In January 2022 I started doing Mass Spectrometry in Carol Robinsons lab. To start off a new video series with @Jussi02841019 about research in the @KavliOxford Institute, here's some of what I've learned so far, and what I'm hoping to do with it!
🚨 PhD Positions Available! 🚨 Join our lab at UTSA (https://t.co/kI7KzvgYy7) to study ion channel function, assembly, & trafficking using molecular biology, electrophysiology, and cryo-EM. 🧬🔬 Diverse, supportive environment in a top-tier research institution! #PhD@UTSA
🚨 Reminder: The virtual Ion Channel Symposium 2.0 is happening next week! We have a fantastic lineup of speakers ready to share the latest discoveries in the field. Don’t miss out—sign up and join us for free! ✨
https://t.co/SDDBvG3VCx
@sm_usher @HomannPoulsen@ChowHanChua
Happy to share our paper in @NatureSMB, led by @uriellopezs and Lachlan Munro. We are studying how the antidepressant vortioxetine acts on serotonin 5-HT3 receptors in rodents and humans.
https://t.co/msmgml3X2T
Congratulations to Anna Annanchenko and @RuiyanGao for their @CommsBio paper: State-dependent binding of cholesterol and an anionic lipid to the muscle-type Torpedo nicotinic acetylcholine receptor (https://t.co/d9vjtWxjsS).
On this International Women's Day, we're thrilled to spotlight @kalinanaidoo's research on #ParkinsonsDisease! Let's celebrate the achievements of women in science and beyond, and keep uplifting their voices. #IWD2023#WomenInScience#SeeTheUnseen https://t.co/nj16oN3ZNg
We have an exciting PhD opportunity in a prestigious EU-funded Doctoral Network, RepState (https://t.co/TPVKTJkXBA; #7) and accept applications through https://t.co/AddaxHOCDp.
This post (at Uni Leeds/UK) is fully funded and open to intl students.
I'm at #ASMS2023 today, with a poster on my first mass spectrometry work in the @cvr_research group, exploring how we can probe ion channel function and modulation using MS (and some 🐟🐟). I'm joined by some excellent colleagues in the 580s - do swing by!
Had a great time, and learned about lots of great science and scientists, including the impressively monikered "Shark Lady", Eugenie Clark! #WomenInScience#SharksinScience
Excited to be heading to San Diego for #bps2023! Come check out my poster (Monday Feb 20, 1:45pm) in the "Ligand-Gated Channels I" section.
B326 - RECONSTRUCTING IDENTICAL AGONIST SITES IN THE MUSCLE-TYPE NICOTINIC ACETYLCHOLINE RECEPTOR
(1/3)
Ho, ho, ho! Happy to share our new research findings showing that P2Y6 receptor‐dependent microglial phagocytosis of synapses mediates synaptic and memory loss in aging.
A special one for me, as this is my first research article as corresponding author!
https://t.co/bBlWpdnNhr
New Episode of See the Unseen is now available! Ready to hear @Jussi02841019 discussing the brain organoids with @MesoyS? We also shared some clues about the upcoming episode. Stay tuned! @NDCNOxford@OxfordMedSci@UniofOxford@OxfordChemistry
https://t.co/yrDpGDXazj
Great and thorough comparison of context effects! (Including lots of intriguing M4 changes to mull over...🤩) Look forward to pore-ing over these structures 😁
New preprint from our lab! Does the choice of nanodisc scaffold matter for single particle cryo-EM? The answer is yes (!) for the pentameric ligand-gated ion channel, ELIC. @VikramDalal_37 @PageAnesthesia @GraceBrannigan@wuccilab@WashUanesthesia
Our latest study is now published!
"Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation" https://t.co/hZW8UxdnXE