Mike_Mqt

Nanopore sequencing,
targeted sequencing (adaptive sampling),
Flowcell slayer,
PhD Student,
Bioinformatics

[Mike_Mqt @mult1fractal]

@nanopore

[Rasmus Kirkegaard @kirk3gaard]

With the P2S joining the long list of abandoned @nanopore products in favour of the expensive P2i it becomes clearer that the #anyone #anywhere vision is lost...

[Martin Hölzer @martinhoelzer]

🚨 Preprint!

We've adapted SC2 wastewater surv to track the 2022 #mpox outbreak in Germany using a novel NGS panel 🧪

✅ 90% MPXV genome coverage
🧬 Specific mutations
📍 Wastewater = stigma-free surveillance

Led by - @Lackner_TUDa, check it out:
🔗 https://t.co/J6jqrhX0cN

[Tinatin(i) Tchatchiashvili @tina_tch]

Thrilled to share our new publication 🎉 🥳 We demonstrate that metabolic-based probes (CAM/TMA-DPH) outperform membrane integrity assays (SYTO9/PI) in precision and consistency for biofilm viability assessment across diverse bacterial species.

[Tinatin(i) Tchatchiashvili @tina_tch]

🎉 📢Excited to announce my paper, "PEG-PLGA nanoparticles deposited in Pseudomonas aeruginosa and Burkholderia cenocepacia", is published! https://t.co/PIIGKI198y
This study is highlighting PEG-PLGA's potential for effective drug delivery in Gram-negative bacteria.

[Tinatin(i) Tchatchiashvili @tina_tch]

Happy to be part of #TargetingPhageTherapy2024 conference in beautiful Malta and meeting new people from #phagecommunity and my former colleagues from #Eliavainsitute

[Phage Literature @phagebot]

Bacteriophage-mediated decolonization of Klebsiella pneumoniae in a novel Galleria mellonella gut colonization model with Enterobacteriaceae https://t.co/Mw0IeI5psD

[Mike_Mqt @mult1fractal]

#riseandshine
#NanoporeConf
@gcloudChris
@maralohde
Ready for new knowledge

[nobody @phiweger]

great colab with @martinhoelzer @gcloudChris @mult1fractal -- thx guys!

[Oxford Nanopore @nanopore]

We are pleased to announce a new protocol explaining how to recover a DNA library mid-sequencing run. This protocol has been developed to enable precious samples to be recovered and transferred to a new flow cell for continued sequencing. Learn more: https://t.co/n18duZFM6B

[European Virus Bioinformatics Center @EVirusBioinfC]

What the #Phage: an easy-to-use and parallel multitool approach for phage prediction combined with an #annotation and #classification downstream strategy. [co-authored by EVBC members @mult1fractal @martinhoelzer @DrPletz @phiweger R. Ehricht] https://t.co/wqNww6wsbs

[InfectoGnostics Forschungscampus / Research Campus @InfectoGnostics]

Mitarbeiter für Wissenschaftskommunikation (w/m/d) gesucht
https://t.co/mVOr9JrtyT

[InfectoGnostics Forschungscampus / Research Campus @InfectoGnostics]

"What the Phage?" In diesem Artikel wird ein skalierbarer Arbeitsablauf für die Identifizierung und Analyse von #Phagen sequenzen vorgestellt @UKJ_Jena @nanozoo https://t.co/WAcWFbspMv

[nobody @phiweger]

People asked for documentation, so "faltwerk" -- a python library to explore protein structures spatially -- now lives on readthedocs, and v0.5 has even better support for protein complexes -- https://t.co/CeWO0u1roQ

[Mike_Mqt @mult1fractal]

@NickdeVrij @TJesse62 Could be that there is a small bubble where the measurement is happening.
You could try to extract 25 yl via priming port and check again
I got this hint from the customer support when we had similar issue

[Christian Brandt @gcloudChris]

Our case report highlights how rapid @nanopore sequencing helps us out in our Hospital @UKJ_Jena when encountering inconclusive VITEK results. We only needed 7.5 h from the isolate to sequence results using standard kits and sequencing protocols.
https://t.co/eDc6HAR3mO

[Benjamin Callahan @bejcal]

Our latest work led by @mikemc423 on bioRxiv goes deep on "Implications of taxonomic bias for microbial differential-abundance analysis": https://t.co/JIuwpvteoh

Metagenomic sequencing is biased. When are differential abundance (DA) results still valid?

#NCStateMicrobiome 1/

[bioRxiv Bioinfo @biorxiv_bioinfo]

VIRify: an integrated detection, annotation and taxonomic classification pipeline using virus-specific protein profile hidden Markov ... https://t.co/UWTCOfK41x #biorxiv_bioinfo

[nobody @phiweger]

I went down this rabbit hole of _spatial_ analysis of protein structures, now easily generated using eg #alphafold. Interestingly, there were many annoying steps that got in the way, and I also wanted something workflow-compatible. Therefore: https://t.co/NVb5xZmPCM

[Phagepapers @phagepapers]

Identification of bacteriophage genome sequences with representation learning https://t.co/oCkSHCpe7I