Dr. Mary Jane reed

Women’s right r human rights. surgeon/critical care doc. enjoy teaching here and abroad. opinions r my own

[Dr. Mary Jane reed @mj17820]

https://t.co/2G2D0CZYto

[Critical Care Reviews @CritCareReviews]

Today's Paper of the Day is:

Magnesium in Neurocritical Care: Clinical Relevance, Status Assessment, and Practical Implications for Outcomes

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2026

[小谷祐樹 Yuki Kotani｜集中治療医 @YukiKotani5]

「右心不全について、最初に読みたい論文は？」
と聞かれたら、このNEJMの総説がオススメです。

病態生理に始まり、診断に至るまでの病歴や診察・検査所見、そして治療まで……左心不全に比べて捉えどころのない右心不全について、まず全体を理解するのに適した1本です。
https://t.co/62JC3Ucu0U

[Critical Care Reviews @CritCareReviews]

VITaCCA (vitamin C for post cardiac arrest syndrome) was presented at CCR Down Under 2025 in Melbourne and has today been published in @yourICM

You can watch the full presentation at https://t.co/kIHgOQ39kp

Paper - https://t.co/Sp06oA6IDG

@SanderRoze @intensiveblog

[NEJM @NEJM]

Fournier’s gangrene is a rare, rapidly progressive necrotizing fasciitis of the perineum, genitals, or perianal region.

Most cases begin with a known portal of entry or occur after trauma or surgical procedures in the affected region. The infection is typically polymicrobial, involving anaerobic and aerobic bacteria.

The clinical picture is characterized by rapid progression and high mortality, ranging from 7.5 to 88%. Factors contributing to higher mortality include delayed diagnosis, extensive tissue involvement, and the presence of coexisting conditions.

Prompt recognition is critical owing to the aggressive nature of the infection and associated high mortality.

SGLT2 inhibitors have been associated with an increased risk of Fournier’s gangrene. A postmarketing analysis (2013–2019) identified 55 cases among patients taking SGLT2 inhibitors. In contrast, 18 cases were reported among patients taking other antidiabetic agents between 1984 and 2019.

SGLT2 inhibitors block glucose reabsorption in the proximal renal tubules, which leads to glycosuria. The resulting glucose-rich urine creates a favorable environment for bacterial growth and infections in the perineal region, an area with multiple microbial sources. In addition, challenges in maintaining local hygiene and dryness, along with relatively limited vascularization, increase susceptibility to soft-tissue infections in this region, including Fournier’s gangrene.

Given the expanding use of SLGT2 inhibitors in clinical practice, clinicians should be aware of the association between SGLT2 inhibitors and Fournier’s gangrene, even though diagnosis is very rare. They should discuss this risk with patients and monitor for signs of infection. No clear temporal relationship exists; cases of Fournier’s gangrene have occurred years after initiation of therapy.

Learn more and test your diagnostic and therapeutic skills in “Cutting to the Chase,” a new Interactive Medical Case: https://t.co/DmpVBE3DyU

#MedicalEducation

[Journal of Trauma and Acute Care Surgery @JTraumAcuteSurg]

Read the article "Can extracorporeal cardiopulmonary resuscitation save exsanguinating trauma victims?"

https://t.co/BahWMhRmQg

[Malke Asaad @malkeasaad]

Surgeons are saving lives, but at what cost? 🩺📉

A groundbreaking 2025 JAMA Surgery study just revealed a staggering statistic: the mortality rate for surgeons is 50% higher than for non-surgeon physicians. 🤯 In fact, a surgeon's risk profile aligns closer to lawyers and engineers than to their own medical peers.

