Delighted to announce that I've launched a company, Decrypt Bio! My co-founder, the rest of the team, and I are combining simulations and experiments to drug cryptic pockets.
You can learn more at our avant-garde website😀
https://t.co/mixDr9nXLU
If you cant resolve individual atoms you dont have an atomic structure 🙄 why is that so difficult to grasp? So many people just say atomic this atomic that then proceed to discuss a 4A map ... not cool
Now peer-reviewed @ImmunityCP! https://t.co/VbxwEMdAuk. Added structural studies by @menchant_liu, Wilson lab reveal recurrent S2 antibody features that could be exploited by targeted pan-betacoronavirus vaccines. Thanks again to all the wonderful collaborators on this study!
Our new study led by @WenhaoO & @timothyjtan measured the effects of thousands of NTD single mutations on S protein expression. There are two interesting findings. (1/6)
https://t.co/uMEc91xaCL
Exciting new flu work from Julianne + the Wilson lab and @florian_krammer shows that chimeric HA universal flu antigens are flexible and present a broadly protective trimer interface epitope. Read all about it - https://t.co/jNVe4YWcpI
New, really cool CIVICs study with Ian Wilson and @WardLab1 showing that our cHA constructs support binding of HA stalk AND trimer interface antibodies! @niaidcivics https://t.co/W9kUXYEyut
Below: Structure of cH15/3 with FluA-20 and stalk mAb bound!
Our new study led by @menz45 analyzes data in literature and describes the molecular features of a public antibody response to SARS-CoV-2 RBD that is encoded by IGHV2-5/IGLV2-14 and can potently neutralize all VOCs to date. (1/10)
https://t.co/sQtm7jyvPQ
AAI is pleased to welcome attendees to IMMUNOLOGY2022™! We look forward to seeing everyone who has traveled to Portland for our first in-person annual meeting since 2019, and to the exciting sessions and events planned for you! #AAI2022
In our latest pre-print (https://t.co/tmLJLVDEHW), led by Panpan Zhou & @Sophie_GeSong, we isolated a large panel of broadly neutralizing antibodies (bnAbs) from SARS-2 “recovered-vaccinated” humans that target a conserved S2 site in the fusion machinery on betacoronavirus spikes
Great collaboration with the groups of @BenjMurrell and @NillaKH on the structure of a affinity-matured public antibody bound to the Omicron spike. @DannySheward@Pradee05 @das_hrishikesh1 https://t.co/cL8t78fPRx