Khalid Alshehri

Neurologist interested in Multiple Sclerosis & Autoimmune Neurology.

[Barry Singer MD 🧠 @drbarrysinger]

Ontaneda: First Phase 1 results of off-the-shelf CD19 CAR T-cell therapy (azer-cel) in progressive MS (n=26). No dose-limiting toxicities; EDSS stable/improved in 16/18 at Day 90. Early data; follow-up ongoing. #MSTORONTO2026

[Neurology: Clinical Practice @NeurologyCP]

Corticosteroids are commonly used in the treatment of neuro-oncology patients. However, their benefits must be balanced against the potential development of complications. A recent study set out to provide guidance. Discover what they found: https://t.co/LpEBSg3qPw

[Barry Singer MD 🧠 @drbarrysinger]

Checkout my @ECTRIMS poster. ENHANCE study: #MS patients switching from ocrelizumab to #ublituximab had 69% reduction in wearing-off at week 24. Patients with B cells despite ocrelizumab became depleted on ublituximab. 👉https://t.co/cxqtJKgqKZ #MSTORONTO2026

[Andreu Vilaseca @andreuvilaseca7]

Spinal cord involvement in histiocytic neoplasms is underrecognized, and it's often how the disease first shows up.
With effective MAPK-targeted therapies (BRAF/MEK) available, early diagnosis matters.

In @GreenJournal, we studied 415 patients with ECD, LCH and RDD from the @MayoClinic cohort:
🔹 10% had spinal cord or nerve root involvement
🔹 In 1 of every 2 symptomatic patients, it was the FIRST sign of the disease
🔹 ECD → mainly cord infiltration; RDD → mainly nerve roots or extrinsic compression
🔹 Improvement after treatment: RDD 91%, LCH 67%, ECD only 46%

👉 Think spinal MRI early in patients with neurologic symptoms or high-risk features.

🔗 https://t.co/tSEhAJJQ7m
#NeuroTwitter @Histiocytosis @HistiocyteSoc

[MSJ @MSJ_Research]

A woman in her 20s was referred for demyelinating disease based on white matter lesions on MRI, but was then found to have genetic leukoencephalopathy (LBSL with biallelic DARS2 variants).

Case report from @CLENeurons ▶️ https://t.co/PCxt5Qh4BZ

1/🧵

[العربية @AlArabiya]

استشاري الجراحة والمدير الطبي لمستشفى سليمان الحبيب د. عمر العبيد لـ "العربية": أجرينا 22 عملية جراحية خلال أقل من 24 ساعة للمصابين بالاعتداء الحوثي على مطار الملك خالد الدولي في الرياض

[Secretary Marco Rubio @SecRubio]

The United States strongly condemns the recent attacks on the Kingdom of Saudi Arabia by the terrorist Houthis, including today’s strike on King Khalid International Airport in Riyadh that took numerous innocent lives, including an American citizen.

These reprehensible attacks demonstrate a blatant disregard for innocent civilian life. They must stop now.

We stand with the Kingdom of Saudi Arabia and its people and extend our condolences to the victims and their families.

[JAMA Neurology @JAMANeuro]

Among patients with relapsing #MultipleSclerosis, earlier and continuous ocrelizumab treatment was associated with better long-term relapse and disability control than delayed initiation after interferon beta-1a.

https://t.co/taXdwGVoYy

[JAMA Internal Medicine @JAMAInternalMed]

📑 JAMA Internal Medicine Review: This review provides an evidence-based update on the diagnosis and management of #ShoulderPain to support clinical decision-making and improve patient outcomes.

https://t.co/4RATgJs6pa

[Joe Sabatino @jsabatino37]

T cell immunomonitoring: a comparative analysis of traditional and novel methods to quantify and characterize human antigen-specific T cells

https://t.co/eSjwQfyIn0

[JAMA Neurology @JAMANeuro]

Among patients with relapsing #MultipleSclerosis, earlier and continuous ocrelizumab treatment was associated with better long-term relapse and disability control than delayed initiation after interferon beta-1a.

https://t.co/y1z4fZonDM

[JAMA Neurology @JAMANeuro]

Among pediatric inpatients with unexplained #Neurologic presentations, rapid #WholeGenomeSequencing diagnosed nearly half of patients and changed management in about 2-thirds of diagnosed cases.

https://t.co/fE5GcDtcDT

[Khalid Alshehri @khalidneuro]

@Brandon_Beaber @ParasiteGal I mean god bless him …

https://t.co/NPqNsw6t3g

[Dr. Brandon Beaber @Brandon_Beaber]

patterns of spinal cord injury in multiple sclerosis and other CNS autoimmune diseases. https://t.co/1qRpkuCNRX

[أخبار السعودية @SaudiNews50]

مجلس الشورى:

على جامعة الملك سعود بن عبدالعزيز للعلوم الصحية تطوير جودة مخرجاتها التعليمية في بعض فروعها.

[Nature Rev Immunol @NatRevImmunol]

What the ‘negative space’ tells us about the immunology of multiple sclerosis https://t.co/VeEv1QUmF2

[Practical Neurology @PracticalNeuro]

When should new-onset #seizures raise concern for #autoimmune #encephalitis?

Kelsey M. Smith, MD (@KMSmithMD) and Jeffrey W. Britton, MD (@JeffBrittonMD) review #NMDA receptor, #LGI1, and #GAD65 antibody syndromes, antibody testing, #immunotherapy, and malignancy screening.

https://t.co/ScSjzd7Eip

@AANmember @EpilepsyFdn @AmEpilepsySoc @MayoClinic #Epilepsy #Neurology

[Eoin Flanagan @EoinFlanagan14]

Delighted to share our international review on MRI Characteristics of #MOGAD! ➡️ Key imaging features are highlighted across the brain, optic nerves & spinal cord including lesion dynamics ➡️ Illustrative figures help show its full imaging spectrum👇
https://t.co/TdLM1kg3dS

[Nat Rev Neurology @NatRevNeurol]

New online! Use of MRI in neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein antibody-associated disease — MAGNIMS consensus recommendations https://t.co/2YkWgnCdJY

[Dr.Fernandezcar @DFernandezcar]

▶️SCLC with anti-GABABR, anti-Hu, and no PNS showed distinct molecular profiles.
▶️Anti-GABABR tumors were associated with 5q gain and KCTD16 overexpression.
▶️Anti-GABABR showed B-cell signatures, while anti-Hu showed T-cell/IFN-γ signatures.
👌