Mikhail Shapiro (same on bsky)

Bio-Acousto-Magneto-Neuro-Chemical Engineer
Max Delbrück Professor @Caltech
Investigator @HHMI_science
Co-founder @Merge Labs
Opinions are my own.

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

Congrats to Dr. @ishaanjdev on a spectacular defense of his PhD in Chemical Engineering @Caltech! 👨‍🎓 Ishaan developed widely useful synbio and ML tools inspired by the challenge of efficiently expressing #gasvesicles in vivo. 🍾

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

What's even better than publishing a paper with "Takoyaki" in the title? 🥟 Celebrating w. a takoyaki party 😋. Congrats to lead author (and head chef) Sunho Lee et al. Takoyaki ultrasound enables real time 3D imaging of cells and molecules.
https://t.co/66yJCAGVcZ

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

Can engineered ROS chemistry do more than label proteins or kill cells (both of which are already awesome)? 🧬 Yes! It's a versatile mechanism to control protein function. Congrats to @lhy010321, @di_wu_ and colleagues on showing how this can be done!
https://t.co/wsOeVa8Dc7

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

Congrats to Dr. @JeeWonYang_ on defending her PhD in Chemical Engineering @Caltech! 🧑‍🎓🥂 Jee Won's thesis broke ground on 3 new acoustic biosensors of enzyme activity based on #gasvesicles.

[Jacques Carolan @JacquesCarolan]

🧠 New neurotech programme alert 🧠
On 24 February @ARIA_Research is launching our newest £50m neuro programme:
Massively Scalable Neurotechnologies...

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

7/ Sorry to use the word "excited" so many times in this thread. 😆

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

Excited to co-found @Merge Labs!
TLDR: We’re developing a new paradigm for BCI using molecules instead of electrodes. If you’re excited about this and want to contribute in protein engineering, synbio, delivery, immunology, ultrasound, devices, neuroscience, or data/ML/AI, we’d love to hear from you.
https://t.co/YbMqQwePWv
https://t.co/XEG7p4NOCI
🧵

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

6/ @Merge Labs’ most important task right now is to build our team. If you’re excited about our vision and have exceptional energy, talent and skills to contribute, get in touch! https://t.co/7O1rVdFGCE

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

Thanks to all who joined the fun times at the Shapiro Lab holiday party!

[Doris Tsao @doristsao]

We’re looking for a COO for Astera Neuro! This is an all-hands-on-deck effort as we build a new paradigm for systems neuroscience, and the COO role is going to be critical. You’re: unconventional, wildly driven, 1000% mission-aligned, love management and organizational challenges, and care deeply about neuroscience/neurotech/AI/consciousness.

Age and pedigree do not matter. This should be your dream job.

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

Thanks to everyone who joined us for #ISBUS2025 at @Caltech! The future of biomolecular ultrasound and sonogenetics is blazing bright.

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

And thanks to the students for lunch and tour!

[Mikhail Shapiro (same on bsky) @mikhailshapiro]

Thanks @yaojj02 and colleagues for hosting a fun visit to @DukeUBME! Awesome time with Junjie, @GerechtSharon, @SongLabDuke, @HosseinSalahsho, @chorye, @ZhiyangJin, Phil Romero et al.