melissa j martin

Research scientist @WRAIR AMR genomic surveillance. MSc & PhD @LSHTM @SangerInstitute, PostDoc @MassEyeandEar @HarvardMed, @KlebClub fan!

[melissa j martin @luluScience]

Many years in the making - thrilled this is submitted! Convergence is driven by the acquisition of iuc and rarely results in phenotypic virulence. Complete with a one of a kind global Kpn plasmidome landscape and collection !

[Francois Lebreton @Fr_Lebreton]

New preprint out! @AnjaliSapre @luluScience and co. mapped the evolutionary routes of convergence in K pneumo. Pop analysis of >1,400 global genomes & 7,500 closed plasmids to see how #AMR & virulence genes come together and impact phenotypes. https://t.co/VmUymZyskh

[melissa j martin @luluScience]

Thank you, Dr. Lee. It was great to share our work with the kleb community!

[Dr. Amy Lee @minisciencegirl]

Brilliant talk from .@luluScience on profiling plasmids of global collection of Klebsiella pneumoniae to understand how resistance and virulence genes converge in a strain. #KLEBS2024

[guido werner @guwe33]

Starting day 3 of #KLEBS2024 with a session on Genomics and Evolution with excellent presentations given by @daanensen , @OlayaRendueles , @luluScience , @bananabenana , Anna Weber

[melissa j martin @luluScience]

Can’t wait!

[Sylvain Brisse @sylvainbrisse]

Smells like KLEBS spirit #KLEBS2024

[Olaya Rendueles @OlayaRendueles]

Really excited to meet the #Klebsiella community in person! Thanks @sylvainbrisse & co for making this happen!

[Rob Kingsley @DrRobKingsley]

Training workshop for our collaborators @NMRL Zimbabwe funded by @gatesfoundation to investigate the association of #typhoid with protists in wastewater but will have a positive impact for surveillance including #AMR Thanks to @tapfumamashe, @tweakyaustin, Michaela and Petros

[Mario Feldman @MarioFeldman9]

We are hiring two Assistant Professors!! Great place to work and live!

[Francois Lebreton @Fr_Lebreton]

Our new paper with Tom Russo’s lab is out in @eBioMedicine We took out individual genes, combinations, or the whole virulence plasmid to measure their relative contribution in K. pneumoniae hypervirulence #hvkp @KlebClub https://t.co/LSmJxJBKN4

[The Lancet Microbe @LancetMicrobe]

New review article

WHO global research priorities for antimicrobial resistance in human health

https://t.co/veDTyECs7D

#AMR #OpenAccess #OA

[melissa j martin @luluScience]

Looking forward to this one!!

[Klebsiella Papers @KlebsPapers]

Plasmid-chromosome transcriptional crosstalk in multidrug resistant clinical enterobacteria https://t.co/V0pZYZYuvv

[melissa j martin @luluScience]

Fantastic course, networking opportunity, and location! Highly recommend !!

[Francois Lebreton @Fr_Lebreton]

Registration for the 2024 (Oct 19-27) ICARe course https://t.co/QecUntfSPS is open until July 28. Be 1 of 40 selected participants and join Patrice Courvalin, @Faecal_flora, Heinz Moser and 30+ experts on #AMR and #drugdiscovery for a full week in #Annecy
https://t.co/QecUntfSPS

[Francois Lebreton @Fr_Lebreton]

This is great paper and but I got to admit (though I am biased of course) not a single mention of the work done by DoD within the National Action Plan CARB program is a bit disappointing…

[Travis Kochan, Ph.D. 🧬🦠🔬🧫 @TKochanPhD]

I am very excited to share my newest article on virulence of #Klebsiella pneumoniae clinical isolates published today in @NatureComms. A big thank you to all of my co authors for their hard work! Including 5 grad students and 4 undergrads. #Microbiology

https://t.co/WWGvMlgDAB

[Ozan Gundogdu @OzanGundogdu11]

Fully funded PhD opportunity in my team; part of
@LSHTM, @NU_kouhou collaboration with Dr Daniel Inaoka and Prof. Toshio Kodama at Nagasaki Uni (https://t.co/rjQE1my5fk) dissecting the functions of the Campylobacter jejuni Type VI Secretion System (T6SS) effectors 🦠☕️🥼🧫👩🏾‍🔬🧑‍🔬

[Francois Lebreton @Fr_Lebreton]

Our latest paper is out in preprint! https://t.co/1Ui9F6lnz9 With routine WGS we detected an outbreak of MDR Pseudomonas with cases spanning > 10 years! Turns out contaminated sinks in ICU rooms were part of the problem. Cases are slowing down now.

[melissa j martin @luluScience]

SIX extensively drug resistant isolates recovered from an injured Ukrainian soldier including ST-395 K. pneumoniae that was non-susceptible to all antibiotics tested. Long read sequencing underway!! @Fr_Lebreton @Brendan67357746 Ting Luo Patrick McGann
https://t.co/rZssO67y8L

[melissa j martin @luluScience]

@Fr_Lebreton @wrair All isolates are FREE and can be requested from BEI Resources under catalogue #NR-55604 (https://t.co/FcBkhZ6xDM). We are having fun seeing where they go! Stay tuned for more data on this panel! @Fr_Lebreton (3/3)

[melissa j martin @luluScience]

As of May 2023, our panel of 100 diverse Klebsiella pneumoniae clinical isolates have been requested and shipped to 151 academic and industry labs in 21 countries! @Fr_Lebreton @wrair (1/3)

[melissa j martin @luluScience]

Our paper describing these isolates/genomes for the research community was recently published in Microbial Genomics: https://t.co/FldQ1zNLdL @Fr_Lebreton @wrair (2/3)

[Olaya Rendueles @OlayaRendueles]

Thrilled!
The #Klebsiella Diversity Panel ordered last weeek is already paying off .. the shipping costs!

We mined the genomes searching for a specific mutation which results in an interesting colony morphotype -similar to👇🏼👇🏼
from @schauflerlab 1/2

https://t.co/1VBlnggpM1