Matt Chitty

@augiefb alumnus | Medical Student | U.S. Army

[Dr. Alex Tatem @DrAlexTatem]

I am a doctor and this is correct.

[Matt Chitty @mattchitty33]

@0xexpt @AbudBakri going to need the validation on whether this is thymalin or thymulin

[Abud Bakri MD @AbudBakri]

Thymosin a1 is not thymalin…

Ta1 is approved in other countries as a treatment for hep b/c. Was approved in U.S. as zadaxin for kids born without a thymus in conditions like Di George.

Had sepsis trials recently here that weren’t exciting

Thymalin is a polypeptide approved drug in Russia and other USSR countries that has human trials as a infection protection agent as well as a therapeutic agent ranging from 1970s research on Soviet soldiers to hospitalized patients during the pandemic in 2021

[Abud Bakri MD @AbudBakri]

I didn’t say they’ve been around for 40. Theyve been around far longer.

I said Khavinson did human trials on his 20-30 peptides for that long

Look up the research on Khavinsons thymalin. The first trials were in the 70s and the latest were during the pandemic

[Abud Bakri MD @AbudBakri]

I don’t think you guys realize how earth shattering this concept is

the central dogma of biology is DNA -> RNA -> protein

Khavinson suggest that the body is even smarter

After proteins are broken down, they generate peptides which further regulate the genome and other proteins. Why waste a protein when we can use it again as a signal before recycling the amino acids?

Biology is beautiful

This has already been confirmed with GHK, which is a fragment of collagen and goes back and influences collagen production genes

This create a far more targeted control of the genome

[BowTied Biohacker @BowTiedUM]

"There's no peer reviewed evidence "

Translation: "I'm waiting for the people with misaligned incentives, funding, disproportionate control over flow of information, and a history of bad faith actions/incompetence to give me permission to believe this"

[CoffeeBlackMD @CoffeeBlackMD]

Why do so many combat military and police (and men formerly so) wind up on TRT?

It’s because they are knuckledraggomg meat heads who want to be lazy bullies right? Right?

Or.

Is this a cohort of men who are doing the stressful and dangerous work so you don’t have to. Maybe it’s the long shifts and combat deployments? Cranking on cortisol. Nights awake so YOU can sleep. Volunteers to stand in the gap.

Grind a man like that in that mill long enough. And he will go hypogonadal and symptomatic.

There is no cynical conspiracy to “target” these guys. It’s all realities on the ground.

Try to remember that before getting judgy. Walk a mile in those shoes in your mind.

Similar happens with firefighters, paramedics, EMTs, any physician in acute care (emergency, critical care, and surgery), and anyone doing when needed infrastructure work/repairs like linemen (night time snow storms and your electricity is out).

I’d love an easier and less stressful life. So would all these guys. But we were called. And the work has consequences.

[Noah Ryan @NoahRyanCo]

Finasteride ruins lives. There is a concerted effort to sweep post-finasteride syndrome under the rug simply because of how big of a business a hairloss drug for life is.

This drug clearly can cause an epigenetic cascade of hormonal and neurosteroid dysfunction, leading to issues like:
- Total loss of libido
- ED
- Testicular atrophy
- Brain fog
- Anhedonia
- Anxiety
- Fatigue
- Muscle weakness
- Joint pain

To dismiss this condition rather than question the safety of this drug is senseless

[Justin Mihaly @JustinMihaly]

Bodybuilders have been so far ahead on nearly every health, biohacking, cutting edge medical trend so far before anybody else knew these things existed

[Andrew D. Huberman, Ph.D. @hubermanlab]

Hands down @AbudBakri MD is the most informed human alive on the topic of clinical use of & history & data & experimentation w/peptides… (not talking insulin here but yes GLPs, BPC, GHK, Pinealon, epitalon, MT, GH secretagouges, etc). PEPTIDES MASTERCLASS:

[Andrew D. Huberman, Ph.D. @hubermanlab]

PEPTIDES MASTERCLASS. A must listen if you’re peptide curious, peptide skeptical, bullish on peptides, or anti. The science, the uses, sourcing, concerns, and much more. @AbudBakri thank you for such an informative discussion.

[Scicomm Media @scicomm]

Tomorrow's Huberman Lab episode is with Dr. @AbudBakri, MD, a physician and clinician specializing in peptide therapeutics and their applications in healing, immunity, and longevity.

Dr. Bakri and @hubermanlab discuss BPC 157, the difference between GLP-1s and the "Russian" peptide bioregulators, thymus health and immunity, and overlooked markers of longevity.

[SilverFoxLeo @BowTiedHRT]

The TRT/HRT protocols we’ve seen suggested by “TRT doctors,” PCPs, and particularly Endos would absolutely blow your mind.

No wonder so many men and women who finally manage to get on an HRT protocol through the traditional routes feel worse than they did before they got “treatment.”

[Abud Bakri MD @AbudBakri]

Traditionally trained and practicing physicians have an opportunity to rigorously approach the peptide field and make it safe and effective

Otherwise you’re going to get stooges dominating the field, people will get hurt, and the whole industry will be set back

Good studies, great patient care

The peptides are coming anyways. Might as well pioneer it

This is challenging as most physicians now are low in openness, high in neuroticism. “Follow the “guidelines”

We’re making the new guidelines

[Grey Zabel @GreyZabel]

Bad night to be a Busch Light…. #victorybeers 😎

[Andrew D. Huberman, Ph.D. @hubermanlab]

All the celebs now getting that retrutatide look. If you want to know what will be massive on legal RX market 2 years ahead in the fat loss, muscle, vitality space… it always goes from bodybuilding (GH, TRT, GLPs, Retra.) to Hollywood to mainstream. EVERY TIME. Since the 80s.

[Rep. Anna Paulina Luna @RepLuna]

There is a massive push by Pharma right now to kill peptide use and specifically go after compounding pharmacies. Based on some of the research I have seen, peptides have some pretty incredible medical properties and are doing wonders for people. At any rate, Pharma has a tendency to tip the scales on anything that could potentially cost them revenue. I want to raise this issue for everyone so that you can get involved.

[Abud Bakri MD @AbudBakri]

The worse side effect of creatine:

Medical incompetence

As thousands of people start taking more creatine, more doctors are going to start thinking people have kidney failure based on erroneous analysis of labs

Results? $$$ wasted on workups

All they had to do is ask: are you taking creatine and order a Cystatin c

[Abud Bakri MD @AbudBakri]

Guys it’s pretty simple:

🟢 If you’re on creatine AND your creatinine comes up normal, don’t worry

🔴 If you’re on creatine and your creatinine comes up elevated/abnormal, check a cyststin c.

Or even better work have that pulled at the outset, especially if you are muscular, eat a lot of protein, or take a lot of creatine

Cyststin c won’t be biased by your habits like creatinine will be

[Matt Chitty @mattchitty33]

@KatieB062500 @OutlawsPoetic @biogerontology What metrics were used to gauge kidney function in this setting? If these physicians were only testing basic panel biomarkers like serum creatinine, BUN, etc. (and not cystatin C for example), then they easily could have been confounded by the creatine supplementation.