Beyond thrilled that the first paper from our lab is out today in @nature! We show that SWI/SNF loss results in gain-of-function for CTCF and cohesin, reshaping the 3D genome, and an unexpected switch between chromatin remodeling complexes.
https://t.co/RkCBfsbS3W
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The abstract deadline is approaching. This is set to be a great conference with an excellent speaker line-up and formatted to support debate and interaction. Come and join us in Philly. #lmsm@LabMelnick@ChrisRFlowersMD@frbertoni
How do BAF (SWI/SNF) mutations drive lymphoma? Back-to-back papers from our group @MDAndersonNews and @LabMelnick lab on SMARCA4 and ARID1A mutations online in @Cancer_Cell today. A brief summary...
https://t.co/eI3MHpmowe
A super elegant story from @edeon at @LabMelnick is out in @Cancer_Cell! You don’t want to miss this if you’re a fan of epigenetic, memory B cell, lymphoma or targeted therapy! Congrats to all the authors🎉
Very excited to share our new paper on how mutations in SWI/SNF chromatin remodeling complexes alter chromatin dynamics and immune cell-fate to drive lymphoma, online now in @Cancer_Cell.
https://t.co/jE1QzkSVXh
More details in the thread below.👇 🧵 1/n
So excited that our BCL10 story was finally out in @CD_AACR! It was such a great time to collaborate with @LironDavid2 and @WuLabHarvard. Also thank everyone in @LabMelnick for your tremendous help and support!!!