Moiz Masood Sultani

Filmmaker (walked the Red Carpet at Cannes Film Festival). Designer. Loves art, history, cooking, dancing, Yoga, Stoicism, Kabbalah, Taoism, Buddhism & Sufism.

[Historic Vids @historyinmemes]

“A homeless man died of hunger but there was food at his funeral.”

- Oscar Wilde

[Master Metabolism @lowmegatron]

Endothelial dysfunction is associated with hypothyroidism, improves with thyroid hormone (T3), and worsens when thyroid hormone is withdrawn.

Endothelial dysfunction is when the thin lining of your blood vessels stops working properly, losing its ability to relax and widen vessels normally. It’s an early step toward high blood pressure, atherosclerosis, and heart disease.

“Hypothyroidism in women is associated with microvascular endothelial dysfunction, even after adjusting for confounders, and may explain some of the increased risk of cardiovascular disease in these patients.” ¹

“(Thyroid hormone) T3 exerts direct and acute effects on the resistance vessels by enhancing endothelial function and norepinephrine-induced vasoconstriction. The data may help clarify the vascular impact of the low T3 syndrome and point to potential therapeutic strategies.” ²

“Endothelial function was transiently impaired in (differentiated thyroid cancer) patients at short-term hypothyroidism (thyroid meds stopped) state during the RAI therapy, and immediately returned to the initial state after restoring TSH suppression therapy (restarting thyroid meds, levothyroxine).”

¹ Hypothyroidism Is Associated With Coronary Endothelial Dysfunction in Women
² Acute effects of triiodothyronine on endothelial function in human subjects
³Transiently impaired endothelial function during thyroid hormone withdrawal in differentiated thyroid cancer patients

[🌞HELIOS🌞 @helios_brah]

Greets from Germany where they just released a 286 page (!) book documenting tree damage from Celltower/RF radiation

That is A LOT of tree damage, lmao

[⚡️ The Blue Light Diet ⚡️ @BlueLightDiet]

Chronic circadian rhythm disruption gives you fibrosis.

Artificial light at night screws your sleep but can also scar your liver, kidneys and lungs.

The paper shows peripheral clocks in cells (like hepatic stellate cells in the liver or alveolar fibroblasts in the lungs) get effed up by light at the wrong time. This speeds up TGF-β signaling, collagen dumping and chronic inflammation and leads to stiff, failing organs.

Some studies show fibrosis (excess scar tissue) contributes to 45% of deaths in developed countries.

Artificial light at night scars your organs.

Better start following the BLD or something similar, bro.

[Camus @newstart_2024]

Joe Rogan ditched his reading glasses after using red light therapy.

Gary Brecka shared this on Diary of a CEO — after a few weeks with a full red light bed, Rogan’s eyesight improved so noticeably he no longer needs readers. And that’s just the beginning.

Brecka explained the science: specific red and near-infrared wavelengths (photobiomodulation) enter your mitochondria, kick out nitric oxide, and force oxygen in.

This jumps cellular energy production from 2 ATP per cycle… to 36. Sixteen times more efficient. The ripple effects hit inflammation, skin, brain health, and recovery hard.

[Master Metabolism @lowmegatron]

Low blood sodium (hyponatremia) can be a result of hypothyroidism.

“We report a case of a 62-years-old female with the symptoms of severe hyponatremia like altered mental sensorium with a serum sodium level of 110 meq/l. After ruling out other causes, a final diagnosis of hypothyroidism was made. On treating hypothyroidism the symptoms of hyponatremia were resolved. Therefore, thyroid stimulating hormone determination is mandatory during the evaluation of hyponatremia. And, those patients should be treated with fluid restriction and treatment of hypothyroidism.”

Hyponatremia symptoms progress as sodium levels drop:

Early symptoms:
Nausea and vomiting
Headache
Fatigue and lethargy
Muscle cramps or weakness

Moderate symptoms:
Confusion and disorientation
Irritability
Swelling (hands, feet, face)

Advanced symptoms:
Seizures
Loss of consciousness
Respiratory distress
Coma (can be fatal if untreated)

"Low thyroid function involves reduced formation of carbon dioxide, and the body fluids dont retain as much sodium as in normal individuals. Both urine and sweat tend to contain abnormally high sodium concentration in hypothyroidism. Because CO2 is central to the regulation of pH, and hydrogen ion excretion (acid urine) is one mechanism involved in sodium retention, the CO2 deficiency of hypothyroidism is probably closely connected with the inability to retain adequate sodium." — Ray Peat

[ALLATRA @allatra_org]

Microplastics are already inside us and they are affecting our health. Professor Ragusa explains where the real problem lies and why it's not just about plastic. Are you ready to find out what each of us needs to do to solve this problem?

