MetAGE - Cluster of Excellence

🔬 Interdisciplinary research network exploring the metabolic control of ageing and age-related diseases. From basic science to clinical solutions.

[MetAGE - Cluster of Excellence @metage_coe]

Fasting: tradition, discipline, lifestyle.

Science adds another layer:
How does it affect metabolism, autophagy, and healthy aging? And does it make sense to add controlled fasting periods to your personal routine?
#MetAGE #HealthyAging #longevity

https://t.co/uWHIYsKo0W

[MetAGE - Cluster of Excellence @metage_coe]

Scientific excellence depends on diversity of perspectives, experiences, and voices!

On the International Day of Girls and Women in Science, we recognize the researchers shaping the future of #HealthyAging.

#WomenInScience #GirlsInScience #MetAGE

[MetAGE - Cluster of Excellence @metage_coe]

Excellent research requires excellent teams! We are happy to have such a team!

At MetAGE, we explore how interconnected metabolic processes shape health over time and how we can support healthy aging, together.

#MetAGE #HealthyAging #Metabolism #Longevity

[MetAGE - Cluster of Excellence @metage_coe]

New review from our team — @SubhashKhatri17 @Mah_abdellatif and @simon_sedej
For longevity science, this is a must-read.
👇A deep dive into NAD⁺ precursors, the clinical data behind it & how close we are to slowing human aging
#metage #Longevity #healthyaging

[Geromedicine @geromedicine]

📢Review-“Clinical evidence for the use of NAD+ precursors to slow aging”— explores current human trials on NAD precursors, highlighting promise, limits, and their potential to improve healthspan.

🔗https://t.co/l8tjHBS51U

#HealthyLongevity #aging #geroscience

[MetAGE - Cluster of Excellence @metage_coe]

🔬 Meet Dr. Brigitte Pertschy – Key Researcher @UniGraz & Head of our Training Unit
She studies how ribosomes are built & how this process changes as we age.

💡 Recently awarded a €10M @ERC_Research Synergy Grant for the project 'snoOPERA'! Congrats!
#HealthyAging #Ribosomes

[MetAGE - Cluster of Excellence @metage_coe]

Link to the publication: https://t.co/csgPzgyBFt

[MetAGE - Cluster of Excellence @metage_coe]

Tobias Madl & coworkers show how FOXO4 keeps scenecent “zombie cells” alive by binding to a disorderd region of p53. Blocking this with FOXO4-DRI initiates killing of aging cells - a potential key to anti-aging therapies.
@MedUniGraz #senolytictherapies #healthyaging #metage

[MetAGE - Cluster of Excellence @metage_coe]

Follow her research @MartinaS_lab

One recent publication: https://t.co/e6Oy3vDndF

[MetAGE - Cluster of Excellence @metage_coe]

👩‍🔬Meet our team: Dr. Martina Schweiger from
@UniGraz studies how fat and metabolism shape health, aging & disease - from obesity to cachexia.

Because having too much or too little fat affects us profoundly!

#MetAGE #HealthyAging #Metabolism #adiposetissue

[MetAGE - Cluster of Excellence @metage_coe]

Good commnication is what truly matters - no matter if young or old, in our body or beyond.

What's your take on this?

#sciencecommunication #Longevity #agingfinelikewine #MetAGE #agingresearch #metabolicsignaling #communication

[MetAGE - Cluster of Excellence @metage_coe]

Meet Dr. Thomas Scherer – MetAGE Deputy Director of Research @MedUni_Wien

As a clinician, he's not only interested in the mechanisms of age-related diseases, but also to integrate clinical intervention studies into his research.

More👉https://t.co/0NgGtccr7C #AgingResearch

[MetAGE - Cluster of Excellence @metage_coe]

Ever feel like your energy just doesn’t bounce back like it used to?
It’s not just age. It's your cells losing their metabolic flexibility.

Good news: we’re learning how to reverse it.

🔁 Join the conversation on healthy aging!
🧠 #AgingResearch #Metabolism #MetAGE

[MetAGE - Cluster of Excellence @metage_coe]

🫀Obesity speeds up aging of the heart & vessels – through inflammation, cell stress, & mitochondrial dysfunction: MetAGE researchers @Mah_abdellatif & Frank Madeo have compiled current research.
🔗 https://t.co/JdwX0x4ljC
#MetAGE #HeartHealth #Obesity #AgingResearch #LONGEVITY

[MetAGE - Cluster of Excellence @metage_coe]

Grateful for the insights&exchanges - and excited to keep building connections that support healthy aging across generations. Want to discuss some points? Enter the conversation👇🔗 https://t.co/o4iwEz0Liw #HealthyAging #MetAGE #LifelongLearning #Innovation #AgingWell #longevity

[MetAGE - Cluster of Excellence @metage_coe]

🧠 We recently attended SENovation Styria, hosted by
@medunigraz
– an event on innovation for healthier aging with voices from science, business & healthcare.

[MetAGE - Cluster of Excellence @metage_coe]

✨ Some Takeaways:
🔹 When is “old” old? → mindset vs. reality
🔹 Don't just innovate for, but with older generation 🔹 Interdisciplinary collaboration is key
🔹 Innovation thrives when young & old work together 🔹 Lifelong learning will be essential in an ageing society

[MetAGE - Cluster of Excellence @metage_coe]

🎥 How does fat metabolism shape how we age? ORF featured 'MetAGE' in a short TV clip on our research about aging and metabolism in cell models and patients.
@UniGraz
@MedUniGraz
📺 Watch here (in German): https://t.co/wr1N5BG8Qe
#healthyaging #longevity #metage

[MetAGE - Cluster of Excellence @metage_coe]

👋 Meet Dr. Mahmoud Abdellatif @Mah_abdellatif – MetAGE key researcher @MedUniGraz
He studies how aging affects the heart and vessels at the cellular&molecular levels – and how we could slow it down.
https://t.co/0NgGtccr7C #HealthyAging #HeartHealth #AgingResearch

[MetAGE - Cluster of Excellence @metage_coe]

🫀New publication from our cluster researchers: Blocking fat breakdown - not just eating less - may better treat #obesity-related heart failure (#HFpEF). Fat tissue might hold the key.👇
@simon_sedej @Mah_abdellatif @AndreasZirlik
@UniGraz @MedUniGraz @tugraz
#MetAGE

[Circulation Research @CircRes]

@CircRes Compendium on Interorgan Crosstalk in #HeartFailure and #Cardiometabolic Diseases
@Instckner et al Research Letter "Inhibition of #Adipose Tissue #Lipolysis Treats #Obesity-Related #HFpEF" https://t.co/M7d8YxkUMQ
@simon_sedej @AndreasZirlik @mah_abdellatif

[MetAGE - Cluster of Excellence @metage_coe]

Not the only, but one reason, why our research is so important 👇

#healthyaging #longevity #metage #metabolicflexibility

[Visual Capitalist @VisualCap]

The World’s Aging Population and Falling Growth Rate (1980–2100) 📉

https://t.co/2Hi5eMOhEH