Margaret Helmuth

Biosatistician and Health Researcher at @MiKTMC @umichmedicine

[FDA Drug Information @FDA_Drug_Info]

For patients with the rare kidney condition FSGS without nephrotic syndrome, treatment options have been limited. A new approval offers hope. https://t.co/nU4rYdlKr5

[Shikha Wadhwani @SWadhwaniMD]

🎉🎉🎉Historic day for the #FSGS community— the FDA has fully approved Sparsentan as the first drug for patients with FSGS!! And in addition to adults, it’s approved for children ages 8 and over too 🙌

Special shout out to the #PARASOL ☂️ project that played a pivotal role in defining endpoints for FSGS trials!

So proud to be a part of this amazing community (& former investigator for the DUPLEX trial). And grateful my patients now have a therapy to treat a devastating kidney disease 🙏🏼 @ISGDtweets @nephcure @LauraMarianiMD @ASmith_Stats @mehelmuth @KretzlerM @rheault_m @kirkcampbell

https://t.co/TqsyUVXNui

[Margaret Helmuth @mehelmuth]

I am so proud of this community and proud to be a part of this historic moment ❤️

[International Society of Glomerular Disease @ISGDtweets]

More than 100 years after #FSGS was first described, we have the first FDA-approved treatment. A proud day for the collaborative #ParasolProject led by ISGD, @nephcure, @KidneyHealthIn and @nkf! This is what happens when the global community unites to transform glomerular health, and it's only the beginning. ⛱️ https://t.co/GlxbrqlzP6
@LauraMarianiMD @KretzlerM @Tobias_B_Huber @ASmith_Stats @mehelmuth @MiKTMC

[International Society of Glomerular Disease @ISGDtweets]

PARASOL biostats leads Abigail Smith and @mehelmuth gave a guest lecture in @HamiltonCollege BIO 202: Biostatistics class - Nice examples to learn about statistical methods & considerations in longitudinal studies and clinical trials & highlight real life impact of biostats work

[Margaret Helmuth @mehelmuth]

This is huge! I'm so proud to have been a part of making this happen!!!

[Dimerix @dimerixltd]

✅ Major milestone: FDA confirms proteinuria as an acceptable primary endpoint for full marketing approval of DMX-200 in the US.

A significant step forward for Dimerix and #FSGS patients.

Learn more: https://t.co/n7LwfMhKVb

[Margaret Helmuth @mehelmuth]

I'm proud to be a part of this work and team! @ASmith_Stats @LauraMarianiMD https://t.co/z9ApLcsheL

[AJKD @AJKDonline]

Association of #COVID19 vs COVID-19 Vaccination With Kidney Function and Disease Activity in Primary Glomerular Disease

https://t.co/HL2jZx6c3I (FREE temporarily)

@mehelmuth @asbomback @IqtidarMyda @KatherineTuttl8 @RBouMatarMD @Larrypedkid @brurobinson1 @rheault_m @CureGn

[International Society of Glomerular Disease @ISGDtweets]

A small subgroup of the PARASOL team celebrating with our well-traveled banner

[Margaret Helmuth @mehelmuth]

@ISGDtweets #DreamTeam @ASmith_Stats

[International Society of Glomerular Disease @ISGDtweets]

PARASOL biostats all-stars Abigail Smith and @mehelmuth with the poster! #KidneyWk

[International Society of Glomerular Disease @ISGDtweets]

A little stroll post-PARASOL workshop took us to the place where the magic happens @NIH @Moinsaleem @Tobias_B_Huber @DannyGale_1

[Daniel Gale @DannyGale_1]

The fantastic @LauraMarianiMD revealing data-derived trial endpoint proposals to allow feasible clinical trials in #FSGS #ParasolProject @ISGDtweets

[SSC_Lab 🧬 @SannaCherchiLab]

