Last paper for 2024. Nice work by @mrwaas on proteomics of HNSCC tissues to identify novel biomarkers within the N0 population. Great collaboration with @laillesuhnrese1 and support from many colleagues @PMResearch_UHN
Checkout our new paper, describing a simple method to analyze low amounts of flow sorted cells by @mrwaas and team
Droplet-based proteomics reveals CD36 as a marker for progenitors in mammary basal epithelium: Cell Reports Methods https://t.co/FXHzafuH6g
Targeted Mass Spectrometry of Longitudinal Patient Sera Reveals LTBP1 as a Potential Surveillance Biomarker for High-Grade Serous Ovarian Carcinoma | Journal of Proteome Research https://t.co/qgxtTIWZhr
We have a job opening for a Research Associate/Mass Spectrometrist in the lab. If you are interested, please apply through the link below. Four mass spectrometers to work with and lots of cool clinical proteomics and cell surface marker projects to work on.
Introducing DROPPS!
Here's our preprint that describes an accesible approach to low input proteomics and how we applied it to generate some interesting biological insights (1/x)
https://t.co/cBhdAWgy4a
@NanoPOTS_SCP@mathepan We identify and validate CD36 as a marker of high mitochondrial activity with enhanced clonogenicity in the basal epithelium and uncover that this may be related to CD36's ability to rewire metabolism towards fatty acid utilization. (6/x)