Excited to present our new preprint: Topoisomerase IIb binding underlies frequently mutated elements in cancer genomes: https://t.co/fOqYGSI1Ah. TOP2B ChIP to analyse non-coding drivers & mutational processes in 6k cancer genomes +in vivo validation of RMRP locus as a new driver.
Happy to share our review paper on the role of topoisomerases TOP2A & TOP2B in transcription and cancer w/ @wilson_md, published today @ScienceAdvances. We discuss recent findings of TOP2 in genome regulation and carcinogenesis https://t.co/cUdqdW6ywi
A special thank you to our anonymous reviewers for their very positive and constructive feedback, our colleagues from the topoisomerase community, @reimand for invaluable discussions and comments, and @SRC_CRS for support.
@TraverHart Well...someone might need placentas for their PhD projects :D so instead of putting it in this freezer or taking it home, placenta could be donated for research :)
Today for #GivingTuesday, I'm supporting
@SRC_CRS. Together, we can outsmart cancer. Visit https://t.co/kEaugvz3ze to make a donation and support cancer research. #everydaycancerhero
Cancer doesn’t take a break. Research can't either. I am grateful to @SRC_CRS for the Next Generation of Scientists grant that supports our research on the molecular mechanisms of liver cancer.