@zbinney_NFLinj@gcaw Correct me if I am wrong, but sensitivity and specificity do not change with prevalence of disease in the population (as does positive or negative likelihood ratio)
@jbenton@NAChristakis The timeline of symptoms to death in this case doesn’t seem to fit the usual illness script for covid (gradual decompensation over the course of 7-8 days) as opposed to a sudden death. Without a confirmed positive test, no way to say this wasn’t a pulmonary embolism
@NAChristakis@mlipsitch@trvrb@florian_krammer@bimald@venkmurthy@jflier Physician in NYC here. Have you considered the potential utility of prophylaxing entire nation with hydroxychloroquine (minimal side effects)should the pending clinical trials show a benefit in patients after high risk exposure? Could be a poor man’s vaccine in a way