Longevity Wiki

Open Science Education on Longevity. Non-profit & open-source platform to democratise and centralise information on Aging. Search for a longevity topic👇

[Longevity Wiki @longevitywiki]

We are growing! We are looking for contributors to write new articles on Longevity Wiki. Contact us on Twitter by DM or at https://t.co/80ZoYD09h2

[Longevity Wiki @longevitywiki]

@CJHandmer @JoanneZPeng There have been attempts at screening for essential genes in E. coli and in vitro @iaincheeseman lab put out this very useful resource on the phenotypes of >5K essential genes https://t.co/37xTWjURnc

[Joanne Peng @JoanneZPeng]

this (@longevitywiki) is well-written and deserves many more eyes and scientists contributing!

https://t.co/7QGKQYPiL2

[Longevity Wiki @longevitywiki]

The @DogAgingProject, led by @mkaeberlein and @DPromislow, is an ongoing study tracking tens of thousands of companion dogs in the US to find factors contributing to aging. As part of the project, #rapamycin is also being tested in dogs: https://t.co/MKFNXrRNOK #longevitywiki

[Hongjie Li @HongjieLi5]

Our Aging Fly Cell Atlas is out. Do different cell types age at the same rate? No. Which cell types age faster? Fat, liver and muscle. Which cell types age slower? Neurons. Great collaboration with @StephenQuake @HenriJasper @mariabrbic @TzuChiaoLu

[Longevity Wiki @longevitywiki]

Serum albumin is an important biomarker of #aging, according to deep-learner predictors of biological age. A study performed by an insurance company has shown that levels of serum #albumin might be predictive of overall mortality. Learn more at:
https://t.co/0YVXgKzPDy
#LONGEVITY

[Longevity Wiki @longevitywiki]

#Rapamycin is the gold standard longevity drug, but #Isomyosamine has markedly outperformed rapamycin in a mouse longevity study! Can these results be replicated in other models? Learn more at:

https://t.co/1jL435cOKb

#longevity #longevitywiki #aging #lifespan

[Longevity Wiki @longevitywiki]

#Telomeres are DNA fragments that cap and protect the ends of chromosomes. Telomere shortening progresses with age and is one of the #HallmarksofAging. Several anti-aging therapies exist targeting telomeres. Learn more at: https://t.co/yIc2hnFzyi #longevitywiki #longevity #aging

[Longevity Wiki @longevitywiki]

Looking for the latest articles on Longevity Science? Check out what Longevity Wiki has to offer at:

https://t.co/YzWBSJbXag

#longevity #longevitywiki #aging #lifespan #lifescience

[Longevity Wiki @longevitywiki]

#CASIN is a selective inhibitor of Cdc42. During aging, higher expression of Cdc42 can be used as a predictor of higher risk of mortality. CASIN has shown to rejuvenate HSCs in vivo. Learn more about its mechanism and side effects at: https://t.co/PtPkFOCj62

#longevitywiki

[Longevity Wiki @longevitywiki]

Mitochondrial dysfunction, and especially dysfunction of mitochondrial dynamics, is considered a hallmark of aging and has been implicated in many age-related diseases. Learn about mitochondrial dynamics in aging at:
https://t.co/jRIhOGMjER

#longevity #aging #lifespan

[Longevity Wiki @longevitywiki]

Which is your favorite theory of aging?

#aging #LONGEVITY #lifspan #lifescience

[Longevity Wiki @longevitywiki]

The health benefits of #coldexposure has been a hot topic of controversy recently. What are the known healthspan and lifespan effects from activating cold-shock proteins, a type of hormesis mechanism? Find out at:

https://t.co/PXYa9hgs5b

#longevity #aging #longevitywiki

[Longevity Wiki @longevitywiki]

Just stumbled upon this fascinating article on @Telegraph revealing that dogs age seven times faster than humans! 😱 But, new research is underway that could potentially extend their lifespan!🙌

https://t.co/GDB1Py5OAR

#Longevity #aging #lifespan #dogs

[Longevity Wiki @longevitywiki]

Activating transcription factor 4 (#ATF-4) is required for the lifespan extension of mTORC1 inhibition (target of #rapamycin) and of translation inhibition, and cooperates with over key longevity transcription factors. Learn more about this protein at:

https://t.co/bWO6Q60vhn

[Longevity Wiki @longevitywiki]

Longevity Wiki is a non-profit that provides a central space that allows multiple contributors to create high-quality articles that are accessible to a broad audience! To maintain the Wiki, we rely on our donor's. Contribute today at:
https://t.co/JnhLmwKRDQ

#longevity #aging

[Longevity Wiki @longevitywiki]

Heat-shock response is a result of exposure to elevated temperature, in which cells activate various protective mechanisms. This response is mediated by heat-shock proteins. What role do heat-shock proteins play in the aging process? Find out at:https://t.co/5tDknOg7pK
#heatshock

[Longevity Wiki @longevitywiki]

Resveratrol is produced by some plants after injury or infection. Numerous experiments have investigated the lifespan & healthspan effects of #resveratrol across species, carrying conflicting results. Where is the science now? Find out at: https://t.co/8SOB2D0TMm #longevitywiki

[Longevity Wiki @longevitywiki]

Did you know that Longevity Wiki is also on LinkedIn? Follow us there for more great Longevity content! 👇

https://t.co/scenY11iEm

#longevity #aging #lifespan #mortality #LifeScience

[Longevity Wiki @longevitywiki]

Research has shown that there are significant differences in longevity between the castes in many social insect species. Can this provide a useful model for understanding the epigenetic pathways & mechanisms that influence aging? Find out at:
https://t.co/Vsq4UO5wSZ
#LONGEVITY

[Longevity Wiki @longevitywiki]

Advanced glycation end products (AGEs), also known as glycotoxins, are harmful oxidant compounds that result from a sugar being added to proteins or fats. Animal-derived food & dry heat for cooking leads t higher production of AGEs. Learn more at:
https://t.co/waLDwzVg1f

#aging