For more details, follow the link.

[Master Metabolism @lowmegatron]

Vitamin K2 can help rebuild bone and decalcify soft tissue.

“Vitamin K2 treatment effectively prevents the occurrence of new fractures...” 🧑

“This systematic review suggests that supplementation with phytonadione and menaquinone-4 (K2 MK-4) reduces bone loss. In the case of the latter, there is a strong effect on incident fractures among Japanese patients.” 🧑

“45 mg (K2 MK4) was the minimum effective dose for improving bone mass parameters evaluated by microdensitometry and/or single photon absorptiometry in postmenopausal women with osteoporosis.” 🧑

“It may be suggested that a high dose of vitamin K2 suppressed experimental calcification of soft tissues induced by vitamin D2. Therefore, a pharmacological dose of vitamin K2 might have a usefulness for the prevention and treatment of arteriosclerosis with calcification.” 🐁

“This is the first study in rats demonstrating that arterial calcification and the resulting decreased arterial distensibility are reversible by high (K1 or K2). intake.” 🐁

Ref:
PMID: 10750566
PMID: 16801507
PMID: 24841104
Clinical evaluation of soft capsule menatetrenone (Ea-0167) in the treatment of osteoporosis. Late Phase II Dose Study
PMID: 8698544
PMID: 17138823

[Anish Moonka @anishmoonka]

Look down at your big toe. If it used to have hair on it and now it doesn't, blood is probably struggling to reach down that far. Doctors have used this as an early warning sign for decades, and the test that confirms it takes five minutes.

Hair grows because tiny blood vessels feed each follicle with oxygen and nutrients. When fatty deposits clog the arteries higher up your leg, blood barely makes it to your toes. The follicles starve and shut down. Hair falls out and stops coming back.

This is called peripheral artery disease, or PAD, and roughly 200 million people worldwide have it. Mayo Clinic, Johns Hopkins, and the UK's NHS all list bare feet and lower legs as a recognized warning sign. More than half of them feel completely normal in their legs. The hair on their toes is often the only thing giving the disease away.

Hair loss alone doesn't mean you have PAD. Sock friction, age, and hormones can thin foot hair on their own. Doctors look at the bigger picture: shiny tight skin on the calves, cold feet that won't warm up, cuts that take forever to heal, a weak pulse behind your ankle bone, slow-growing toenails. If a few of those signs are happening at once, the hair loss starts to mean something.

The same fatty buildup clogging your leg arteries usually clogs the ones feeding your heart and brain. People with PAD are roughly twice as likely to die of a heart attack or stroke over the next ten years as people without it. Even when they have zero leg symptoms. One long study followed silent PAD patients for a decade and found that only 3 out of every 5 were still alive at the end.

The test is called the Ankle-Brachial Index. A nurse takes your blood pressure at your ankle, then at your arm, and divides one by the other. If the ankle reading is much lower, blood is struggling to reach your feet. The cutoff doctors use is 0.9. Five minutes, doesn't hurt, costs almost nothing.

What turns this from "probably nothing" into "go get checked" is the usual cardiovascular crowd. Smoking, diabetes, high blood pressure, high cholesterol, over 50. If a few of those describe you and your toes have gone smooth, ask your doctor for the ABI on your next visit. If they look puzzled, say "ankle blood pressure compared to arm blood pressure." They'll know.

Your toes give away clogged arteries before anything else for one reason. They're at the end of the line.

[Nexo Supremo @VargasKevi70887]

Vello en los dedos de los pies: una pequeña pista sobre tu salud metabólica y cardiovascular.

Puede parecer un detalle insignificante, pero clínicamente revela información crucial sobre cómo está funcionando tu cuerpo por dentro.

Si no tienes vello en los pies, esto es lo que tu cuerpo intenta decirte: 🧵

[Historic Vids @historyinmemes]

A woman takes part in a protest against wealth inequality in North Carolina during the 1930s.

[Dan Go @CoachDanGo]

The one exercise I see in people who live the longest:

Walking.

Getting 8000 steps has been associated with up to a 50% reduced rate of mortality.

It protects the brain through neuroplasticity.

It’s the most underrated exercise on the planet.

[Rusty ⚡️: Solar Powered ☀️ @ze_rusty]

We're an electromagnetic being living inside a Magnetic Earth.

A 2008 study found that during heightened geomagnetic activity, men secreted significantly less melatonin

but ONE DAY LATER

The strongest link appeared 15–33 hours after the magnetic spike.

