For the second time this month, a team of researchers has reported harnessing a precise gene-editing technique to alter the DNA of human embryos
https://t.co/Ma04mPTglQ
Biologic Medicine Breakthrough
"Researchers just genetically engineered a human hookworm, Ancylostoma ceylanicum, to produce and deliver a therapeutic antibody inside a living host."
"They say hookworms will be an ideal platform for long-term biologic drug delivery because they naturally survive in hosts for years while continuously secreting molecules into the body."
"Hookworms already release roughly 1,000 different molecules into their hosts. The researchers asked: What if we added one more molecule that is therapeutically useful?"
"The engineered worms produced an anti-tetrodotoxin (TTX) antibody that entered the bloodstream of infected hamsters and showed toxin-neutralizing activity."
Hookworms infect nearly 500 million people worldwide and have evolved sophisticated ways to deliver molecules into their hosts.
This study is the first demonstration that a genetically modified human hookworm can function as a living therapeutic delivery platform.
Future engineered parasites could potentially live in the gut and continuously manufacture biologic medicines for extended periods after a single administration.
And that would be game changing!
@odvraten@JazzBulgaria The problem is you want to torture the ones that say they are Bulgarians and have Bulgarian roots in Macedonia. We will not allow it and no politician will do it. We have 100% consensus.