Are pseudogenes just "genomic fossils"? Our latest preprint says no! By analyzing 244 high-quality vertebrate genomes from VGP, we show that processed pseudogenes (retrocopies) are actually dynamic substrates for evolutionary innovation. Full study here: https://t.co/NCoe57hMRh
Honored to share that the study we contributed to has won the 16th Octávio Frias de Oliveira Award in the Oncology Research category in Brazil! It’s a special joy to receive this award for the second time (first in 2015). #BrazilianScience#Oncology
O novo post do blog é sobre meu último paper em uma linguagem acessível! ✔️
#Transposons alteram a expressão gênica e podem impactar na resposta à terapia com cisplatina em câncer de ovário. 🧬➰🧬
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https://t.co/xympYRmEls
So excited to share our paper (in collab with @GalanteLab) revealing the importance of considering the entire spectrum of transcribed elements (transposons 🧬➰🧬 in particular) in the understanding of complex models like cancer response to treatment! 🤩
https://t.co/1n29pQmu6s
So excited to share our story revealing structures, functions and adaptations of the human LINE-1 retrotransposon, an ancient genetic parasite that has written 1/3 of the human genome and is implicated in cancer, aging, & autoimmunity. Now out in @Nature https://t.co/wyo0fTUn4e
TRANSPOSABLE ELEMENTS ALTER GENE EXPRESSION AND MAY IMPACT RESPONSE TO CISPLATIN THERAPY IN OVARIAN CANCER
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My latest work, collab. with @GalanteLab, is out as a preprint! We investigated TEs in ovarian cancer cell lines response to cisplatin.
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https://t.co/TUK0bGYVl8