Orange passion fruit stays fresher longer than more popular purple varieties, according to new @ufhorticulture research ➡️ https://t.co/KKXhJDNktz
Now, @UFPlantbreeding can use the markers they discovered to develop longer-lasting purple fruits.
Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from transgene expression and real-time fluorescence to modulation of innate cell behavior (excitation or inhibition of neurons, induction of cell migration, etc.)?
Today we report in Nature a new technology platform that provides a step in that direction: PAGERs, for Programmable Antigen-gated G protein-coupled Engineered Receptors, convert recognition of extracellular soluble or cell-attached antigens into diverse user-selected responses. PAGERs are based on G-protein coupled receptors (GPCRs), which themselves are not structurally modular, but we were able to build in modular antigen gating by fusing an antagonist peptide to the extracellular N-terminal end, and then gating the antagonist with a fused antigen-binding nanobody. When antigen binds, it sterically interferes with the antagonist, leading to relief of receptor inhibition. Drug or agonist can then turn on PAGER.
https://t.co/Clt8yjyk2y
New work reveals the impact of anxiety & depression on PhD students.
"Anxiety and depression can have a substantially detrimental impact on graduate students’ experiences [..] and likely also contribute to increased time to degree and student attrition."
https://t.co/iNitLTuagj
Congratulations to our 2024 Genetics Society medal winner, Robert Martienssen. Rob is sharing his work on Germline small RNAs, the triploid block and the drive for maize domestication #GSTransposons@CSHLplants
Excited to announce the 2024-2025 Global Fellows!
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These early-career researchers are tackling global challenges through international collaborations.
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Read about them here: https://t.co/oecwB6dvz6
Freaky Flowers Volume 3!🌸🧬
Did you know that just a few mutations can transform the Arabidopsis flower into all kinds of forms? 🤯
Here’s a tour of 6 mutants that orchestrate floral development and architecture 🧵
Today, we remember the incredible life and legacy of HHMI Investigator and pioneering plant biologist Joanne Chory of the @salkinstitute. A devoted researcher, colleague & mentor, Joanne has had a profound impact on science and all of us who knew her.
Read more about Joanne’s legacy: https://t.co/587yt6ufoR
My department has two open Asst. Prof searches:
Plant Systems Biology or Biotechnology (https://t.co/uE9UgP21Vg)
and Translational Plant Sciences (https://t.co/paI5g0ugoZ).
Arthur Grossman is Carnegie Science's newest member of the National Academy of Sciences. We sat down with him to discuss his wide-ranging research program and the philosophy that's resulted in decades of groundbreaking plant science. https://t.co/QEDo2u6L35
Job alert 📢
We are looking for a new Independent Junior Group Leader in plant molecular biology @ZMBP_Tuebingen!
Submit your application by December 8th as a single pdf
Please RT
#plantscijob#JuniorPI
@UFRootBioLab Hey Lorenzo, it’s unfortunate that you’re leaving, but I wanted to wish you the best of luck in your new position. I know you'll do great, and I’m sure exciting opportunities lie ahead for you. Keep in touch! Tie
Integrating the Study of Polyploidy Across Organisms, Tissues, and Disease. Annu Rev Genet. 2024 Sep 3. doi: 10.1146/annurev-genet-111523-102124.https://t.co/Q6PP7p17PX
The Biology Dept at UMass Amherst is hiring (again!). We have TWO TT faculty positions: Developmental Cell Biology and Plant Biology. Please share and apply!
https://t.co/D8AfmwsGHi
https://t.co/k2qo1HAsZ4
https://t.co/ofsQ9R0kn5
Deadline for applications is 30th September 2024, and the call is restricted to researchers with 2–8 years postgraduate/postdoctoral experience, excluding periods of leave.
#ECR#internship#PlantScience
https://t.co/UQa3Iil2T9