Ben Munro

Postdoc in the Larsson lab @molmet_ki @karolinskainst Interested in mtDNA regulation in health and disease 🧬

[Human Molecular Genetics @hmg_journal]

Deoxynucleoside supplementation ameliorates the disease associated phenotypes in a zebrafish model of RRM2B mtDNA depletion syndrome
https://t.co/mSZMVJU2at

[Ben Munro @munromit]

We're looking for a postdoc! 🧑‍🔬 If you're interested in mitochondrial genetics, have a look below! 🧬🔬🥼 Feel free to ask any questions.

https://t.co/ufQ7bkM2De

[Ben Munro @munromit]

Big thanks to everyone involved, especially the animal technicians, and Declan, who spent a summer internship meticulously analyzing zebrafish touch-evoked escape response data.⁣ A very tedious (but vital!) part of the work! 🐟

[Ben Munro @munromit]

🧬 New paper! We nudge the science forward surrounding deoxynucleoside supplementation & mitochondrial DNA depletion syndromes (MDDS).⁣ We show, for the first time in vivo, that deoxynucleoside supplementation can mitigate effects of RRM2B mutations.🔗 https://t.co/WLHSOSrhob

[Ben Munro @munromit]

This proof-of-concept study highlights that deoxynucleoside supplementation can mitigate RRM2B dysfunction in vivo. More challenges remain in bringing this to patients; determining effective delivery methods, combinations, and dosing of deoxynucleosides is vital!

[WredenbergLab @WredenbergLab]

Interested in mitochondrial biology? We are looking for an enthusiastic PostDoctoral fellow and PhD student to join our group in Stockholm. @mitojobs @MolMet_KI
For the PhD position: https://t.co/9ZsHC4RbqJ
For the PostDoc position: https://t.co/MOBdoUy10K

[Roberta Filograna @RobertaFilogra2]

🚨PostDoc Alert!
We are looking for an enthusiastic and driven #PostDoc to study the role of mitochondrial dysfunction in neurodegenerative diseases.
Join my research group @MolMet_KI within @karolinskainst! #Mitochondria #Neurodegeneration #MitoJobs

https://t.co/ksqC0jgsiy

[WredenbergLab @WredenbergLab]

We are excited to share our latest work on mechanisms that protect from mitochondrial dysfunction. Thank you to all collaborators and the 4th anonymous reviewer for supporting us. @labs_mann @NatureComms @metaboflo
https://t.co/xLNyW00oil

[WredenbergLab @WredenbergLab]

We have 1-2 PostDoc positions for enthusiastic researchers interested in mitochondrial biology. Apply here. #mitochondria #mitojobs
https://t.co/tOv2e05PHF

[Nils-Göran Larsson @mitopinionated]

New study from us:
https://t.co/GioeqFmsKo
High mtDNA copy number promotes lung cancer growth in the mouse, whereas mtDNA depletion in tumor cells reduces tumor growth. This tumor-intrinsic role for mtDNA can be exploited for development of future lung cancer therapies.

[Diana Rubalcava @RubalDiana]

🚨Mitochondrial research out🚨 Our latest work on the synergy between LRPPRC and SLIRP for maintaining mtDNA gene expression in vivo is now published! 🧬 Free-access link to the article: https://t.co/uEqZ2l9757

[Robert Pitceathly @RobPitceathly]

🚨Advance article alert - mutant PTPMT1 impairs cardiolipin metabolism causing human disease. Fantastic collaborative effort across several continents!

Biallelic PTPMT1 variants disrupt cardiolipin metabolism and lead to a neurodevelopmental syndrome https://t.co/FMuQouUZv0

[Nils-Göran Larsson @mitopinionated]

New paper from us on the in vivo role of the LRPPRC/SLIRP protein complex and its crucial role in mammalian mtDNA gene expression:
https://t.co/qDhEd7WCtN
Congratulations @RubalDiana for great work! Thank you to all coauthors for a very nice collaboration.

[Ben Munro @munromit]

@intheOR @HorvathLab Thanks Oscar! 😀

[Ben Munro @munromit]

After 7 years, yesterday was my last day in @HorvathLab . Thanks to all those past and present who made my time a special one! I'll miss everyone!

[Ben Munro @munromit]

@mkfrison92 @HorvathLab Grazie Michele!

[Ben Munro @munromit]

@GibbStem @HorvathLab Thanks George!