🚨Simply Oncology Podcast on the ADePT trial in GBM- Dual Payload Gene Therapy🚨
1st human enrolled!
👏The science & pre human work are incredible.
🎙️ Dr Faye Robertson Edinburgh Cancer Centre talks us through the Trojan Horse that is TGX-007.
Enjoy!
@BrainTumourOrg@OncoAlert
RASolute 302 : Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer
https://t.co/o2BtMfTRph
In this phase 3 trial of 500 patients with previously treated metastatic pancreatic ductal adenocarcinoma, the oral RAS(ON) inhibitor daraxonrasib significantly improved outcomes versus investigator’s-choice chemotherapy🧪 . Median overall survival doubled (13.2 vs. 6.6–6.7 months), while progression-free survival also improved 📈 substantially (7.2–7.3 vs. 3.5–3.6 months). Benefits were consistent across populations, including RAS G12-mutant disease. Daraxonrasib demonstrated a manageable safety profile, with fewer treatment discontinuations than chemotherapy. #PancreaticCancer
@EileenMOReilly@WainbergZev@DrHendifar@MiteshBorad@FilippoPietran4@DrShubhamPant@ChiaraCrem1@DrGManji@md_oberstein@GarridoLagunaMD@pashtoonkasi@CathyEngMD@marklewismd@manjuggm@ARosen380@KoheiShitara@GillSharlene@BenWestphalen@graokane
🎙️A real treat episode of Simply Oncology Podcast in front of an audience with these amazing people
🎙️Lifestyle 🥙, Patient Voice🗣️ & Exercise 🏃♂️in #ProstateCancer with the amazing Tony Collier, @lucygoss & @AlisonBirtle ⭐️
Coming soon 🎯
@PCR_News@OncoAlert@ethansgrumps
🔬 PEACE 2 phase III: Adding pelvic RT to prostate RT + 3y ADT in very high-risk localized prostate cancer did NOT improve bPFS, MFS, CSS or OS. Borderline cPFS signal (HR 0.81, p=0.09). No added AEs. @PBlanchard_MD #ESTRO2026. @VedangMurthy what now?
we talk to Annie Anderson on advanced kidney cancer and its treatment.
Annie was diagnosed with stage IV Kidney Cancer in 2022.
She describes how continuing the things that give her joy have allowed her retain her sense of self along the way #inspired
After radical cystectomy, pelvic recurrence is devastating and we've had almost no tools to predict who's at risk before it happens.
This Mayo/Milan 5-factor model changes that.
➡️ Derived from 1,200 cases. Externally validated.
➡️ Gives us a framework to identify adjuvant RT candidates upfront not reactively (T stage, node+, margin+, <20 LNs removed)
We ask patients to accept big surgery and maybe this score can tell us who needs more. Hope the numbers at risk continue to decrease in the era of EV+P. 💡
#BladderCancer #GUOncology
🎉100 episodes of Simply Oncology Podcast🎉
🎙️27000 + downloads
🌍119 countries all across the globe.
🏘️1600 towns and cities
⭐️59 Amazing guests
Thank you to all our guests and listeners😍
Also a big thank you to people and teams supporting us along the way!!
Great news. Ph3 RASolute-302 RCT #daraxonrasib in pts with prev treated metastatic #pancreatic#PDAC demonstrated a mOS of 13.2 vs 6.7 mo for chemo (HR 0.40 (p < 0.0001). RCT in the 1L coming soon (2026).
https://t.co/4rD0wjXMcK
🚨New Simply Oncology podcast on the A to Z of Oncology🚨
🎙️Are you a patient or care who is newly diagnosed with cancer.
🎙️Are you new to working around cancer care.
🎙️Are you in training and want to learn more.
Feel free to send in your own A-Z 👍
@OncoAlert@BAUNnurses
Can ¹⁷⁷Lu-PSMA-617 fill that gap in oligometastatic HSPC?
🔹mPFS 25 vs 5 months. 52% PSA90.
🔹PEACE-1, ARASENS intensified ADT, BULLSEYE tried to defer it. Different question. Different patient.
🔹Is there room for theranostics before hormones? Maybe yes, in PSMA-avid, oligometastatic patients not ready for ADT. 🔹Phase 3 will tell. Real comparator might be MDT/SBRT. @TheLancetOncol@APCCC_Lugano@OncoAlert
🚨 New Simply oncology Podcast on Artificial intelligence in Radiotherapy 🚨
AI is the new answer to all things 🧐
🏹 We discuss the international ARCHERY trial using an AI radiotherapy planning tool to streamline RT planning with Prof Ajay Aggarwal🎯
@OncoAlert@ICR_London
🎙️Simply Oncology Podcast on PSMA Lutetium in #ProstateCancer out today with the superb Dr Amy Eccles
🎙️ Prostate Cancer Awareness Month we discuss➡️ future of PSMA lutetium & other molecular radiotherapy targets in PCa
🎙️Part 2 of 2
@OncJournal@OncoAlert@BNMSnews@UrowebESU