Swipe for more info to see the hidden risks and leading causes of death affecting the surgical field. 👉 Send this post to a friend in a surgical residency—we need to talk about physician wellness! 🗣👇

Need help with MATCH?
Explore our Match Application Packages and schedule a Free consultation call with our customer support team to see how we can help you!
https://t.co/DiZZb8nkmA
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#SurgeonWellness #PhysicianHealth #Surgery #MedicalCommunity #ResidencyMatch #HealthcareProfessionals

[aaron tito santiago @santiUCI]

La dosis MÍNIMA de vasopresor para suspender la nutrición ENTERAL es imprecisa. En una cohorte retrospectiva de 8055 críticos, la dosis equivalente de NE para intolerancia fue tan alta como =>0.5 mcg/kg/min…

https://t.co/P7cRLPmMKI

[BehindTheKnife @BehindTheKnife]

The debate rages! Is prehospital whole blood all it's cracked up to be?? The data has finally arrived 👇🏼

Whole Blood vs. Components: The Prehospital Debate ➡️➡️➡️ https://t.co/7HGXZfYQ72

@edbarn @DefProfEM @georgoff @DukeSurgery @DukeSurgRes

[Neurocritical Care @NeurocritCareJ]

Mainali et al: Guidelines for Neuroprognostication in Critically ill Adults with Acute Ischemic Stroke

Link: https://t.co/gRXx3NfpQQ

@neurocritical #neurocritcare

[JAMA @JAMA_current]

Low back pain is defined as pain located below the costal margin and above the inferior gluteal folds, with or without leg pain and is the leading cause of years lived with #disability worldwide, affecting people of all ages.

📝 This JAMA Review summarizes the epidemiology, pathophysiology, clinical evaluation, prognosis, and treatment of nonspecific low back pain in the outpatient setting.

https://t.co/FBOXpOrkWn

[Critical Care Reviews @CritCareReviews]

Today's Paper of the Day is:

Lung fuction impairment following cerebral ischemic stroke: Pathophysiology, mechanisms, and clinical challenges

https://t.co/JKgcYjlUQ5

Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2026

[EAST @EAST_TRAUMA]

Check out the #EASTLandmarkPapers Resource in #TraumaSurgery & #AcuteCareSurgery for heavily-cited papers as well as more recent defining papers that have changed the way patients are managed: https://t.co/boFQYc32Os

#EGS #InjuryPrevention #SurgicalCriticalCare #SurgMentoring

[Annals of Surgery @AnnalsofSurgery]

In patients with severe burns involving ≥70% TBSA, both the timing and extent of the first tangential excision were independently associated with survival, with outcomes favoring excision within 3 days and involving ≤48% TBSA. https://t.co/pPJVx42Q1X

[AAST @traumadoctors]

In this episode of Front Line Surgery: Mastering Military Trauma Care, Dr. Matt Martin emphasizes the value of mentorship when facing unfamiliar pediatric trauma cases. He reminds military surgeons that reaching out to trusted mentors can provide critical guidance and support—even in the most challenging situations.

Now available on all streaming services

[NEJM @NEJM]

In patients with cardiac arrest, reperfusion after circulation is restored can cause brain damage. Whether a conservative oxygen strategy could reduce injury caused by reperfusion is uncertain. Research findings from the LOGICAL trial are summarized in a new Quick Take video. https://t.co/x7ZMXWq5Pr

[Journal of Trauma and Acute Care Surgery @JTraumAcuteSurg]

Read the article "Essential considerations in the use of improvised tourniquet: An editorial on “An American College of Surgeons Committee on trauma stop the bleed guideline on the use of improvised tourniquets for trauma patients with life-threatening extremity hemorrhage 2025”"

https://t.co/ZWzbN9Jq99

[BehindTheKnife @BehindTheKnife]

THE CRITICAL VIEW OF SAFETY 🚨🦺

[CHEST @accpchest]

A #journal_CHESTCritCare How I Do It article presents three patient scenarios to illustrate the management of anemia in hemodynamically stable critically ill patients.

Read more: https://t.co/5l2QtjqShr
#MedEd #JournalCHEST #CriticalCare #CritCare

[Rosario Losiggio, MD @LosiggioRosario]

#CCR26 is over!
12 outstanding RCTs presented!

😍Save and share this figure to keep a concise overview of the key information!

🎨 Color coding reflects my personal overall interpretation:
🟢 Benefit
⚪ No difference
🔴 Harm

Few practice-changing results but plenty to discuss!

[NEJM @NEJM]

Presented at #CCR26:

Among adults with septic shock, the use of restricted fluids and early vasopressors did not result in more days alive and out of the hospital through day 90 than the use of liberal fluids and later vasopressors. Full ARISE FLUIDS trial results: https://t.co/GsimTBtR7c

@CritCareReviews