[Massimo @Rainmaker1973]

Your tattoo isn’t just decorative ink: it’s a permanent trigger that keeps your immune system locked in a lifelong cycle of chronic inflammation.

As soon as the ink is injected into your skin, your body recognizes the pigment particles as foreign invaders. Immune cells called macrophages immediately swarm the area and attempt to swallow them up. But because they can’t actually break down the ink, the macrophages eventually die, releasing the pigment back into the surrounding tissue — only for a new wave of macrophages to arrive and repeat the process.

This endless cycle is what keeps the tattoo permanently visible, while also maintaining a state of ongoing, low-level inflammation in the skin.

Over time, some of these ink particles migrate through the lymphatic system and accumulate in the lymph nodes, placing constant stress on the body’s defense mechanisms. Emerging research suggests this internal ink buildup may interfere with normal immune function, potentially reducing the effectiveness of certain vaccines, including mRNA types. Additionally, many tattoo inks contain heavy metals like nickel and cobalt. Combined with the chronic inflammation, this has been linked to a modestly elevated risk of lymphoma and skin cancer.

While tattoos remain a powerful form of self-expression, they represent a complex, decades-long biological conflict between your immune system and foreign substances embedded in your skin.

[Nielsen, C., Jerkeman, M., & Jöud, A. S. (2024). Tattoos as a risk factor for systemic lymphoma: A population-based case-control study. eClinicalMedicine]

[Simmo @yoursimmo11]

The man who discovered vitamin C and won the Nobel Prize for it distinguished pure ascorbic acid from the full vitamin C complex...

But please, keep sending chemistry textbooks.

- Whole-food vitamin C contains ascorbic acid plus bioflavonoids, tyrosinase, ascorbinogen, Factor K, Factor J, Factor P, and copper. The isolate is one fragment.
- Synthetic ascorbic acid is manufactured from GMO corn dextrose, hydrogenated, processed with acetone and hydrochloric acid.
- In isolation it can act as a pro-oxidant, generating hydrogen peroxide in tissues. The whole-food complex does not do this.
- Bioavailability and tissue retention differ dramatically between the isolate and the food matrix.
- "Everything is chemicals" is both true and meaningless. Cyanide is a chemical, mercury is a chemical, and structure plus source decide biology (by that logic, pure fructose equals fruit, ethanol equals wine, and casein equals milk).

You weren't taught chemistry. You were taught marketing.

[Paul Saladino, MD @paulsaladinomd]

Botox in the face may reduce orgasm intensity in women, and it can affect depression scores depending on where you get injected. (PMID 30283017)

36 women: 24 got actual Botox and 12 got other cosmetic treatments as controls. A significant drop in the orgasm domain for the Botox group was found on the Female Sexual Function Index. No change in the controls.

"Reducing the ability to make the facial expressions associated with sexual pleasure leads to a reduction in the reported feeling of pleasure associated with it. The results suggest that the facial expressions do not occur simply to communicate pleasure to a partner but they are an integral part of the feeling of pleasure and are important in the process of achieving orgasm."

The results for depression went in two different directions:

Injecting the crow's feet (laugh lines) worsened depression scores.

Injecting the glabellar frown lines improved them.

Small sample size, and these findings haven't been replicated or refuted yet.

I still think this is enough to make you think twice about Botox in the upper face, especially frown lines, crow's feet, and laugh lines.

More research is needed, but this is pretty concerning.

[mitsuri @0xmitsurii]

Psychiatrists when asked how many patients have they cured.

[Magnus Vigsø @MagnusVigso]

foods of the abrahamic religions:

[Dan Go @CoachDanGo]

Steve Jobs never let his kids touch an iPad. Bill Gates banned phones until age 14.

Chris Anderson, ex-Wired editor, called screens "more dangerous than crack."

And I agree. We used to let our oldest use an iPad and saw an increase in behavior issues. We stopped that and don't let our kids use smartphones or iPads.

If they do they're using a Daylight, which is a screen built without blue light. This turns down the addictive factor.

People in tech know exactly what these products do to a developing brain. They literally engineered them to be addictive.

I'm not saying to not let your kids near these things because every situation is different.

But the mounting evidence is damning. If I want my kids' brains to develop in a healthy way, I'm keeping them off til they get older.

[Ace @MrAcezzz]

The reason it works is the protein structure is small enough to actually absorb intact, no gut barrier breakdown needed, it hits systemically.

Brain inflammation is a metabolic problem at its core and camel milk addresses it at that level.

People are out here chasing copelements while this has been a household staple in the middle east forever.