#Myeloma Paper of the Day: African genetic similarity assoc w/ reduced inflammation/enhanced adaptive immunity, enrichment late T-effectors driven by rare cytotoxic CD4⁺s; expansion of late-differentiated adaptive NKs w/ high cytotoxic GNLY, GZMH: https://t.co/7S9VMivVFu. #mmsm
Manoj Bhasin, PhD, led the largest multi-center study on multiple myeloma published in @NatureCancer, showing that integrating immune cell signatures with known tumor cytogenetics and individual characteristics improves outcome predictions. Learn more: https://t.co/GtJO3eizXA.
#Myeloma Paper of the Day: A single-cell atlas (based on 1,397,272 cells from MMRF CoMMpass study) characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in patients with newly diagnosed multiple myeloma: https://t.co/nGcMGIMyKW. #mmsm
Proud to share our new multiple myeloma study published today in Nature Cancer! https://t.co/IXrVvBWBZ1
Analyzed >1.3 million single cells from 337 newly diagnosed patients, generating what we believe is the most comprehensive immune atlas of NDMM to date. Integrating immune states with tumor genetics markedly improves survival prediction.
This work highlights the immune system as a critical and underused dimension in understanding and managing multiple myeloma.
This work represents years of collaboration between our team at Emory University, the Multiple Myeloma Research Foundation, and four other leading academic medical centers. Thanks to everyone !!!!!
🔗 https://t.co/IXrVvBWBZ1
#MultipleMyeloma #NatureCancer #SingleCell #CancerImmunology #PrecisionOncology @EmoryUniversity@theMMRF@SagarLonialMD@WinshipAtEmory@ATLPedsHemOnc@childrensatl
Our researchers recently discovered that targeting the immune system alongside gene therapy may improve outcomes for babies with spinal muscular atrophy, a genetic disorder that weakens motor neurons. Read the study: https://t.co/zkX5CkqXMu.
Aflac researcher Manoj Bhasin, PhD, recently published in @Leukemia Journal, the first study showing mast cells shield tumor cells in pediatric AML. Their increased presence may indicate a need for more aggressive treatment. Learn more: https://t.co/NcuVXxB814.
Researchers from Winship and @childrensatl@ATLPedsHemOnc led by Manoj Bhasin, PhD, MS (@mbhasin_) have published the most comprehensive single-cell analysis of pediatric leukemia to date in @Nature Communications. 🔗 https://t.co/3Osa04i4mD
Registration is now open for the 3rd Annual Workshop on Genomics! Reserve your space to join your colleagues in Lisbon July 11-12.https://t.co/hLuF6yT4Qb
At AWSOM25, the keynote talk by Dr. Soumya Jain showcased breathtaking single-cell and spatial transcriptomic data, offering deep insights into brain development.