Meshal K. Alghanem

Lecturer @KFUniversity | BSc in Pharm.D @_KSU | MSc in Cancer Sciences @RoswellPark | Ongoing DPhil in Clinical medicine / Pharmacology @UniofOxford

[Meshal K. Alghanem @meshalkalg]

"EASE IS A GREATER THREAT TO PROGRESS THAN HARDSHIP"
-Denzel Washington-

[Denis Wirtz @deniswirtz]

Precancers in the human pancreas.

Imaged in 3D here using CODA.

More here: https://t.co/RsB0RYohT0

About CODA: https://t.co/OrRXmybBZe

[Nature Chemical Biology @nchembio]

De novo design of potent CRISPR-Cas13 inhibitors provides a strategy to rapidly design off-switches for RNA-editing systems

https://t.co/cJu0mirpbw

[واس الأخبار الملكية @spagov]

سمو #ولي_العهد يستقبل البروفيسور عمر بن مونس ياغي بمناسبة فوزه بجائزة نوبل في الكيمياء لعام 2025، مقدمًا له التهنئة على نيله الجائزة التي تعكس تقديرًا وتكريمًا لجهوده وما يقدمه في مجال الكيمياء، متمنيًا له دوام التوفيق.
#واس

[ILLIASUL IBAD @IlliasulK]

GLP-1 drugs and cancer?

A new study shows colon cancer patients on GLP-1s had a 5-yr mortality of 15.5% vs 37.1% in non-users.
That’s MASSIVE.

Researchers say it may go beyond weight loss — GLP-1s may be reshaping inflammation, immunity, metabolism, even tumor biology.

From diabetes → obesity → heart → kidney → now possible anticancer effects.

We’re watching the start of something BIG. 🔥

#GLP1 #CancerResearch #ColonCancer #MedTwitter #RheumTwitter #Oncology #ObesityMedicine #Metabolism #Healthcare #MedicalNews #Ozempic #Wegovy @DrAkhilX @IhabFathiSulima @CelestinoGutirr @Urchilla01

[Nirosha J. Murugan @niroshajmurugan]

Your cells (and not just the ones in your brain) remember.

Fat cells retain an “obesogenic memory” after weight loss: an energetic imprint that primes them to store again.

Viewed through the Energy Resistance Principle (ERP), this is a regulatory strategy for energy efficiency.

Rather than burning energy to reprogram tissues after each feast or famine (a costly, entropy-generating process that amplifies éR) the body encodes past flux into stable epigenetic states. This avoids unnecessary resistance, minimizes entropic waste, and optimizes energy flow.

This is LTP for fat cells: a form of long-term potentiation outside the brain. A kind of somatic “energetic” memory that spares the system from future resistance overload.

What other tissues might hold similar efficiency-promoting memories? What flux imprints are shaping your physiology right now?

🔗: https://t.co/HRQxrBkVfo

[Nature Reviews Drug Discovery @NatRevDrugDisc]

For readers interested in next-generation GLP-1-based drugs such as Lilly's oral candidate orforglipron, here's a comprehensive review from @DanielJDrucker
https://t.co/pM3Xc3F4u0
https://t.co/X714Dj2BNb

[Cancer Cell @Cancer_Cell]

CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases https://t.co/OMVujtbvQ1

[Waggoner Lab @LabWaggoner]

Preview @ImmunityCP
Burning the candle at both ends: ROS-mediated telomere damage drives T cell dysfunction
https://t.co/s6pl5w2t4j
on
https://t.co/uIptYSN3u4

[Pierce @PierceOgdenJ]

Excited to announce mBER, our fully open AI tool for de novo design of epitope-specific antibodies. To validate, we ran the largest de novo antibody experiment to date: >1M designs tested against 145 targets, measuring >100M interactions. We found specific binders for nearly half the targets, with up to 40% hit rates. Thread below:

[Meshal K. Alghanem @meshalkalg]

الحمد لله دائما وابدًا 🙏🏻

[Meshal K. Alghanem @meshalkalg]

عيدكم مبارك، تقبل الله منا ومنكم صالح الاعمال وجعلنا الله من المقبولين.

كل عام وأنتم بخير 🌹

[Meshal K. Alghanem @meshalkalg]

اللَّهُمَّ إِنَّكَ عُفُوٌّ كَرِيْمٌ تُحِبُّ الْعَفْوَ فَاعْفُ عَنِّا ..

[Meshal K. Alghanem @meshalkalg]

@HUSSAM3idM الف مبروك قبولك يا اخوي حسام ، كل التوفيق ان شاء الله. 🌹

[وهج الفؤاد @arwicl]

"الذي إذا دُعي به أجاب"

[Meshal K. Alghanem @meshalkalg]

كل عام وانتم بخير

عيدكم مبارك .. 🌹

[عبدالله العصيمي | OSM @iAOsaimi]

واحدة من أجمل الفيديوهات اللي تابعتها
وانجذبت لها من أول دقيقة إلى آخر دقيقة !
من سحر الأسلوب وعذوبة السرد ما شاء الله ❤️

[Meshal K. Alghanem @meshalkalg]

مبارك عليكم الشهر ، وتقبل الله صيامكم وقيامكم. واعانا وإياكم في صيامه وقيامه 🌹

[Trends in Immunology @TrendsImmuno]

The tumor niche can reprogram long-lived protumorigenic neutrophils https://t.co/8zsG7rc8GL #immunology

[عمادة شؤون الطلاب @KFU_st_affairs]

#تهنئة لسعادة د. منصور العتيبي بمناسبة صدور قرار معالي رئيس #جامعة_الملك_فيصل بتعيينه وكيلاً للأنشطة والبرامج الطلابية، داعين الله له بالتوفيق والسداد.

#مجتمع_كفو
#عمادة_شؤون_الطلاب