Excited to announce our recent paper "Natural History and Clinicopathological Associations of TRPC6-Associated Podocytopathy" appearing today as pre-print in @JASN_News
A great collaboration across the world to put together 64 cases for 39 families segregating TRPC6 missense variants and describe their course of disease and clinicopatological features!
#FSGS #RareDisease #HumanGenetics #TRPC6 #rFSGS #nephroticsyndrome
@GlomCon @ISGDtweets @GbadegesinLab @TheSampsonLab @actiobiosci @CUIMCGlomCenter @asbomback @Martinelli_Elen @ASNKidney @the_asci @tzeyinlim @JMartinoActual @SlavePetrovski @AstraZeneca @mehelmuth @kidneyomicsamps @KretzlerM @CureGn @Moinsaleem @nephcure @ASPNeph @NephroticSyn @NephroticF @ESPNSociety @IPNA_PedNeph @thePNRC @AmerAcadPeds @rFSGSInitiative

https://t.co/5SS25rWwko

[Michelle Rheault @rheault_m]

Increased risk of kidney failure in patients with genetic kidney disorders @CureGN https://t.co/nBVNnHcYeL

[SSC_Lab 🧬 @SannaCherchiLab]

Thank you for reporting!
More to come on this, stay tuned :)
#APOL1 #FSGS
@GbadegesinLab @kidneyomicsamps @TheSampsonLab @OpeyemiOlabisi8 @H3Africa @goKDIGO @PrAniang @CUIMCGlomCenter @ApolloNetwork13 @GuptaYask @ilori_titi @AfricanAFRAN @dhekidney @NephJC @MegSise @mehelmuth @CureGn @kirkcampbell @GlomCon @LauraMarianiMD

[Margaret Helmuth @mehelmuth]

I'm so proud to be a part of this amazing team!!!

[International Society of Glomerular Disease @ISGDtweets]

Bringing together the PARASOL team in Reykjavik with a dash of midnight sun (sunset photo from 1 am) to make progress on FSGS!

[AJKD @AJKDonline]

@AdamSWilk @RachelPatzerPhD @EmoryNephrology @EmoryRollins @CKiDStudy @ngderekk @funsocdoc @suefurth_chop @HopkinsPedsNeph @HopkinsMedicine @makimugwe @AmitXGarg @GmcnattGwen @RajSarabu @KristaLentine @scholes_nicki @talia_gutman @DominelloAmanda @JonathanCCraig @germjacq @allisonjaure @SumitMohanMD @amal_trivedi @jennyhcchen @kimberleyminas @DWJohnsonNeph @MaleekaLadhani @a_viecelli @RachaelCWalker @charmaine_lok @DMohottige @MaryniaKolak @Abelkho @NUFeinbergMed @VUMCepi @DukeKidney Racial & Ethnic Disparities in Acute Care Utilization Among Patients with Glomerular Disease

https://t.co/SowvQoafo6 (FREE temporarily)

@JKrissberg @MichelleOShaug3 @mehelmuth @SalemAlmaani @KayeBrathwaite @DoreyGlenn @CureGn

[Jon Klein PGY46 🇮🇱 @JonBKlein]

Just out. Proud to work with these folks from @UMichKidney , @UNCKidney @nationwidekids and @CureGn and @nephcure

“Elevated Exposure To Air Pollutants Accelerates Primary Glomerular Disease Progression”

https://t.co/LSP6MH7TLN

[World Congress of Nephrology @ISNWCN]

@RoRvm @deniise_am @priti899 @drpriyajohn @SabineKaram6 @nephromythri @sibgokcay @DTomacruzMD @myadla @divyaa24 @krithicism @khalida_soki @FerArceAmare @IgAN_JBarratt @dra_miliflores @BradRovin @VladoPerkovic "Predicting Patient Response to Standard-of-care Therapies in Glomerular Diseases" by @mehelmuth @LauraMarianiMD, et al, is presented at WCN'24 in Buenos Aires. Their work was transformed into a visual abstract by #ISNWCN Social Media Team member @goldenglom

[International Society of Glomerular Disease @ISGDtweets]

ISGD reunión during the WCN’24:

✅ Members from around the 🌎
✅ GN in ten
✅ Parasol project
✅ Defining MCD and idiopathic nephrotic syndrome
✅ Hot topics in GN session webinar May 10 2024

[International Society of Glomerular Disease @ISGDtweets]

😊Thank you to everyone who came to this morning's breakfast! Wonderful to meet so many members in person and especially to connect w/ the outstanding neph community here in Argentina and Latin America. We're looking forward to future collaborations! 🎉
-Laurel and Tobias