Darko Barisic

Assistant Professor of Cancer Biology @WeillCornell Chromatin & Epigenetics in Cancer.

[Darko Barisic @LabBarisic]

Beyond thrilled that the first paper from our lab is out today in @nature! We show that SWI/SNF loss results in gain-of-function for CTCF and cohesin, reshaping the 3D genome, and an unexpected switch between chromatin remodeling complexes.

https://t.co/RkCBfsbS3W

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[Darko Barisic @LabBarisic]

@jchellmuth @Nature Thank you Johannes! 🙏 ❤️

[Darko Barisic @LabBarisic]

Beyond thrilled that the first paper from our lab is out today in @nature! We show that SWI/SNF loss results in gain-of-function for CTCF and cohesin, reshaping the 3D genome, and an unexpected switch between chromatin remodeling complexes.

https://t.co/RkCBfsbS3W

1/n

[Darko Barisic @LabBarisic]

@JoePelt @NatureBiotech @karbalayghareh Thank you @JoePelt ! 🙏

[Darko Barisic @LabBarisic]

Excited to share our other recent paper in @NatureBiotech from Christina Leslie and our lab. We developed and in vivo validated DynaVelo, a deep learning tool that predicts rescue of genetic loss-of-function mutations. Brilliantly led by @karbalayghareh https://t.co/SW1Bv1It1w

[Darko Barisic @LabBarisic]

@FaltasLab @LabMelnick @NatureBiotech @karbalayghareh Thank you @FaltasLab ! It’s been crazy couple of weeks. 😄

[Darko Barisic @LabBarisic]

@FilipGarbicz 🙏 ❤️

[Darko Barisic @LabBarisic]

Many thanks to @WeillCornell for highlighting our recent work and for the shoutout.

https://t.co/veWecS16Yr

[Darko Barisic @LabBarisic]

@chlazaris @bloodgenes @Nature Thank you!

[Darko Barisic @LabBarisic]

@PhDShaiOvadia @jane_skok @Nature Oh that’s awesome! Thanks so much.

[Darko Barisic @LabBarisic]

@FaltasLab @landau_lab @Nature Thanks so much @FaltasLab ! 🙏

[Darko Barisic @LabBarisic]

@JoePelt @RockefellerUniv @MSKCancerCenter @WeillCornell @mason_lab @efapostolou29 Thanks Joe! Excited to see your paper soon! ❤️

[Darko Barisic @LabBarisic]

@efapostolou29 Thank you so much @efapostolou29 for all your help and your lab’s efforts to help us with this project. Truly a collaborative effort! Hope for many more collabs to come! ❤️

[nature @Nature]

Nature research paper: SWI/SNF complexes shape 3D chromatin architecture through CTCF and cohesin

https://t.co/0VxFvaEwl2

[Darko Barisic @LabBarisic]

@LScourzic Thank you, @LScourzic! ❤️

[Darko Barisic @LabBarisic]

@mason_lab @RockefellerUniv @MSKCancerCenter @WeillCornell @efapostolou29 We couldn't have done it without you, @mason_lab !

[Darko Barisic @LabBarisic]

Also big thank you to the very supportive environment at @WeillCornell @WCMLymphoma @WCM_MeyerCancer @WCMDeptofMed. Thank you to our funding sources @NIH @BloodCancerUtd @LeukemiaRF @BePositiveFdn
This was a truly collaborative effort.

[Darko Barisic @LabBarisic]

Huge thanks to collaborators at @RockefellerUniv V. Risca, at @MSKCancerCenter K. Elenitoba-Johnson, and at @WeillCornell @mason_lab, @efapostolou29 and M. Stadtfeld. & to A. Melnick, my scientific mentor for continued guidance and tremendous support.