#ASH23 Kumar et al @MSKCancerCenter update BOVEN: obinu/ven/zanubrutinib in TP53mut mantle cell lymphoma
n=25, med follow-up 16 months
ORR 95% CR 88% with 16-month PFS and OS rates 75 and 87%
encouraging data for high risk disease
great effort
#lymSM
https://t.co/U5BPYY6nNG
ASH 2022 Thought 12 - We are curing hematology malignancies. As for me, I will continue to work hard with my patients, their families, with industry colleagues and academic collaborators to accelerate the cure of Mantle Cell Lymphoma. We are within striking distance!
ASCT had superior PFS and OS (!!!) than R-DeVIC consolidation. Confirms what we have suspected. PROs were collected and eager to looking at those in the ASCT arm as well. #ASH22#lymsm#bmtsm
2/2
I interview Dr. Birhiray who asked a critical & provocative question at yesterday’s @ASH_hematology #ASH21 session.
Why allow an abstract at a plenary if enrollees at the study presented do NOT represent US demographics?
Hear proposed solutions. #HealthcareUnfiltered
Three police officers went to an *elementary* school in Tennessee & arrested four Black girls.
One girl fell to her knees. Another threw up. Police handcuffed the youngest, an 8 yo with pigtails.
Their supposed crime? Watching some boys fight — and not stopping them. (THREAD)
With dozens of researchers at Yale, Stanford, Berkeley and IPA and several other organizations, we ran a cluster randomized trial involving almost 350,000 people and 600 villages in Bangladesh to assess the impact of community masking on COVID.
@nataliexdean@NateSilver538 I think he is just saying that the results of this study have implications for other studies that are trying to estimate vaccine efficacy, unless they account for prior infection. That’s my takeaway at least.
We updated our #COVID19 FAQs in response to the @US_FDA amending the EUAs for both the Pfizer-BioNTech and the Moderna COVID-19 vaccines to allow for the use of an additional dose in certain immunocompromised individuals.
Click here to read: https://t.co/KfxRjqLY6F | #ASHCOVID
@AaronGoodman33 I believe long term follow up presented at ASH 2008 showed an OS benefit for ASCT in MCL CR1. However, this was pre-rituximab. https://t.co/VI3Y9jhKR3
Worried patients are asking their doctors these questions. Need CDC guidance soon
1) I'm immunosuppressed. Should I check antibody levels?
2) I'm immunosuppressed. My doctor checked antibodies. I have none— after 2 doses. Can I get a booster?
3) I got J&J. Can I get a booster?
We're excited to welcome Dr. Marcus Messmer (@mrmessmer) to our Hematology/Oncology team at Fox Chase!
More about his background and experience: https://t.co/Lkh0xcvsvy
Hospitals all around the country pay lip service to pt and family centered care, while enforcing non-scientifically based visitor restrictions
You can go to Target with the whole family but grandma has to be alone while getting her new cancer diagnosis
@HopkinsMedicine
Excited to announce our Chief Fellows for the upcoming academic year:
Dr. @parulagarwalmd, Dr. @JennaCanzoniero, and Dr. Daniel Zabransky.
Look forward to all the amazing things they will do!
I would like to share the story of how a patient with cancer came up with the idea for a randomized trial, & how listening to him saved a lot of lives.
1/ In 2002, I had just completed a randomized trial with the notorious drug thalidomide for the cancer, multiple myeloma.
Impact of Clinical Trial Eligibility Criteria in Patients With Diffuse Large B-Cell Lymphoma: An important analysis from our colleagues at Mayo and Iowa. Our new @SWOG NCTN trials are attempting to address this. @ASCO_pubs@MaurerStats https://t.co/KQy7UlHM5e