That’s a wrap on #ASCO2026 Great time presenting late infeftious complications of CAR-T for LBCL patients and catching up with old friends from residency @utswcancer
Check out our most recent publication in @BloodCancerJnl evaluating the prognostic impact of early NGS-based MRD dynamics and cytomolecular risk in newly diagnosed B-cell ALL.
https://t.co/uR43j02ClQ
@NicholasShortMD@DrHKantarjian#Leusm#ALLsm
We report incidence of NPM1-wildtype relapses in pts treated with VEN-based frontline tx in AML.
🔴Overall, absolute # of relapses in NPM1 AML after VEN is ⬇️
🔴the fraction of NPM1-wildtype relapses ⬆️ with the⬆️ intensity of chemo backbone added to VEN.
🔴 NPM1 wildtype relapses occur later and often had MR mutations. And ALL (8/8) had a different flow immunophenotype compared to original AML.
🔴We proposed that these were ‘new’ AMLs, that arose from common preleukemic (CH) precursor, but that the original NPM1-mutated AML was ‘cured’.
https://t.co/MTYuZEW15S
@AjHematology