Work by @keyi_G@ClaudiaKutter@karolinskainst@scilifelab reveals genome fragility causing 10q23.31 deletion, incl. PTEN, in HAP1 cells, changing profiles resembling those of cancer patients. Stress elevates frequencies, affecting cell readouts https://t.co/7xNS4xuKqM
Amazing highlight of a PhD journey: @keyi_G final task as respondent at her PhD defence! Congratulations Dr Geng! One of the best PhD students one can wish for! It has been such a pleasure and privilege to supervise you! Looking forward to your bright future!
Congratulations to the talented @keyi_G for absolutely acing her PhD defence today, it's been a pleasure co-supervising you! 😄 Looking forward to seeing what adventures await 🎉
Very excited to have the full story from my master thesis out! Keep an eye on how your cell lines behave when using CRISPR-Cas9... Thanks to @ClaudiaKutter and @keyi_G for the opportunity and to all authors for their work!
Be careful with cells you work on. Some of them can sneakly and secretely lose an important piece in their genome to outcompete their peers... Big thanks to everyone contributing to this work!
Pleased to share our latest work showing that CRISPR-Cas9-mediated genome engineering exaggerates genomic deletion at 10q23.31 including the tumor suppressor gene #PTEN: https://t.co/gBppKGJmwc
Wonderful to see our review https://t.co/S3vMDMjweS in press @AJPCellPhys. It's about the astonishing roles of #ncRNAs and RNA-binding proteins #RBPs in liver physiology and metabolic diseases. Great work by PhDstudent @ChrisSommerauer
BREAKING NEWS:
The 2022 #NobelPrize in Physiology or Medicine has been awarded to Svante Pääbo “for his discoveries concerning the genomes of extinct hominins and human evolution.”
If you are struggling with some mysterious observation in Cas9 edited cell, check our work on unexpected on-target effect using a super cool tool in early release! Big thanks to everyone contributing to the work!