Jingdian Zhang

[Jingdian Zhang @mitoIm50243243]

With supportive experimental data from several immunology research approaches, in vivo vaccination, and in vitro polyclonal activation of T and B cells via antigen receptor stimulation, etc. Please stay tuned for another one.

[Dylan Ryan @RyanLab_TCD]

📢Preprint alert! Very excited to share the first preprint from the lab spearheaded by stellar postdoc @EloiseMLMrqs. An inherited mtDNA mutation remodels inflammatory cytokine responses in macrophages and in vivo. 1/n
https://t.co/vpqgzDsMCm

[Division of Molecular Metabolism, KI @MolMet_KI]

Join us 19th-23rd of May 2024 for an exciting #EMBO Workshop in Jozefów, Poland:

𝐌𝐨𝐥𝐞𝐜𝐮𝐥𝐚𝐫 𝐁𝐢𝐨𝐥𝐨𝐠𝐲 𝐨𝐟 𝐌𝐢𝐭𝐨𝐜𝐡𝐨𝐧𝐝𝐫𝐢𝐚𝐥 𝐆𝐞𝐧𝐞 𝐌𝐚𝐢𝐧𝐭𝐞𝐧𝐚𝐧𝐜𝐞 𝐚𝐧𝐝 𝐄𝐱𝐩𝐫𝐞𝐬𝐬𝐢𝐨𝐧

Registration open now!

https://t.co/D9f7H7Ovg8

[Jingdian Zhang @mitoIm50243243]

@chenweng1991 @Nature @JswLab @bloodgenes Congrats, Chen, Fantastic work! did u see mtDNA mutations 'Bottleneck' phenomenon in your datasets? is this a reason that 1/3 clones can be traced?

[Vamsi Mootha @VamsiMootha]

Hypoxia rescue (& hyperoxia sensitivity) of mito CI mutants is evolutionary conserved! Harnessing the power of worm genetics, Josh Meisel w/ ⁦⁦⁦@gary_ruvkun⁩ discovers “hypoxia mimetic” and “hypoxia resistant” mutants, yielding key mechanisms. https://t.co/h2CVsAFsGW

[Jingdian Zhang @mitoIm50243243]

Our gratitude goes to our great collaborators in and outside Rorbach lab, Molmets @MolMet_KI , CMMS, GKH, CMM-RH, and MIR. Big thanks to Dr. Xaquin Castro Dopico from Karlsson Hedestam Lab @NillaKH co-drived the discovery process of this phenomenon.

[Division of Molecular Metabolism, KI @MolMet_KI]

A new study from the Rorbach Lab, out now in @JCI_insight, demonstrates the impact that mtDNA mutations can have on the immune system. Congratulations to Jing @mitoIm50243243, Joanna, and all collaborators on this nice story!

[Jingdian Zhang @mitoIm50243243]

With supportive experimental data from several immunology research approaches, in vivo vaccination, and in vitro polyclonal activation of T and B cells via antigen receptor stimulation, etc. Please stay tuned for another one.

[Jingdian Zhang @mitoIm50243243]

Our preprint back in 2021 is finally out in JCI Insight! We found upon activation, naive T and B cells dislike/purge out high heteroplasmy mt-tRNA mutations during the development of adaptive immune response, leading to mutation burden reduction in memory counterparts.

[JCI insight @JCI_insight]

Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations: https://t.co/xOauNuwd5w
@karolinskainst
#Immunology #Metabolism

[Division of Molecular Metabolism, KI @MolMet_KI]

Congratulations Annika (@AnnikaKrger) on winning the overall oral presentation prize at #Euromit2023! Such a huge achievement and so well deserved!🌟

[Jingdian Zhang @mitoIm50243243]

@MolMet_KI @mara_mennuni FYI, mitoIM50243243 is Jingdian Zhang

[Division of Molecular Metabolism, KI @MolMet_KI]

Open postdoc position! We @MolMet_KI are looking for a postdoc to work on mitochondrial dysfunction in neurodegeneration! @mitopinionated @RobertaFilogra2

Come join us in lovely Stockholm!

Apply here:
https://t.co/HTVrMOQqlF

[Parody Nigel Farage @Parody_PM]

The entire country at the thought of Boris Johnson becoming Prime Minister again.
(sound up)

[Division of Molecular Metabolism, KI @MolMet_KI]

Many congratulations to Roberta Filograna @RobertaFilogra2, researcher in Nils-Göran Larsson's group @mitopinionated @MolMet_KI who has received a grant from the Loo and Hans Osterman Foundation to study the role of mitochondrial dysfunction in Parkinson's disease!

[Division of Molecular Metabolism, KI @MolMet_KI]

Many congratulations to Mara Mennuni, @mara_mennuni postdoc with Prof.Nils-Göran Larsson @mitopinionated who has been awarded a grant from the Alex and Eva Wallström foundation to determine the role of mitochondrial alterations in lung cancer in vivo! @karolinskainst

[Division of Molecular Metabolism, KI @MolMet_KI]

Super fun @MolMet_KI Christmas party!🎄 @mitopinionated @WredenbergLab

[Division of Molecular Metabolism, KI @MolMet_KI]

Congratulations to Joanna Rorbach for receiving two huge grants- KI consolidator and VR @Vetenskapsradet

[Taras Kreslavsky @TKreslavsky]

Modern open office space layout facilitates scientific communication...

[高遠 頼@生命科学VTuber(たかとー らい) 定期科学ニュース配信(日)🧬🔬 🥼 @takatoh_life]

Li Yu研究の動画で、動いている細胞から液胞（ミグラソーム）が明瞭に排出されているのが見ていて面白いです。

https://t.co/zOWdch01bI

[Olink Proteomics @OlinkProteomics]

Our sincere congratulations to @BrodinPetter for winning the Göran Gustafsson Prize in medicine for his pioneering analysis of the early development of the human immune system. We are proud that Olink's technology has played some role in Petter's research: https://t.co/EZK0IrZG0O

[Petter Brodin @BrodinPetter]

New work from us - Systems Immunology of #MECFS and the targeting of the vagus nerve and inflammatory reflex - an RCT of INMEST showing (~30%) symptom relief https://t.co/IqXeUm5mLu

[Jingdian Zhang @mitoIm50243243]

https://t.co/vdPe6j9jpN