Lynn Yi

[Arjun Raj @arjunrajlab]

Try and find people who give you useful responses. Some always say “great!” Some always say “bad!” Seek those with dynamic range in their evaluations. Also, some people are good for brainstorming, some for evaluation—these are not the same.

[Joy Wu, MD, PhD @JoyYWu]

With our publication in @NatureMedicine on pandemic-related barriers to the success of women in research, I’d like to shine a spotlight on gender equity for women physician-scientists, who face cumulative barriers imposed in medicine AND science https://t.co/7TlbyIsHAp 1/n

[Leah Pierson @leah_pierson]

Some people (me) do an MD-PhD in part to keep our career options open. I don't think this reasoning makes much sense because:

1) Doing an MD-PhD greatly limits your options for 8 years at a time (your 20s) when many would otherwise have tons of options (e.g., because no kids).

[Pradeep Natarajan @pnatarajanmd]

I only started my lab a little over 4y ago as an Instructor @harvardmed @MGHHeartHealth with a new K08 award in hand.
4 R01 awards as PI later, here's what I've learned as a physician-scientist:

[Lynn Yi @lynn__yi]

And there is! https://t.co/VrUl7DTkCz It would be interesting to explore whether the subset of pts w/ COVID-induced psychosis also has increased inflammatory markers as a further window into the connection b/w neuroinflamm & mental illness.

[Lynn Yi @lynn__yi]

Cool work by Prof. Iwasaki showing COVID infx -> increased CNS cytokines and microglial activity, both of which have been noted in primary psychosis as well. Which begged the question as to whether there is such a thing as COVID-induced psychosis.

[Prof. Akiko Iwasaki @VirusesImmunity]

How can a mild respiratory SARS-CoV-2 infection lead to longterm neurological symptoms? Possibilities include 1) direct infection of 🧠, 2) autoimmunity, and 3) inflammatory impact of infection distal to the 🧠. In this study, we focused on 3) 👇🏽 (2/)

[Prof. Akiko Iwasaki @VirusesImmunity]

How can a mild respiratory SARS-CoV-2 infection lead to longterm neurological symptoms? Possibilities include 1) direct infection of 🧠, 2) autoimmunity, and 3) inflammatory impact of infection distal to the 🧠. In this study, we focused on 3) 👇🏽 (2/)

[Prof. Akiko Iwasaki @VirusesImmunity]

So excited to be a part of this important study led by @michelle_monje on how significant longterm neurologic damage can occur after a mild respiratory-only SARS-CoV-2 infection. My own🧵on the findings of this study with relevance to #longCovid (1/)

https://t.co/MgXZRrh899

[Lynn Yi @lynn__yi]

@MarkRMullen @adamcifu @jbcarmody @vineettiruvadi @BenMazer I see the thoughts of a fellow psychiatry resident. :)

[Talkowski Lab @TalkowskiLab]

1/12
Our latest autism genomics study is finally done 🎉🎉
Our teams aggregated lots of genetic data to explore shared and distinct genes, mutations, and cellular expression patterns across ASD, developmental delay (DD), and schizophrenia (SCZ) cohorts. https://t.co/fHDONxUYoA

[Adam Cifu @adamcifu]

Year in Review #9
The final one for the this year.
Hope everyone has a enjoyable, healthy (twitter-free?) holiday ahead.
If you enjoy these, I store most of my twitter slides here. https://t.co/8pUEKRIRwI

[Ben Ackerman, PhD @backerman150]

Happy Mask-mas to all, and to all a good vax! 💉😷🎄 #EpiTwitter

[NimwegenLab @NimwegenLab]

Did you know that, in E. coli, the structure of the gene regulatory network does not only control the average expression levels of genes, but also their noise levels, i.e. that expression noise is itself a regulated quantity? Check out our paper. 1/n https://t.co/nMxwP5SmHn

[Lynn Yi @lynn__yi]

@la_meirelles @Hypat1aYu @Caltech congrats Lucas!!

[Lior Pachter @lpachter]

Our Clytia medusa cell type atlas introducing WHAMseq is out. This collaboration, with Tara Chari, Brady Weissbourd, @JaseGehring, @AnnaFerraioli_, @Leclere_L, Sandra Chevalier, @richcopley, @Clytia_Vlfr and David Anderson now has me hooked on jellyfish! https://t.co/ENc64q9HTT

[Sofi Quinodoz @sofiquinodoz]

Introducing a dramatically improved method, RD-SPRITE, to simultaneously map RNA-RNA, RNA-DNA, and DNA-DNA organization in the cell. [1/7] https://t.co/NNSeiqyWUT

[Valerie Arboleda MD, PhD 🤷🏻‍♀️ @ArboledaVal]

Testing is key and we need more of it. Our team at @dgsomucla and @OctantBio have worked tirelessly over the past three months to develop SwabSeq: A high-throughput platform for massively scaled up SARS-CoV-2 testing https://t.co/xZ7oYSbQ6D
/1

[Lior Pachter @lpachter]

I'll be visiting @MIT tomorrow to talk in the Bioinformatics Seminar (Feb 19th. 11:30am -1:00pm in 32-G575) on work with @sinabooeshaghi @yarbsalocin @JaseGehring @s_hateley @LambdaMoses @pmelsted @vntranos @hjpimentel & @lynn__yi. Looking forward to seeing many colleagues.

[Lynn Yi @lynn__yi]

@FertigLab presents at Ucla Caltech MSTP research conference on applying matrix factorization techniques to oncological datasets to investigate molecular patterns of treatment response.

[Lynn Yi @lynn__yi]

More info here: https://t.co/VzhR5M1T4h

[Lynn Yi @lynn__yi]

@23andMeResearch is hosting the Future of Phenotyping conference. Tune in live here via zoom: https://t.co/0pOXb0AmGg #Pheno19 @23andMe