Our new preprint demonstrates the impact of spike mutations on the activation of the fusion core in the D614G, Delta, and Omicron variants. These findings provide insights into why Omicron requires a greater quantity of ACE2 for fusion core activation than Delta. @VothGroup
Iโm excited to share our recent work on SARS-CoV-2 nucleoprotein! It investigates the specific N-protein/lipid interactions that are critical for SARS-CoV-2 assembly and budding.
@VothGroup@Stahelin_Lab
New preprint online from the Stahelin lab and collaboration with the laboratory of Gregory Voth @VothGroup lead by Mandira Dutta. Anionic lipid interactions of the SARS-CoV-2 nucleoprotein!
https://t.co/8CRMKbcH7Z
A nice distraction for election day :) Our story on SARS-CoV-2 M protein structure is out in eLife. Congrats @KimDolan_UCB @Mandira_10@kerndm + thanks to @VothGroup and @AbhayKot for a(nother) fun collaboration! https://t.co/RT0iU7w7xr
Presenting a high-resolution #cryoEM structure of the Membrane protein of #SARSCoV2, the most abundant protein in the viral envelope and a potential target for vaccines and therapeutics. Read the #ReviewedPreprint from the lab of @SteveBrohawn here: https://t.co/Xbj6iUxGSI