Mark Nelson

Organic medicinal Tetracycline chemist inventor Nuzyra a FDA drug plus other Tcs- collecting molecules and data all over the world - 2019 ACS Hero of Chemistry.

[Mark Nelson @NelsonMLchemist]

@NaOHBartfield If it’s like the Science I run into it’s probably both- Chlorine? Class? Anyone?

[Mark Nelson @NelsonMLchemist]

@NaOHBartfield A good spectroscopist could tell us what elements and perhaps molecules are involved- class? Anyone?

[Mark Nelson @NelsonMLchemist]

@drugmonkeyblog If you create a drug in a University setting, they take 60% of the royalty stream don’t forget regardless if NIH funded. Can you say Administrative Bloat?

[Mark Nelson @NelsonMLchemist]

@MiraCB007 @MitoPsychoBio Un pasteurized milk or follow the procedure in us patent 8431174 and pull the globs out of whey using diafiltration or chitosan- or just drink whey

[Mark Nelson @NelsonMLchemist]

@brunogomezgil @baym Did they not find resistant E. coli in 250k year old ice cores? I referenced this paper- be back - I was a resistance fighter last wave- we just made new antibiotics

[Mark Nelson @NelsonMLchemist]

@That_Chemist Is compound 10 reactive with nucleophiles? Nice!

[Mark Nelson @NelsonMLchemist]

@drtimothyli Nuzyra as the best Tetracycline for Gram - should have been in the panel. And it’s orally active not like Tygacil.

[Mark Nelson @NelsonMLchemist]

@MitoPsychoBio During OxPhos calcium goes haywire. The tetracyclines induce mitohormesis AND stop calcium induced dysfunction. This family regulates and controls inflammation while no other family compares.

[Mark Nelson @NelsonMLchemist]

@chemiolis It's used all the time in inorganic chem and Li battery research.

[Mark Nelson @NelsonMLchemist]

@sweatystartup Plus the controllers they hold leach plastic endocrine disruptors changing their hormones - biosocial engineering

[Mark Nelson @NelsonMLchemist]

https://t.co/x2CliAN4Iw

We will be presenting at the Society for Neuroscience meeting coming up in DC.

Non- antibiotic Tetracyclines modulate Alzheimer’s by Mitochondrial mechanisms-

Science didn’t see this coming!
Mitochondria are bacteria too!

[Mark Nelson @NelsonMLchemist]

@BStevensonLab Hi Brian- tried to call you. You keep hanging up - probably think I’m a spam call- wanted to talk about my unique collection of Tetracyclines and how to discover better ones- no problem though. Thanks

[Mark Nelson @NelsonMLchemist]

@mkaeberlein Tetracyclines, and not the antibiotic kind- affect C elegan- see our work with the Auwerx lab-regulators of mitos and immunosuppression https://t.co/pr2GDkUZF5.

[Mark Nelson @NelsonMLchemist]

@philipcball Not showing chemical structures is where biology stops and medicinal chemistry begins. Had a discussion- let’s just string heteros together- start a company- we all laughed then didn’t.

[Mark Nelson @NelsonMLchemist]

@BStevensonLab @ItaiYanai Microbiology doesn’t follow week-like rules. Everyday is Monday when running experiments and everyday is Saturday - in my experience

[Mark Nelson @NelsonMLchemist]

@agingdoc1 @statnews Thanks Mom!

[Mark Nelson @NelsonMLchemist]

@BStevensonLab @WilsonLab2 E Coli was used. Great paper. Showed binding of the Tet we invented Nuzyra. Still room for better ones I see!

[Mark Nelson @NelsonMLchemist]

@billthechemist Hi Bill the Chemist- get to booth 445 and meet our team at CPLab Chemicals and Lab Safety- have a periodic table bag for u and others- go Owls! Glad to see you in Chemistry!

[Mark Nelson @NelsonMLchemist]

@drtimothyli Forms quinones on the D ring and condenses too. Good for short term only use.

[American Chemical Society @AmerChemSociety]

The #ACSFall2023 Expo Floor is Open!!! #Chemistry #ChemTwitter