
• Human consumption: 0.2 kWh
• Gap: 20-30× human levels
Honor's best: 10.6 km per battery swap (still required 3 swaps for 21 km)
🌡️ THERMAL NIGHTMARE:
• Joint motors: >500W
• Core temps: >80°C without liquid cooling
• Cooling consumes: ~15% of power budget
⚖️ CONTROL INSTABILITY:
• Fall rate: 20% (1 in 5 robots fell during race)
• Sensor drift: ±8 cm
• Terminal control breakdown at extreme performance
#PhysicalAI #HumanoidRobots #AIHardware #TechChina #TechStrategy
https://t.co/9EKUPeFtBv
3/ 🤖 MASS DEPLOYMENT: 300 robots, 87% completion rate
This wasn't a cherry-picked demo:
• 300+ robots participated (+500% vs 2025)
• 105 teams (+425% YoY)
• 26 brands (+225% YoY)
• 87.3% finished the race (vs 30% in 2025)
92 robots successfully completed 21.0975 km.
4/ 🧭 AUTONOMOUS BREAKTHROUGH: 38% fully self-navigating
38% of all teams ran fully autonomous vs <5% in 2025.
That's a +660% YoY increase in autonomous adoption.
Multi-sensor fusion (3D LiDAR + depth cameras + IMU) + BeiDou cm-level positioning = robots that see, think, and react in real-time.
2/⚡THE SPEED REVOLUTION: -68.5% in 12 months
• 2025 champion: 2:40:42 (160 minutes)
• 2026 champion: 50:26 (50 minutes)
• Improvement: -110 minutes in ONE YEAR
That's not iteration. That's a phase change.
For context: The human half-marathon WR improved by 34 seconds from 2018-2020. Robots improved by 110 MINUTES year-over-year
#PhysicalAI #HumanoidRobots #AIHardware #TechChina #TechStrategy
According to both NUS and The Wall Net, the two slabs at UTown are the only Berlin Wall segments currently in Singapore.
The fragments are at NUS University Town, in the garden behind Tembusu College, on a small hillock reached by a tiny path.
#Singapore#Berlin#History
https://t.co/WRmbuC4B8k
Sustainability & Climate Reporting for Business Teams - Chaos to Clarity
📦The biggest climate risk in your company
probably isn’t in your factories.
🌍It’s in your supply chain.
📊And investors are starting to price that in.👇
https://t.co/Ujb1TPbvaW
#ClimateStrategy #sustainabilityspark2026 #Transformation
Dealing with chronic brain fog or headaches? It might be a plumbing issue, not a mental one.
🧠 New case studies reveal "Postural IJV Stenosis"-where forward head posture literally traps blood in the cranium, blocking flow to the heart. Your posture is suffocating your brain. 👇
🛑Stop scrolling for a second. Look at the angle of your neck. At a 60° tilt, your head exerts 60 LBS of force on your spine. That is the equivalent of strapping a standard microwave to your neck. It’s not just "bad posture." It’s structural collapse.
Instant posture fix you can do right now:
✅Axial Extension: Imagine a string pulling your head up.
✅Eye Level Screens: Never look down at a phone.
✅The Reset: Move every 30 mins to fight ligament "creep."
https://t.co/Fw6m0x837V
#Biohacking #healthylifestyle #HealthTech #Neuroscience #Productivity
Four million eyeballs. One #HarryStyles#meme. Three secret ingredients.
This NHS meme didn't stumble into virality—they strategized their way there with: perfect timing + target-audience telepathy + an on-brand call-to-action.
Don't flail around hoping something sticks on IG, this analysis draws upon NHS social media head Joe Freeman's sharing and includes a proposed meme creation framework that balances creativity with care👉https://t.co/HvjQw5LWZ8
🧭Amazon's Working Backwards (WB) is a customer-obsessed product innovation process that begins by imagining the product has already succeeded. Teams draft a Press Release (PR) and FAQ as if launching today, written from the future customer's perspective.
🧭This "working backwards" from the end-state clarifies the vision, kills weak ideas early, and aligns cross-functional teams (product, engineering, design, sales) before heavy investment.
🧭Subsequent steps include mockups, roadmaps, and prototypes, all validated against the PR/FAQ.
🧭WB complements but differs from others by emphasizing pre-development visioning over iteration or empathy gathering.
🧭WB shines in large-scale, complex products (e.g., Echo, Prime Video) where alignment across silos is critical.
🧩Hybrid Potential: Often combined (e.g., WB → Lean MVP → Agile build), but its UVP is preventing "build it and they will come" failures.
#Innovation #ProductDesign #Amazon #AWS
https://t.co/6AmGVPHDAr