Can we use Dual β-lactam?
One example is Cefazolin and Ertapenem, a synergistic combination used in the treatment of persistent MSSA bacteremia
Mechanism 👇
Can you think of other examples for dual β-lactam? #IDXposts
Need help setting up the O2 devices for patients with asthma or COPD exacerbations? This table should be quite helpful. 🎩 tip to the authors.
https://t.co/4Ise540F2X
🫁#ARDS severity based on oxygenation impairment does NOT reflect respiratory mechanical properties & MV setting, VILI prerequisites/determinants. Respiratory support should be tailored more closely to lung mechanics/CO2 clearance rather than oxygenation🔓https://t.co/qxouoWB5Zb
Managing bleeding after cardiac surgery should not be over complicated. Here’s a transfusion algorithm that can help guide us and allow us to be better stewards of our precious resources. 🎩 tip to the authors.
https://t.co/4Ise540F2X
Today's Paper of the Day is on the management of pregnant trauma patients
https://t.co/JKgcYjlUQ5
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2024
Resuscitation fluids, @ESICM guideline 🧵1/2
💦 for volume expansion use crystalloids vs albumin in critically ill pts in general, in #sepsis, ARF & periop + if risk for bleeding
💦 isotonic saline vs albumin in TBI & albumin vs crystalloids if cirrhosis
🔓https://t.co/g6P9uyGuet
Hemostasis testing in #ICU to evaluate
🩸thrombotic &
🩸bleeding disorders
with conventional/second line tests + VETs may improve individualized protocols leading to more targeted/effective interventions ⬇️ unnecessary transfusions/complications. #FOAMcc
🔓https://t.co/JXJ202FSWu
Guiding resuscitation on serial lactate measurements? Not an accurate biomarker of hypoperfusion. However integration with clinical phenotyping + peripheral perfusion assessment could better individualize strategies
🔓https://t.co/WbltVYacWC
Refers to
🔓https://t.co/V0gpQ0U0yU
Are you still looking for for interesting manuscripts for your Journal Clubs on critically ill patients?
Here are 25 further ideas
➡️All 2023 RCTs
➡️All @JAMA_current
6 showing benefit and 6 showing harm
In order of personal perceived importance
1/
🔴"Quando non c'è certezza del futuro bisogna vivere più intensamente il presente
È come se avessi strappato alla mia fine una manciata di anni e voglio viverli più intensamente possibile
A #Sanremo per dare un po' di speranza agli altri pazienti"
#Allevi ospite del #Festival
The ‘Big Five’ carbapenemases:
1️⃣VIM
2️⃣IMP
3️⃣NDM
4️⃣KPC
5️⃣OXA-48
🌟Timeline representing the introduction of carbapenems & the appearance of carbapenemases worldwide. 🌟 #IDXposts
Trapianti e donazioni di organi: è boom. Ma 3 italiani su 10 dicono ancora di no (a salvare altre vite) https://t.co/yVFmYdoa5K
Roma- STATI GENERALI DELLA RETE TRAPIANTOLOGICA ITALIANA, 24-25-26 Gennaio 2024
Esperti al lavoro
@Siaarti_online@agata_team