Apoorva Baluapuri

Walter Benjamin Research Fellow @AdelmanLab @harvardmed; PhD @_WolfLab @Uni_WUE.

[Apoorva Baluapuri @Pol2Runner]

Thrilled to see my postdoc work @AdelmanLab on the Integrator (INT) now out @CellCellPress:We found that INT deficiency allows immature and unlicensed RNAPII to precociously enter genes. This immature RNAPII can transcribe short genes but terminates prematurely in long genes

[Harvard Medical School @harvardmed]

A new study shows mutations in the Integrator complex — linked to cancers, blood disorders, neurodevelopmental abnormalities, and other diseases — cause chronic stress in cells https://t.co/A8mBpJuFao

[Apoorva Baluapuri @Pol2Runner]

Thanks to @Wagnerlab_RNA @khurana_lab and SchafferLab for the awesome collaboration that made this work possible! #RNA #StressResponse #RNA #GeneReg #stemcells #Genomics #GeneRegulation Check out the paper here: https://t.co/hBtMQDAuKb.

[Apoorva Baluapuri @Pol2Runner]

Thrilled to see my postdoc work @AdelmanLab on the Integrator (INT) now out @CellCellPress:We found that INT deficiency allows immature and unlicensed RNAPII to precociously enter genes. This immature RNAPII can transcribe short genes but terminates prematurely in long genes

[Apoorva Baluapuri @Pol2Runner]

Amazing to see how this work connects defects in transcription elongation to chronic stress signaling and disease! Could targeting dsRNA or ISR pathways offer new therapeutic strategies for conditions caused by INT mutations? Fascinating implications for RNA biology and medicine!

[Apoorva Baluapuri @Pol2Runner]

Excited to be at @KeystoneSymp for first time ! Looking forward to plenty of science&fun at #Epigenetics in #Development and Disease #KSEpigenetics25 https://t.co/LRoXAJgEzF #RNA #GeneReg #GeneRegulation

[Ernst Schmid @ernstschmidd]

Very excited to share that my thesis work is out in Molecular Cell! We trained a Structure and Omics informed Classifier (SPOC) to score binary AlphaFold multimer (AF-M) predictions by structural quality and consistency with experimental omics datasets. https://t.co/Y9OIphtAv9

[Apoorva Baluapuri @Pol2Runner]

Join organizers @AdelmanLab, @helin_kristian to discuss emerging research @KeystoneSymp #Epigenetics in #Development and Disease #KSEpigenetics25 https://t.co/LRoXAJgEzF

[Dr. Stuti Mehta @StutiMehtaR]

Delighted to share our #NightScience tale: "A tetramer of BCL11A is required for stable protein production & fetal hemoglobin silencing," in @ScienceMagazine. Co-led by Zheng Ge, Yin Maolu, & me, here’s a tweetorial about our puzzle-solving adventure! 1/7 https://t.co/ZJvFCklgtP

[Apoorva Baluapuri @Pol2Runner]

@hilgers_lab Congrats, Valérie - great news !! Looks like an amazing end to the year and a great start in Basel. Looking forward to the nice stuff that will come of it :)

[Hilgers Lab @hilgerslab.bsky.social @hilgers_lab]

Very proud to have been awarded an ERC Consolidator grant for research on neuronal RNAs! Rock on, team!

[Apoorva Baluapuri @Pol2Runner]

@TychoMevissen @CellCellPress Great to see this in print !! Congrats to you and the team!!!!

[Apoorva Baluapuri @Pol2Runner]

@DimitriosRNA @ERC_Research @MYCGyvers Great news !!! Congratulations 🎉🎊🍾

[Apoorva Baluapuri @Pol2Runner]

@bmart87 Godspeed !!!

[Apoorva Baluapuri @Pol2Runner]

@kaymakirrm @DrRGJonesLab Congrats on the new addition to family and pubmed :)

[Kinga Kamieniarz-Gdula #StayWithUkraine #NCNtoTlen @STOPlabPI]

Looking for an exciting #PhD project in #molecularBiology? How about this question: what determines a gene's end? Most human genes have alternative ends, the choice of which is important for health and disease. Yet we still don't understand how this choice is made!

[Apoorva Baluapuri @Pol2Runner]

@anshulkundaje Less drama, better feedback, fruitful conversations : what’s not to like 🤓

[Apoorva Baluapuri @Pol2Runner]

@_WolfLab Congrats @MV4_11 @NevenkaDudvars1 for the really nice work - great to see both histone remodelers and chaperones (SPT6) from MYC interactome in the both genetic dropout screens. A real tour de force....!

[Apoorva Baluapuri @Pol2Runner]

@MYCGyvers @_BurgerLab 10 points to Slytherin !!

[Apoorva Baluapuri @Pol2Runner]

@DimitriosRNA @MolecularCell @seyvos @belilab @maric_hans Good one, sir !! Congrats to everyone :)