Nadia Othonos

Endocrinologist

[Europe PMC articles @EuropePMC]

New from #The_MRC https://t.co/v9nk1vhjL1 11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial.

[Nadia Othonos @Nadia_Othon]

@MickOReilly1980 @NatureComms Thanks Mick!

[Nadia Othonos @Nadia_Othon]

I am thrilled to share our paper “11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial”, published this week in @NatureComms https://t.co/KYwJJ6mgFd

[Nadia Othonos @Nadia_Othon]

@afrabb @NatureComms Thank you Afroze! Yes the results are promising!

[Craig Webster @craig_webster]

Glad the mass spec method we developed (prednisolone) still finds its uses and very grateful for the recognition of that by the Oxford team

https://t.co/oA1nhI7m2V

[Daniel J Drucker @DanielJDrucker]

11β-HSD1 inhibition with AZD4017 is proposed as a strategy to attenuate glucocorticoid-associated side effects on blood pressure, glucose, bone, and lipid metabolism, assessed here after 7 days in healthy men @NatureComms https://t.co/f3e31HuYJT

[Nadia Othonos @Nadia_Othon]

@Nikolaou_Nik1 Thank you Niko!!

[Tom Marjot @tom_marjot]

Is this the beginning of the end for iatrogenic Cushing's?

11β-HSD1 inhibitor + Pred kept anti-inflammatory effects but stopped the bad stuff (hepatic IR, bone loss, dyslipidaemia)

Worth a look by anyone prescribing steroids
#rheumtwitter #livertwitter

https://t.co/X71oY48Wln

[Nadia Othonos @Nadia_Othon]

@DrKanaris @NatureComms Thanks Conno m!

[Nadia Othonos @Nadia_Othon]

Thank you to all collaborators. @OCDEM @GroupTomlinson @RiccardoPofi @ahmadmoolla @Nikolaou_Nik1 @Ani_Arvaniti

[Nadia Othonos @Nadia_Othon]

Why is owning a gun considered a right in the US but healthcare isn’t? 🤨#GunControl

[Nadia Othonos @Nadia_Othon]

Congratulations @Nikolaou_Nik1 for this outstanding achievement!! Well deserved!!

[Tomlinson Group @GroupTomlinson]

Many congratulations to Dr. Nikolaos Nikolaou @Nikolaou_Nik1 for being awarded a @ESEndocrinology Young Investigator Award for his work on AKR1D1 as a driver of metabolic dysfunction and HCC in NAFLD! Nikolaos will present his abstract in Milan in May 2022. @RDMOxford @OCDEM

[CUH_Diabetes @CUH_Diabetes]

Excited to announce #clinical implementation of #ClosedLoop for #inpatients with #T2DM @cuh_nhs! Funded by @ACTcharity, this clinical pilots led & implemented by clinical staff. Our first patient states "Its a wonderful device!" #camdiab @CUH_Pharmacy @Andrealake1984 @DSNforumUK

[Nikolaos Nikolaou @Nikolaou_Nik1]

Well done @appanna_nathan and team! @GroupTomlinson @KarlStorbeck @OCDEM

[Nadia Othonos @Nadia_Othon]

Some of my fondest memories from school were from #DukeofEdinburghaward expeditions. #RIPPrincePhillip

[Nadia Othonos @Nadia_Othon]

Congratulations Niko! Well done to all those involved. @appanna_nathan @Ani_Arvaniti @gatheringcole @GroupTomlinson

[Nikolaos Nikolaou @Nikolaou_Nik1]

Publication Alert: Super excited to share my first senior/corresponding author manuscript describing the differential activity and expression of human 5β-reductase splice variants, published today at @JMolEndo! @OCDEM @GroupTomlinson @MetabolicNW https://t.co/1ogcJM6E5n

[Nadia Othonos @Nadia_Othon]

Vaccinated today! Very grateful to all the scientists that made this possible! 🙏🙏

[Nadia Othonos @Nadia_Othon]

Congratulations Nick!! Excellent work!

[Nikolaos Nikolaou @Nikolaou_Nik1]

The first of 2021! Happy to share our latest review manuscript describing the role of 5-reduction in physiology and metabolic disease. @GroupTomlinson @Hodson_Group @OCDEM @MetabolicNW @RDMOxford Please check: https://t.co/3al5CSQntb

[Nadia Othonos @Nadia_Othon]

Thesis submitted! 😁

[Nadia Othonos @Nadia_Othon]

Congratulations Riccardo! Fantastic piece of work! 👏🏻

[Riccardo Pofi @RiccardoPofi]

OUT NOW! Discover the newest insights on the natural history of diabetic cardiomyopathy. Independent from glycemic status, it progresses involving the extracellular matrix proteins and viscoelastic properties of diastolic return #diabetes #HFpEF #JACCIMG
https://t.co/IKoxkJfw03