Lack Lab

Lack Lab @VanProstateCtr & @kocuniversity

[Lack Lab @lack_lab]

🧬 Funded PhD Studentships – Vancouver Prostate Centre (UBC) 🧬

Join our team to investigate transcriptional regulation in prostate cancer. Two fully funded PhD positions available.

Interested: please send a CV + short expression of interest.

#CancerResearch #PhD #UBC

[Lack Lab @lack_lab]

@CanAztekin Many congratulations Can! Very well deserved.

[Lack Lab @lack_lab]

Passionate about single-cell method development? 🔬 Join our lab as a Postdoctoral Fellow at @UBC and help uncover androgen receptor enhancer mechanisms in prostate cancer.
https://t.co/uKpGrgt6ML

[VCH Research Institute @VCHResearch]

Congrats to this year’s recipients of the VCHRI Top Graduating Doctoral Student & Rising Star Awards! 🎉 Learn how these up-and-coming research leaders are contributing to the community: https://t.co/FAF211BY3d

[Özlem Yedier Bayram @ozlemyedier]

I am extremely honored to receive @WellcomeTrust Early Career Award - the first-ever given to @kocuniversity and Türkiye 🇹🇷! Grateful to my mentors @tugbabagcionder and @Tamer_Onder.It was pleasure working w/@berilesin_ and excited for what’s ahead w/@merdemercann! #WellcomeTrust

[Tugba Bagci Onder @tugbabagcionder]

Huge congratulations to @ozlemyedier for receiving the early career award from @wellcometrust to further explore the mechanisms behind epigenetic regulation of cell cycle. I wish her and @Tbo_Lab members success in this exciting project👏

@kocuniversity @_KUTTAM_

[Nada Lallous @Lallousnada]

Check out our bioRxiv preprint summarizing our work on AR-V7 condensates, their role in activating a specific gene signature, and enhancing its expression in CRPC models. This work, led by post-doctoral trainee @ShabnamMassah, benefited greatly from co-authors and collaborators.

[Vancouver Prostate Centre @VanProstateCtr]

VPC is thrilled for the launch of the Mohseni Institute of Urologic Sciences! This significant leap forward will foster innovation and enhance translational research for many urologic conditions to positively impact patients. https://t.co/30vWpc6axl
@VCHResearch @VCHhealthcare

[Anirban Maitra @Aiims1742]

Core facilities are truly one of the most undervalued assets in an academic institution. They are often treated as also rans, staffed by non tenured faculty with little leeway, and given an exceedingly short runway to become profitable.
In an age of shrinking lab sizes and astronomical maintenance contracts, cores will increasingly become the engines that fuel research. Institutions have to invest in core facilities in order to spur innovation and efficiency, and expect some will be a “loss leader” on revenues, with intangible returns on research productivity.
For those on the job market, getting to know the institutional core facilities and directors should be an indispensable part of the recruitment process. Talk one to one with some of the core directors. How institutions approach core facilities is a huge “tell” on institutional research ethos.

[Lack Lab @lack_lab]

@LambAlastair @GSTTnhs @GuysUrology Very exciting news!

[Lack Lab @lack_lab]

@Lallousnada @janefoofoo Many congratulations!

[Lack Lab @lack_lab]

@MDershewitz Hi Matthew - great question. Although it's outside the scope of this work, it’s unlikely that AR expression can be easily modulated epigenetically, as most tumors have somatic mutations that increase AR copy number. These hard-wired mutations often drive AR expression in CRPC.

[Lack Lab @lack_lab]

@f_hach, @dogancan, @AdelmanLab and Matt Freedman

[Lack Lab @lack_lab]

How does AR activation affect gene expression? Our new paper shows it’s less about creating new loops and more about amplifying contact frequency in existing ones. Explore in @NatureComms (https://t.co/LozFmiNyni) Tweetorial below: #AR #Epigenetics #prostatecancer

[Lack Lab @lack_lab]

@CFCE_DanaFarber Deeply grateful to our amazing collaborators who brought this research to life! From data generation to analysis, everyone’s unique expertise was essential. This work shows what team science can accomplish when we come together with a shared goal to improve cancer understanding!