I'm excited to share my manuscript describing our new insights into how Notch signaling induces transcription of target genes. Thanks to @BlacklowLab and @AdelmanLab and all co-authors!
https://t.co/AqTKM5SedS
Congratulations Emily and all authors! It’s great to see such a clear role for NELF-mediated RNAPII pausing in spermatogenesis. Thanks to Prabu for introducing us to this cool system!
Happy to announce the final version of our paper is now available @NatureComms!
https://t.co/a9iZjZUX8P
Thank you to co-authors Kavya, @geoffmnelson@hdzomer, Debarun, Irene, Reza, Huanyu, @AdelmanLab and Prabu for a great collaboration of transcription and development expertise!
A team led by Ludwig Harvard’s Karen @AdelmanLab has discovered why drugs targeting SWI/SNF, a protein complex that's mutated in 20-25% of cancers, don't always work as expected—and shown in cell culture studies how such resistance might be overcome. https://t.co/kNKTucNwlU
We have a great lineup of speakers for the the @CEEHRC annual meeting, featuring 2 exciting keynotes this year.
Michael Taylor from @TexasChildrens@bcmhouston
Karen Adelman @AdelmanLab from @harvardmed who is our Trainee Keynote for this year!
https://t.co/dSIWp819yb
Such great news! Congratulations to two amazing scientists, Eva Nogales @NogalesLab and Patrick Cramer @CramerLab who have changed our understanding of transcription with their beautiful structures! 🎉
The #ShawPrize in #LifeScienceAndMedicine 2023 is awarded in equal shares to Patrick Cramer and Eva Nogales for pioneering structural biology that enabled visualization, at the level of individual atoms, of the protein machines responsible for #genetranscription.
#ShawPrize2023
Managed to catch-up with the truly amazing Karen Adelman @AdelmanLab before leaving Boston for Philadelphia. So much science, family and football to discuss. With perhaps a cheeky glass of port.
Great to see the conclusions from a recent paper from our lab (Stein et al 10.1016/j.molcel.2022.10.004) so nicely recapitulated in a different system !!!