Konstantin Zaitsev

Researcher at JetBrains Research. Gene expression and single cell. Human ageing.

Video games, music and chess enthusiast.

[Alexey Sergushichev @assaron]

I'm happy to present our new web-tool CORESH https://t.co/r1bswFuZXo for searching public gene expression datasets using gene signature as a query, developed by @vd_sukhov, which was just published in @NAR_open https://t.co/PdDMgQz56a 1/n

[Konstantin Zaitsev @konsolerr]

@lisyarus prolly has more to do with your emotion/rewards around problem solving

in the childhood problem solving was more rewarding to me than stressful/forced, so I still feel positively rewarded when I solve puzzles now

[Konstantin Zaitsev @konsolerr]

@lisyarus I would say that the wording "has anything to do" is probably correct, but implication "math olympiads -> disliking puzzles" is probably no so much

Coming from the similar background, I still love a good puzzle game (witness, humanity, golden idol games).

[Konstantin Zaitsev @konsolerr]

@lisyarus community notes - it was in fact 110001 shovels

[Konstantin Zaitsev @konsolerr]

@TheActMan_YT probably in the same folder as elder scrolls 6 is

[Konstantin Zaitsev @konsolerr]

@fransis_ha you had one job

[Konstantin Zaitsev @konsolerr]

@fransis_ha nah, there is grass outside
and I do enjoy touching it from time to time

[Konstantin Zaitsev @konsolerr]

@fransis_ha выполнил месячную норму энгейджмента в твиттере, можно уходить обратно

[Konstantin Zaitsev @konsolerr]

@fransis_ha не говорите мне, что фотография повернута, я не поверю

[Konstantin Zaitsev @konsolerr]

@snpefk Спираченный лайтрум

[Konstantin Zaitsev @konsolerr]

@AleksandrSl28 Ты просто умеешь одеваться

[Alexey Sergushichev @assaron]

I'm happy to share that out paper on Phantasus, a web-application for visual and interactive gene expression analysis, got out in @eLife https://t.co/fd99RQ2nIv Here, I'm using it to analyze a random GEO dataset, including basic QC to filter outliers, in under 100 seconds! 1/n

[Konstantin Zaitsev @konsolerr]

@fransis_ha Да, тоже увидел в списке poor things, и не очень понял, что он там делает

[Konstantin Zaitsev @konsolerr]

@AleksandrSl28 @fransis_ha Главное - это целеполагание. Проснулся с утра, выбрал насилие, и открыл Твиттер.

[Konstantin Zaitsev @konsolerr]

@not_a_reptiloid Герман, хорошо же было, удали твиттер обратно

[Konstantin Zaitsev @konsolerr]

@fransis_ha Вот и тебе денег занесли, кажется, упомянула её в Твиттере...

[Konstantin Zaitsev @konsolerr]

@fransis_ha Мне иногда кажется, что мейджор лейблы уже просто напрямую платят моим друзьям, чтобы они рекламировали мне Тейлор

[Konstantin Zaitsev @konsolerr]

Also kinda cool to see that Sinkhorn transformation is such an easy procedure, and yet, Sinkhorn distances find more and more applications in optimal transport and machine learning

[Konstantin Zaitsev @konsolerr]

Happy to highlight recent preprint by @denis_kleverov, @AladyevaE, Alexey Serdyukov, and @maxim_artyomov

Sinkhorn transformation seems to be the key to much better solve general NMF and fits data into simplexes in both spaces

Read it and have feedback? - share with us!

[Maxim Artyomov @maxim_artyomov]

Happy to report major analytical advance in NMF/deconvolution - we topologically reformulated it as 𝐃𝐮𝐚𝐥 𝐒𝐢𝐦𝐩𝐥𝐞𝐱 problem, reducing it to just K(K-1) variables, K=# clusters/components.

works in scRNAseq/bulk deconvolution, image analysis etc
https://t.co/88jTQothGT