Bratislav Misic

@TheNeuro_MNI @McgillU

[Bratislav Misic @misicbata]

Towards a biologically annotated brain connectome | https://t.co/aH0dSBtKAL

How do we integrate local biological annotations with connectome wiring?

@VinceBazz + @JustineYHansen lay out how to build and analyze annotated connectomes @NatRevNeurosci ⤵️

[Alessandro Gozzi @Gozzi_Ale]

Our latest work is now out in @NatureNeuro 🎉

Using brain scans in 🐭mice and humans 👨 we show that variable patterns of brain activity in #autism reflect distinct underlying biological mechanisms!

👉https://t.co/I8SQnOn2kI

[Kayson Fakhar @Kaysonfakhar]

🔥Our opinion piece with @DuncanAstle on “why we might be better off accepting and embracing the fact that the brain’s connectivity profile is in no way optimal” is now out on @TrendsCognSci. There, we discuss implications for Neuro-AI and psychopathology.
https://t.co/ysXhg7gT2A

[Thomas Yeo @bttyeo]

In a meta-analysis of 210 biomedical AI studies that statistically compared models under cross-validation, 97% used invalid statistical tests.

Here's our new preprint https://t.co/OG58Vkeu49 led by @tianchuzeng @kkli20111 @ZShaoshi @ten_photos 1/N

[Andrew Zalesky @AndrewZalesky]

MULTIORGAN networks across the human body over the course of aging & disease

A rapidly developing field shaped by @yetianmed & @JunhaoWen

Check out our Perspective in @NatureAging
https://t.co/mpoOQVaQhX

Concepts, priorities & recommendations to get started in the field

[Andrew Zalesky @AndrewZalesky]

Disease biology is heterogeneous, but most research reduces it to group means

NEW WORK characterizing HETEROGENEITY in BRAIN and BIOCHEMICAL biomarkers across >1/2 million people & >30 disorders:
https://t.co/lNfZH48hTJ

Check out the online resource:
https://t.co/azWezh0mAe

[Juergen Dukart @DukartJuergen]

🔬 New preprint: We introduce NEOFC—a framework linking brain connectivity to neurotransmitter systems. Reveals robust neurochemical signatures, strong noradrenergic effects, and sensitivity to drugs & psychosis.

📄 https://t.co/zRZTmHtPkJ

#Neuroscience #Neuroimaging

[Andrew Zalesky @AndrewZalesky]

Polysynaptic routes in the WHITE MATTER CONNECTOME reveal neuroanatomical basis for TMS therapy

Shorter anatomical routes between stimulation site & deep brain target predict superior response

A step fwd for Network Neuroscience!

Out now: @NatureNeuro
https://t.co/iAhLrkuJAA

[Jake Vogel @_JakeVogel_]

The lab's first published paper is here and I could not be more excited!! If you're interested in proteomics, AI or both, it could be an interesting read. Congrats @anlijuncn for a great piece of work, and big shout out to our collaborators at @_neuroproteome and @biofinder_study

[Micah G. Allen @micahgallen]

Neuropeptides act as diverse signaling molecules that regulate both basic bodily functions and complex cognitive processes within the human brain.
https://t.co/P6vkd3V30b

[Andrew Zalesky @AndrewZalesky]

Mapping connectomes in disease?

Check out our article on clinical connectomics in @NeuroCellPress

- Tractography behavior in disease
- How to measure connectivity
- How pathology impacts each stage of connectome mapping
- Multiscale connectomics
https://t.co/u4CcFuPjPL

[Eric Ceballos @ericg_ceballos]

Curious about how brain and body communicate, or how circuit states are regulated over seconds to hours? Read our paper about neuropeptide systems and how they contribute to neural architecture and function

#neuroscience

[Eric Ceballos @ericg_ceballos]

Curious about how brain and body communicate, or how circuit states are regulated over seconds to hours? Read our paper about neuropeptide systems and how they contribute to neural architecture and function

#neuroscience

[Bratislav Misic @misicbata]

9⃣ Collectively, these results show that the neuropeptide receptors are highly organized across the human brain and closely intertwined with multiple features of brain structure and function.

paper: https://t.co/ZXfy1L2VvA

data + code: https://t.co/igIP3f1KBP

[Bratislav Misic @misicbata]

Organization of neuropeptide systems in the human brain | https://t.co/v4JigZkMP4

Neuropeptides are functionally diverse signaling molecules in the brain and body.

@ericg_ceballos curates an atlas of neuropeptide receptors and relates it to brain function @NatureNeuro 🧩 🧠 ⤵️

[Bratislav Misic @misicbata]

8⃣ Finally, we replicate all findings using alternative processing and analytical choices.

We also conduct multiple sanity check/domain knowledge experiments, including detailed analysis of peptides related to feeding, sexual dimorphism and vasomodulation.