Elijah Kirschstein

Ohio State Biomedical Sciences graduate student

[Journal for ImmunoTherapy of Cancer @jitcancer]

New #JITC review: "Cancer-associated fibroblast targeting therapies as a tool to enhance responses to radiotherapy and immunotherapy" https://t.co/ENwjakAr4h

[Anirban Maitra @Aiims1742]

Two cancer associated fibroblast (CAF) papers in #PancreaticCancer
A: In @Cancer_Cell Reticular CAFs (rCAFs) facilitating tertiary lymphoid structures (TLS)
https://t.co/NQblRNScxI
B: In @CD_AACR senescent CAFs (senCAFs) promoting lymph node metastases
https://t.co/5j0NzfXvXc

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

🚨 New publication alert in @Cancer_Cell from @gunderlab & team!

Their study revealed that #myofibroblast programming (the most common fibroblast phenotype in #pancreatic_cancers) transcriptionally represses differentiation into fibroblastic reticular subtypes that are necessary to form #tertiary_lymphoid_structures in #tumors.

Blocking these myofibroblast differentiation signals combined with agonizing lymphotoxin beta receptor reverses this, thereby inducing TLS and promoting anti-tumor immunity.

🧠These findings help us understand how to overcome resistance to TLS formation order to increase response to #immunotherapy.

Congratulations to the team!

Read More: https://t.co/2ytpJvdyMI

@OhioStateSurg @OhioStatePIIO

[Gunderlab @gunderlab]

We published a paper out today in @Cancer_Cell. You can find a short summary here: https://t.co/ddp8KICfiz
https://t.co/R1FIXhRUTO
Congrats to @kirschstein13 and all the authors! @NIH funded research 💪🙏@OSUCCC_James @OhioStatePIIO @OhioStateSurg

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

A remarkable 7th Annual #PIIO Symposium — four sessions of cutting-edge IO science, new ideas, and powerful collaboration.
We wrap with our Awards Session, recognizing excellence in poster presentations and discovery across PIIO. The future of #immuno_oncology is bright. @OSUCCC_James @Zihai @Pelotonia

[Zihai Li, MD, PhD @Zihai]

Impressive talk by @gunderlab highlighting how tertiary lymphoid structures may unlock new therapeutic paths to overcome immunotherapy resistance in #PDAC. @OhioStatePIIO annual symposium 2025

[Pelotonia Institute for Immuno-Oncology @OhioStatePIIO]

👏 Big congratulations to this year’s award winners at The @OSUCCC_James Annual Scientific Meeting — proud to see #PIIO scientists among the honorees! 💪 #ImmunoOncology #CancerResearch w/Monica Venere, PhD; Gaurav Shrestha PhD; Raven Vella; Elijah @kirschstein13

[Gunderlab @gunderlab]

Gunderlab with a great showing at PancMidwest at "TSUN" 😉, and @OSUCCC_James annual scientific meeting. Congrats to @kirschstein13 for winning the top travel award and for Maddie's first poster on B cells in PDAC. Labby hour and eucher to celebrate @OhioStatePIIO @OhioStateSurg

[Gunderlab @gunderlab]

Big congratulations to Elijah @kirschstein13 for passing his candidacy today. Big discoveries in his future on stromal regulation of TLS formation in PDAC. @OhioStateSurg @OhioStatePIIO @TMaceLab

[nature @Nature]

Nature research paper: RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer

https://t.co/dHSd6ErLwP

[Gunderlab @gunderlab]

Hard to have a better first conference experience for @kirschstein13. Awesome job on your talk and congratulations on your young investigator award! @NIH funded research on reprogramming stroma to enhance immune responses in PDAC patients. @OhioStatePIIO @OhioStateSurg

[Cancer Cell @Cancer_Cell]

Plasma cell and cancer stem cell crosstalk in glioblastoma https://t.co/vlbzdhMcyp

[Gunderlab @gunderlab]

Congratulations @kirschstein13, 2nd year BSGP grad student, who was "dialed" for his poster award at the 2024 @OhioStatePIIO symposium, 👏. Big plans for gunderlab in 2025! @OhioStateSurg

[America’s Got Talent @AGT]

It looks like @Kodileerocks just proved to the world that talent is limitless! #AGTPremiere https://t.co/a6MhFICxGq

[Springfield Tigers Baseball @tigerbaseballTP]

Tigers win 11-1! @HenryScheitel with the win! 6 inn, 4 Ks, 1 ER. Also was 2-2!
@ikefink3 was 3-4 w/ 3 RBI!
@5_deck w/ 2 hits, 2 RBIs & a head first slide into 2B.
Mitchell Leonard added 2 hits
@RummelMason and @kirschstein13 w/ a hit a each!
@TigerActivities @mnbaseballhub #woo

[Springfield Tigers Baseball @tigerbaseballTP]

Two wins today vs BLHS!
3-1 and 9-0!
@HovlandNolan with the CG win in game 1 and @kirschstein13 with the CG win in game 2.
The Tigers are now 13-1 and won the Tomahawk Conf. tonight!
Goal #1 ☑️
2 Goals Remain! #notdone @TigerActivities @mnbaseballhub @MinnesotaScores

[Springfield Tigers Baseball @tigerbaseballTP]

Two wins tonight! 13-0 vs GFW and 1-0 vs NUC in a great game! @HenryScheitel throws a CG & gets the W vs GFW! Vs NUC @ikefink3 got the start & went 2. @nolanhovland went 2. @5_deck went 1. @kirschstein13 goes 1 & gets the W! @IvanHovland goes 1/3 & @HMathiowetz 2/3 for the S!

[Tiger Activities @TigerActivities]

Congrats to Eli on receiving the MniAAA Scholarship!

[John Millea @MinnesotaMillea]

At halftime, recipients of the #mshsl Triple A award are honored. They are seniors from around the state who excel in Academics, Arts and Athletics. Congratulations!

[Mr Basketball MN @MrBB_MN]

Mr. Basketball announces its Top 10 list of candidates for the 2019 award. Look for the Final Five to be announced in early March.

https://t.co/qj8C76zbtX