Mark Wong

[Mark Wong @markwongphd]

This drug class is really moving into “one to rule them all” territory 👍 https://t.co/SXa71FJqdE

[Mark Wong @markwongphd]

Great news for patients! https://t.co/FG38EGdDFH

[Nature Reviews Drug Discovery @NatRevDrugDisc]

For readers interested in next-generation GLP-1-based drugs such as Lilly's oral candidate orforglipron, here's a comprehensive review from @DanielJDrucker
https://t.co/pM3Xc3F4u0
https://t.co/X714Dj2BNb

[Michael Albert, MD @MichaelAlbertMD]

📊 New 4-Year Study: mRNA COVID Vaccines & Mortality

A 2025 JAMA Network Open study followed 28 million French adults (18–59) for almost 4 years. Key takeaway:

👉 No increased long-term mortality from mRNA COVID vaccines.

In fact, vaccinated adults had a 25% lower risk of death from any cause compared to unvaccinated adults, after adjusting for age, sex, socioeconomic status, and 41 comorbidities.

Other findings:
🔹74% lower risk of death from severe COVID-19 in vaccinated individuals.
🔹Lower mortality across major causes (cancer, cardiovascular disease, external causes).
🔹Short-term mortality was 29% lower within 6 months of vaccination.

📌 Bottom line:
Four years of national-level data show no signal of excess mortality—and suggest long-term safety of mRNA vaccines.
https://t.co/ISAXaWUD9D

[Mark Wong @markwongphd]

Interesting interim (12 wk) data from Wave. The fat loss data are impressive but there isn't a major decrease in body weight or LM increase (expected). Looking forward to the '26 updates with the 600mg dose and longer follow up to see how the data evolve
https://t.co/fnm8K5doOa

[Mark Wong @markwongphd]

Huge amounts of bird-flu virus found in raw milk of infected cows https://t.co/KIdvW4YYkf

[Mark Wong @markwongphd]

Pioneers of mRNA COVID vaccines win medicine Nobel https://t.co/zQpF42TEtx

[Mark Wong @markwongphd]

How to Make this Moment the Turning Point for Real Change by @BarackObama https://t.co/Ik4MaIAI1l

[Mark Wong @markwongphd]

@DanChenMDPhD What about CD200? An earlier paper suggested agonizing CD200 in an influenza animal model calmed macrophage overactivation

[Mark Wong @markwongphd]

Someone gave their Toronto neighbourhood an incredible live music performance during self-isolation https://t.co/rVJEtNnx88

[Andy Biotech @AndyBiotech]

#COVID19 South Korea encouraging sign continues again

-Daily new case# declines 5 days in a row
518➡️483➡️367➡️248➡️131

-Total cases: 7382➡️7513

-Deaths: 51➡️54

Many appear to take comfort in SK's trajectory. Just remember it only happened w/ broad testing + strong mitigation

[Mark Wong @markwongphd]

@marchodges Imagine being Asian and that happening as it did today... me coughing I mean, not the judging... people didn't seem to care ;-)

[Mark Wong @markwongphd]

Another HIV vaccine strategy fails in large-scale study https://t.co/Ewqjn2netf

[Andy Biotech @AndyBiotech]

This is fascinating!

Long-term in vivo microscopy of CAR T cell dynamics during eradication of CNS lymphoma in mice
https://t.co/Y8tC0cRsEU

How intracranially injected CAR T cells invaded deeply into the solid tumor, reduced tumor growth, induced regression of CNS lymphoma

[Mark Wong @markwongphd]

Singh handled this very well - kudos!

[Supriya Dwivedi @supriyadwivedi]

Oh god the video is so much worse than the written description of the interaction

[Endpoints News @endpts]

'Worse than ever,' Boston's biotechs stare down traffic crisis — prompting call for more remote working, flex hours https://t.co/V6yeabVFlR

[Lisa Jarvis @lisamjarvis]

The first wave of KRAS G12C inhibitors are in the clinic--my long read on how chemists finally cracked this tough cancer target & what that work may (or may not) teach us about drugging the other RAS mutants: https://t.co/ft08cGSBAs

[Mark Wong @markwongphd]

https://t.co/33VpIsGI4k

[Mark Wong @markwongphd]

This Treatment Can Cure Cancer. Can It Mend the Heart? https://t.co/pY58X89RAU