Lasse Toftdal Dynesen @ltdynesen.bsky.social

Mostly antibodies and B cells, some zoonotic retroviruses 🧬🦍🦠 Post Doc @SymphogenAS. Past: PhD @institutpasteur, MSc @SSI_dk @SyddanskUni he/him 🇩🇰🌈🍉

[Lasse Toftdal Dynesen @ltdynesen.bsky.social @LTDynesen]

🥳Pleased to share the early online version of our new study out @PLOSPathogens https://t.co/0HC5utAUIS which forms the major work from my PhD @PasteurVirology. Below a deep 🧵 on our study on neutralizing antibodies from gorilla simian foamy virus infected individuals 👇 (1/n)

[Olivier Schwartz Lab @Virus_Immunity]

An interesting model based on PBMC embedded in a collagen-based matrix under perfusion within a microfluidic chip. The system promotes amplification of Ag-specific memory B cells and neutralizing antibody production. @JExpMed
https://t.co/9UhizfvwvG

[Prentoe_Lab @Prentoe_Lab]

https://t.co/KTSGUzJXgy

Turns out the HCV glycoproteins form homodimers! Congrats to everyone involved in this team effort, especially Elias and Christina! Thanks to
@lundbeckfonden
@UCPH_BRIDGE
for financial support.
@Nature
@augestad_elias
@CHOlesen
@kaituowang
@mAbgician

[Nolwenn Jouvenet Lab @lab_jouvenet]

Archaeovirology in the lab
sequencing of Polioviruses stored for more than 60 years in a sealed box unlocked some mysteries
DOI: 10.1093/ve/veae063

[Lasse Toftdal Dynesen @ltdynesen.bsky.social @LTDynesen]

Had a great time presenting my research for a second time at the annual #SeedPods day as part of my Post Doc in the #SHINEDocs community :)

[Servier @Servier]

🤩 We were pleased to welcome around forty five talented young #scientists of our #SHINEDocs #community for the #SEEDPODSDay.
They presented their research projects in 3 min in an easy-to-understand way. The objective? To accelerate #research and #innovation to benefit #patients.

[Crìsdean MacEanraig @NosrednehTemple]

The Lancet estimates that the direct and indirect death toll of the Gaza genocide could be as high as 186,000 people

[BogunovicLab @BogunovicLab]

Latest from us. How a rare genetic disorder inspired a broad spectrum antiviral drug. Started by @JustinTaft12 continued by @roosheelpatel and Dr. Akalu in our lab. @KidsAtColumbia @SinaiImmunol @IcahnMountSinai @Columbia https://t.co/LvebpMIhie

[Edward Nirenberg 🇺🇦 @ENirenberg]

There's a new preprint out that has some really important findings regarding the immunity elicited by mRNA vaccines:
https://t.co/MobKIS2Fl6

But... it's more complicated than it seems.

[Lasse Toftdal Dynesen @ltdynesen.bsky.social @LTDynesen]

More amazing work by my former colleagues on the always fascinating Foamy viruses :) congrats Ignacio, Marija and everybody involved! 👏🏼🌟🦠

[jonatcoquet @jonatcoquet]

A joy to read these two papers today identifying a memory B cell primed for production of allergen-specific IgE. Well done everyone! Well done @jfekoenig
https://t.co/GLTzpveVz9

[ScheelLab @ScheelLab]

Still a few days left to apply for a virology Postdoc in Copenhagen!

[Lasse Toftdal Dynesen @ltdynesen.bsky.social @LTDynesen]

@marija_backovic Congrats Marija!! 👏🏼

[Ria Lassauniere @Ria_Lassauniere]

Our live virus SARS-CoV-2 studies from Denmark suggest that the level of BA.2.86 plasma neutralization is mostly comparable to that of XBB.1 and EG.5.1.

Similar to live virus studies from @sigallab and pseudovirus studies @BarouchLab @ShanLuLiu1 @SystemsVirology

[ImmunoPasteur @ImmunoPasteur]

Apply to the Pasteur-Paris University International doctoral program (PPU) and join one of our amazing labs! Several projects are available this year at @miupasteur @Peduto_lab @MOUQUETHugo1 and P.Bruhns's lab
More info here https://t.co/oDfyCZMK3I

[Lasse Toftdal Dynesen @ltdynesen.bsky.social @LTDynesen]

@Timothee_B @PasteurVirology @anr Congrats Tim!!

[ScheelLab @ScheelLab]

Excited to share our labs first @Nature paper! In collaboration with @VintherLab we show that hepatitis C virus #RNA is capped with FAD protecting it from innate immune sensing. https://t.co/mc6rwaRHId Congrats Anna Sherwood and Lizandro Rivera-Rangel 👏🏻🍾 #HCV @UCPH_health

[Lasse Toftdal Dynesen @ltdynesen.bsky.social @LTDynesen]

I want to send my gratitude to everybody involved in this project, especially my former lab members in the EPVO unit at @institutpasteur, friends and collaborators @marija_backovic and Ignacio Fernandez and all funding agencies including the PPU PhD program! Merci 🦠🦍🥳🇫🇷 (end)

[Lasse Toftdal Dynesen @ltdynesen.bsky.social @LTDynesen]

🥳Pleased to share the early online version of our new study out @PLOSPathogens https://t.co/0HC5utAUIS which forms the major work from my PhD @PasteurVirology. Below a deep 🧵 on our study on neutralizing antibodies from gorilla simian foamy virus infected individuals 👇 (1/n)

[Lasse Toftdal Dynesen @ltdynesen.bsky.social @LTDynesen]

If you made it here (I’m impressed 😂): Future work may precisely define these nAb epitopes through cloning of human monoclonal antibodies (no neutralizing mAbs exist today) and other antiviral antibody effector functions could be investigated (25/n)