Basal ganglia lab with a focus on neurons, synapses, and circuits in health and mouse models of Parkinson's disease and Huntington's disease. Tweets by Mark.
Bevan Lab: Postdoctoral Research Scientist.
Seeking a highly motivated scientist with expertise and/or interest in in vivo electrophysiology and modern circuit interrogation approaches. Contact [email protected] if interested.
Online now: The cell-surface shared proteome of astrocytes and neurons and the molecular foundations of their multicellular interactions https://t.co/wSaIHdJuo7
Congrats to Kim Reinhold, soon to launch her own group in the Eaton Peabody Labs, on this labor of love. Basically, she shows that the visually recipient zone of the striatum mediates outcome-dependent trial to trial updates of behavior.
https://t.co/kDSBN1yRdf
Thank you so much to @BirnbaumJackie1 and @MunibHasnain for presenting their recent paper today at @CMU_Bio@cmuneurosci
Exciting approach to understand how to explain neural data and movement
https://t.co/oRzThiKjRo
The latest work from the Lammel lab is out today in @Nature!
Discover how changes in neurotensin signaling from the NAc Lat to the VTA lead to food devaluation in a mouse model of obesity 🧀🐭
https://t.co/zGeXCGaHXr
Striatal cholinergic interneurons act at nAChRs to depress #dopamine release, supporting an inverse scaling of dopamine release according to cholinergic activity
https://t.co/s2vdUwdS1v
Proud to have contributed to @JiaxuanQi's masterpiece out @Nature! She shows dopamine transients track the quality of song during juvenile song learning and that dopamine release is driven not just by VTA firing, but by a local cholinergic mechanism! https://t.co/D16ebPe3vP
How much analgesia is needed to manage pain levels in mice after brain surgeries?
A single dose of meloxicam seems to be enough. Even the addition of opioids cannot provide a clear benefit (in line with recent work from others, see refs in our preprint):
https://t.co/Ztrjfybfqj
Science Matters. 🧪🔬🚀
I am alive because of science. We all benefit from science — every day. Science is in our homes, our hospitals, our streets, our work.
For 80 years, science and technology have been a north star for the United States. In 1945, Vannevar Bush’s report to the president of the United States Science, The Endless Frontier called for bold government support of scientific research to drive national security, economic growth, and innovation. This vision led to the creation of the National Science Foundation and to policies ensuring the U.S. leads in science & technology.
Since then, for 80 years, the government has invested in science, fueling discoveries that transformed our health, economy, and quality of life. Science is not a zero-sum game—it creates knowledge, exponential value, innovative industry, and longer better lives.
From life-saving medicine, advanced diagnostics, and disease prevention to AI-driven innovation, space and deep-sea exploration, clean energy, next-generation materials, quantum computing, and precision agriculture, science continues to shape our future.
Science matters. 🔬🌍💡
#ScienceMatters #EndlessFrontier #FutureOfScience
NIH Brain Initiative funded multiple studies on closed loop brain stimulation for a number of neuro/pscyh conditions including Parkinson Disease. Now FDA approval granted for device that adjusts stimulation based on a person's neural activity. https://t.co/qvj6AOHSmy
I am thrilled to share my postdoc work from the Soohyun Lee Lab, https://t.co/iEF9fpTBuZ. Huge thanks to the awesome PI Soohyun Lee and collaborators Yuan Zhao, Ka Chun Lam, @fpereira, and Charles R Gerfen.
🚨📃New Wassum Lab Paper📃🚨
@Jackie_Gio discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇
https://t.co/cjM6W5Apja...
Free full text: https://t.co/sGIdGeC3k8
Coordination between ESCRT function and Rab conversion during endosome maturation
Anne Spang and colleagues @Spang_Lab@biozentrum show that early ESCRT complexes shepherd cargoes towards sites of intraluminal vesicle formation
https://t.co/ghDretQBoM
A comprehensive longitudinal analysis of individuals with preclinical #HuntingtonsDisease identifies #biomarkers of #neurodegeneration and somatic expansion in blood DNA, detectable years before symptom onset. @DrMFarag@UCLHD @UCLIo
https://t.co/3desiwYgKc
@blsabatini@lodder_bart@LinTianPhD Absolute measurements of transmitter levels with fluorescent sensors is a critical, transformative step. Congratulations and thanks to all involved.