Laura Castilla-Vallmanya

Postdoctoral Researcher in Molecular Neurogenetics laboratory 🧠🔬PhD in Genetics 🧬 Molecular human genetics and neurodevelopment.

[Lund Stem Cell Center @Lund_Stem]

📰 A recent @NatureComms study by a @Lund_Stem team led by @ch_douse reveals how DNA methylation & the HUSH complex work to silence repetitive #DNA and protect genomic stability, providing new insights for #aging and disease research.

Read more ⤵️
https://t.co/2FhXPTBohc

[Johan Jakobsson @JakobssonLab]

We started the academic year by discussing transposons for two days at the beach! Lots of new data soon coming your way… @Lund_Stem #TEs #transposons

[Vivien Horvath @VivienHorvath8]

I am thrilled to see my first postdoc paper published in @NatureSMB! 🌟🧠🧬

“Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease”

https://t.co/cJenBgokfl

1/n 🧵

[Laura Castilla-Vallmanya @lcastilla30]

Huge pleasure to have contributed to this amazing work! Beautiful story about epigenetics, SVAs and neurodegenerative disease 🧬🧠

[Johan Jakobsson @JakobssonLab]

Our study on XDP, SVAs, ZNF-91 and heterochromatin has now been published in @NatureSMB.

"Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease"

https://t.co/trbB8Y8U8i

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[Johan Jakobsson @JakobssonLab]

On my way to #eshg24 in Berlin. See you there! Two oral presentations from the lab:

[Laura Castilla-Vallmanya @lcastilla30]

Are you at #eshg2024 and want to know more about TRIM28, transposable elements and neurodevelopmental disorders? Come to my talk today at 18:45h in the “Novel genes in neurogenetic disorders” session 🧠🧬 @JakobssonLab

[Johan Jakobsson @JakobssonLab]

We are recruiting! We are looking for new members (postdocs and/or bioinformaticians) to join our team. Translational projects on neuroinflammation, transposable elements and single cell analysis. Email or DM me for more info! @Lund_Stem

Please RT!

https://t.co/YZiOM2GROs

[Christopher Douse @ch_douse]

Ana Pombo @apombo1 kicking off a fabulous line up of international speakers at our Segerfalk neuroepigenetics symposium this morning. @JakobssonLab @LabRowe @marekbartosovic @sumrubayin @TomohisaToda @VivienHorvath8. Also a beautiful day in Lund!! 🌸🌸🌸 @Lund_Stem @medfak_LU

[Christopher Douse @ch_douse]

Wonderful keynote talk by @lab_schaefer at Lund Neuroscience day about microglia neuron interactions. Several new and provocative concepts (in a good way). Beautifully designed experiments with absolute clarity of purpose and crystal clear delivery.

[Vivien Horvath @VivienHorvath8]

We had a great time at #UniStemDay2024 with Raquel Garza and @aniada97 showing to highschool students how we use nanopore sequencing in our lab to study the contribution of transposable elements to neurodegenerative disorders. 🧠🧬@nanopore @UniStemDay @JakobssonLab

[Laura Castilla-Vallmanya @lcastilla30]

Always exciting and rewarding to share what we do in the lab with the new generations. Hopefully we even managed to inspire some young brains! So happy to be able to participate in #Unistemday2024 🧠🧬🔬@Lund_Stem @UniStemDay

[Patricia Gerdes @Patricia_Grds]

We had a great time at #UniStemDay2024 explaining to high school students how we study human brain evolution using human and monkey brain organoids and looking at gene expression 🧠🐒🔬🧬 @lcastilla30 @NPandiloski @Lund_Stem @UniStemDay

[Johan Jakobsson @JakobssonLab]

Why does not everyone work on transposons?

[Kelly Rabionet @krabionet]

We are a highly collaborative group exploring the #molecularbasis of ultrarare #neurodevelopmental disorders, using #neuronal & #organoid models. If you want to join our research group & make a difference in #TRAF7 or #SchaafYang syndromes, check the #BeatriudePinós & contact us

[ASAPTransposons @ATransposons]

Team Jakobsson having another in person meet-up in the Big 🍎to discuss all the great science going on. #throwbackthursday @ASAP_Research

[Laura Castilla-Vallmanya @lcastilla30]

@ch_douse Exciting to learn new things from a protein expert 🤓🧪

[Christopher Douse @ch_douse]

Open position(s) in my group @Lund_Stem to investigate genomic repeats in human brain development and degeneration.

There's just so much cool biology to discover here and we now have the tools to get started...

Thank you to @cziscience for funding!

[Johan Jakobsson @JakobssonLab]

@Patricia_Grds opens the @JakobssonLab and @ch_douse labs L1-workshop. An afternoon full of LINE-1 discussion and debate…

[Johan Jakobsson @JakobssonLab]

New paper from our lab - Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia.
@CellReports @Lund_Stem
https://t.co/VeHKYTl9kl

[Lund Stem Cell Center @Lund_Stem]

🎉The @Lund_Stem Annual Retreat 2023 was a smashing success! We had an amazing time connecting with fellow researchers & discussing the latest in #stemcell #research in Båstad, Sweden last week! (1/4)

Check out our video capturing the event's most memorable moments!👀👇#LSCC2023

[Johan Jakobsson @JakobssonLab]

We spent two days in 🇭🇺 visiting the lab of @kpircs . Fantastic days full of discussions around neurodegeneration, transposons and autophagy.