Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer
Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived
#ASCO26
Presented at #ASCO26:
Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: https://t.co/xwLWBZYRzq
@ASCO
I am thrilled to announce that Renaissance Institute completed the initial phase of its first course of LDRT for an #Alzheimers patient today.
The patient began the treatment course with a MOCA of 15, complete anosmia & ageusia, and A&Ox1.
By the end of Renaissance-modified treatment fractionation, the patient had recovered their sense of taste, was A&Ox4, able to remember my staff’s names, and MOCA improved to 19.
We look forward to opening this new & innovative fractionation scheme in the upcoming LDRT-MIND trial.
#radonc #neurology #dementia
Imagine hearing, "You have a brain tumor." Now imagine a place where you can get the most advanced treatment and trials with whole-person support. Where a team of experts personalizes care that gives you the best chance at a better outcome. Learn more: https://t.co/2u4IsE9HfA
The UC Gardner Neuroscience Institute's Brain Tumor Center has received The Joint Commission’s Gold Seal of Approval for Brain Tumor Center Certification, making us one of just eight in the country with this recognition! Learn more about this achievement: https://t.co/3CBZlhKm9g
Congrats to @juliannakorns17@MathieuSertorio@MayaRidinger and the team on this impressive body of work: Targeting PLK1 to Enhance Radiosensitivity in HPV- Head and Neck Cancer https://t.co/5ArROE7x0u advancing treatment for our head and neck cancer patients. @uc_ccb
Pancreatic cancer moves fast, so we have to move faster. The UC Cancer Center is part of a national clinical trial testing whether high-dose targeted radiation can improve survival for patients. Learn more: https://t.co/nxSTvyKThS
NRG-GI011 (LAP100) has enrolled & randomized its 1st patient (U Cincinnati)🙏
355 to go.
The lead enroller will get dinner on me at ASCO/GI ASCO/ASTRO 😀
With @fccincinnati's victory this afternoon, Roman Celentano improved his winning percentage to 66.5% which is tied for the highest winning percentage by a goalkeeper in @MLS history in his first 100 regular season starts.
🚀 Dose escalation in LS-SCLC: A game-changer? @OncoAlert
PH II RCT evaluates BID TRT 60 Gy vs. standard 45 Gy in LS-SCLC
• 🎯 Objective: Assess if 60 Gy/40Fx BID improves OS vs. 45 Gy/30Fx BID
• 🏥 Methods:
- 170 👥randomized
- All received cis/carboplatin + etoposide
- PCI offered post-CRT
- Majority treated with 3D-CRT
• 📊 Results:
- Median OS: 60 Gy = 43.5 mo vs. 22.5 mo
- N🚫 ⬆️ in grade ≥3 esophagitis or pneumonitis
- ⬇️ intrathoracic relapses (23% vs. 37%)
- Stable long-term QoL
⚖️Conclusion: 60 Gy BID TRT ⬆️ survival without added toxicity
Future Ph III with durvalumab is planned!
#RadOnc #SCLC
Finally read SANO - Ph3 RCT showing w active surveillance, OS non-inferior & QOL better than surgery.
This is already higher level evidence than for rectal ca non-op (no RCT but now a SOC). Why such dif bars for acceptance?
IMO non-op should be option if cCR in esoph/GEJ too.
There is a promising stem cell therapy that has reduced the use of insulin by 91% and the latest clinical trial has shown even more promising data.
Read about it here!
https://t.co/TyYgkaMkhp
Congratulations to the Europa team for showing what we observe in #RadOnc clinic - a short course of RT is very well tolerated (QoL better than ET) and single modality may be appropriate for favorable risk patients. #SABC24
Today is November 7th, Marie Curie’s Birthday. Our radiation oncology team celebrates this strong, intelligent female scientist who helped change the world. In a field still dominated by men, we are proud to have 46% female faculty and 71% female residents here at UC. Here’s to the women who paved the way and those in the future that will join us to fight to cure cancer. #womenwhocurie #radonc #uchealth
The family and friends of the late Bernard S. Aron, MD, celebrated the appointment of Vinita Takiar, MD, as the first Dr. Bernard S. Aron Research Chair in Radiation Oncology.
This chair was made possible by the support of many donors.
#PhilanthropyFriday